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The Alexander Silberman Institute of Life Sciences & Edmond and Lily Safra Center for Brain Sciences
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Drug-induced ubiquitylation and degradation of ErbB receptor tyrosine kinases: implications for cancer therapy.
The EMBO journal May, 2002 | Pubmed ID: 12006493
The deaf and the dumb: the biology of ErbB-2 and ErbB-3.
Experimental cell research Mar, 2003 | Pubmed ID: 12648465
Polar expression of ErbB-2/HER2 in epithelia. Bimodal regulation by Lin-7.
Developmental cell Sep, 2003 | Pubmed ID: 12967566
The achilles heel of ErbB-2/HER2: regulation by the Hsp90 chaperone machine and potential for pharmacological intervention.
Cell cycle (Georgetown, Tex.) Jan, 2004 | Pubmed ID: 14657666
Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding.
Genes & development Jul, 2004 | Pubmed ID: 15256501
LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation.
The EMBO journal Aug, 2004 | Pubmed ID: 15282549
Hsp90 restrains ErbB-2/HER2 signalling by limiting heterodimer formation.
EMBO reports Dec, 2004 | Pubmed ID: 15568014
Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling.
The Journal of biological chemistry Feb, 2005 | Pubmed ID: 15590694
Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity.
The Journal of biological chemistry Mar, 2005 | Pubmed ID: 15611079
Hsp90 inhibitor 17-AAG reduces ErbB2 levels and inhibits proliferation of the trastuzumab resistant breast tumor cell line JIMT-1.
Immunology letters Apr, 2006 | Pubmed ID: 16384610
Hsp90 recognizes a common surface on client kinases.
The Journal of biological chemistry May, 2006 | Pubmed ID: 16551624
Hsp90 increases LIM kinase activity by promoting its homo-dimerization.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology Jun, 2006 | Pubmed ID: 16641196
Geldanamycins trigger a novel Ron degradative pathway, hampering oncogenic signaling.
The Journal of biological chemistry Aug, 2006 | Pubmed ID: 16740632
EGF-ERBB signalling: towards the systems level.
Nature reviews. Molecular cell biology Jul, 2006 | Pubmed ID: 16829981
A module of negative feedback regulators defines growth factor signaling.
Nature genetics Apr, 2007 | Pubmed ID: 17322878
A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration.
Nature cell biology Aug, 2007 | Pubmed ID: 17643115
Synaptic plasticity: multiple forms, functions, and mechanisms.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Jan, 2008 | Pubmed ID: 17728696
N-methyl-D-aspartate receptor- and metabotropic glutamate receptor-dependent long-term depression are differentially regulated by the ubiquitin-proteasome system.
The European journal of neuroscience Oct, 2009 | Pubmed ID: 19821836
Calcium binding to PICK1 is essential for the intracellular retention of AMPA receptors underlying long-term depression.
The Journal of neuroscience : the official journal of the Society for Neuroscience Dec, 2010 | Pubmed ID: 21147983
Induction of human neuronal cells by defined transcription factors.
Nature Aug, 2011 | Pubmed ID: 21617644
Comprehensive qPCR profiling of gene expression in single neuronal cells.
Nature protocols Jan, 2012 | Pubmed ID: 22193304
Genome-wide association study of multiplex schizophrenia pedigrees.
The American journal of psychiatry Sep, 2012 | Pubmed ID: 22885689
The Hebrew University of Jerusalem
Hagit Turm1,
Diptendu Mukherjee1,
Doron Haritan1,
Maayan Tahor1,
Ami Citri1
1The Alexander Silberman Institute of Life Sciences & Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem
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