Richard D. Schulick

Trends in long-term survival following liver resection for hepatic colorectal metastases.

Periampullary pancreatic somatostatinoma.

Results of pancreaticoduodenectomy for lymphoplasmacytic sclerosing pancreatitis.

Synergistic effect of a granulocyte-macrophage colony-stimulating factor-transduced tumor vaccine and systemic interleukin-2 in the treatment of murine colorectal cancer hepatic metastases.

Aberrant hypermethylation of tumor suppressor genes in pancreatic endocrine neoplasms.

Progression of gene hypermethylation in gallstone disease leading to gallbladder cancer.

Prognostic value of hMLH1 methylation and microsatellite instability in pancreatic endocrine neoplasms.

Analysis of novel tumor markers in pancreatic and biliary carcinomas using tissue microarrays.

Predicting resectability of periampullary cancer with three-dimensional computed tomography.

Expression of neuropilin-1 in high-grade dysplasia, invasive cancer, and metastases of the human gastrointestinal tract.

Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL.

Survival after gastric adenocarcinoma resection: eighteen-year experience at a single institution.

In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses.

Combined PET/CT for detecting recurrent ovarian cancer limited to retroperitoneal lymph nodes.

Endocrine tumors of the pancreas.

Differences in survival for patients with resectable versus unresectable metastases from pancreatic islet cell cancer.

Selective targeting of antitumor immune responses with engineered live-attenuated Listeria monocytogenes.

Resistance of cancers to immunologic cytotoxicity and adoptive immunotherapy via X-linked inhibitor of apoptosis protein expression and coexisting defects in mitochondrial death signaling.

Claudin-4, mitogen-activated protein kinase kinase 4, and stratifin are markers of gastric adenocarcinoma precursor lesions.

Incidence and outcome of biliary strictures after pancreaticoduodenectomy.

Periampullary and pancreatic incidentaloma: a single institution's experience with an increasingly common diagnosis.

A proposed clinical test for monitoring fluoropyrimidine therapy: detection and stability of thymidylate synthase ternary complexes.

Retroperitoneal paraganglioma: single-institution experience and review of the literature.

1423 pancreaticoduodenectomies for pancreatic cancer: A single-institution experience.

Does pancreatic duct stenting decrease the rate of pancreatic fistula following pancreaticoduodenectomy? Results of a prospective randomized trial.

MKK4 status predicts survival after resection of gastric adenocarcinoma.

Preoperative positron emission tomography to evaluate potentially resectable hepatic colorectal metastases.

Cushing's Syndrome attributable to ectopic secretion of corticotropin in a patient with two neuroendocrine tumors.

The Resident's Corner.

The role of cytoreductive surgery for colon cancer metastatic to the ovary.

Effective neoadjuvant therapy prior to metastasectomy: a new paradigm.

Young academic surgeons participating in laboratory and translational research.

Cholangiocarcinoma: thirty-one-year experience with 564 patients at a single institution.

Prognostic relevance of lymph node ratio following pancreaticoduodenectomy for pancreatic cancer.

Biochemical markers predict morbidity and mortality after pancreaticoduodenectomy.

Gallbladder cancer: the role of laparoscopy and radical resection.

Lymphadenopathy, elevated liver function tests and weight loss in a 68-year-old man.

Efficacy of preoperative combined 18-fluorodeoxyglucose positron emission tomography and computed tomography for assessing primary rectal cancer response to neoadjuvant therapy.

Liver-directed surgery for metastatic squamous cell carcinoma to the liver: results of a multi-center analysis.

Trends in survival after surgery for cholangiocarcinoma: a 30-year population-based SEER database analysis.

Incidence of finding residual disease for incidental gallbladder carcinoma: implications for re-resection.

Palliative management of gastric cancer.

Impact of total lymph node count and lymph node ratio on staging and survival after pancreatectomy for pancreatic adenocarcinoma: a large, population-based analysis.

Racial and geographic disparities in the utilization of surgical therapy for hepatocellular carcinoma.

Is resection of periampullary or pancreatic adenocarcinoma with synchronous hepatic metastasis justified?

Live attenuated Listeria monocytogenes effectively treats hepatic colorectal cancer metastases and is strongly enhanced by depletion of regulatory T cells.

Acinar cell carcinoma of the pancreas: an institutional series of resected patients and review of the current literature.

Duodenojejunostomy leaks after pancreaticoduodenectomy.

Primary sclerosing cholangitis: detection of cancer in strictures.

Expanding criteria for resectability of colorectal liver metastases.

Operative mortality after hepatic resection: are literature-based rates broadly applicable?

Evaluating the impact of a single-day multidisciplinary clinic on the management of pancreatic cancer.

Primary sclerosing cholangitis: role of extrahepatic biliary resection.

Choledochal cyst disease in children and adults: a 30-year single-institution experience.

Management of gastrointestinal stromal tumors.

Complications after pancreaticoduodenectomy: intraabdominal abscess.

Analysis of fluorouracil-based adjuvant chemotherapy and radiation after pancreaticoduodenectomy for ductal adenocarcinoma of the pancreas: results of a large, prospectively collected database at the Johns Hopkins Hospital.

Incidence and management of chyle leaks following pancreatic resection: a high volume single-center institutional experience.

Patterns of recurrence following liver resection for colorectal metastases: effect of primary rectal tumor site.

A quantitative proteomic approach for identification of potential biomarkers in hepatocellular carcinoma.

Racial disparity in surgical mortality after major hepatectomy.

Pancreatic resection of isolated metastases from nonpancreatic primary cancers.

Is surgery required for patients with intraductal papillary mucinous neoplasms without mural nodules?

Activated epidermal growth factor receptor as a novel target in pancreatic cancer therapy.

A proposed staging system for intrahepatic cholangiocarcinoma.

Trends in nontherapeutic laparotomy rates in patients undergoing surgical therapy for hepatic colorectal metastases.

Peri-operative mortality and long-term survival after total pancreatectomy for pancreatic adenocarcinoma: a population-based perspective.

Colorectal liver metastases: recurrence and survival following hepatic resection, radiofrequency ablation, and combined resection-radiofrequency ablation.

Determining pattern of recurrence following pancreaticoduodenectomy and adjuvant 5-flurouracil-based chemoradiation therapy: effect of number of metastatic lymph nodes and lymph node ratio.

Liver cell adenoma: a multicenter analysis of risk factors for rupture and malignancy.

Predictors of survival after resection of early hepatocellular carcinoma.

Surgical treatment of resectable and borderline resectable pancreas cancer: expert consensus statement.

Stents, glue, etc.: is anything proven to help prevent pancreatic leaks/fistulae?

The volume-outcomes effect in hepato-pancreato-biliary surgery: hospital versus surgeon contributions and specificity of the relationship.

Surgical management of solid-pseudopapillary neoplasms of the pancreas (Franz or Hamoudi tumors): a large single-institutional series.

Cyclophosphamide resets dendritic cell homeostasis and enhances antitumor immunity through effects that extend beyond regulatory T cell elimination.

Implementing a team-based daily goals sheet in a non-ICU setting.

The Clavien-Dindo classification of surgical complications: five-year experience.

Total pancreatectomy for pancreatic adenocarcinoma: evaluation of morbidity and long-term survival.

Risk factors for pancreatic leak after distal pancreatectomy.

Predictors of survival after resection of retroperitoneal sarcoma: a population-based analysis and critical appraisal of the AJCC staging system.

Adjuvant chemoradiotherapy after pancreatic resection for invasive carcinoma associated with intraductal papillary mucinous neoplasm of the pancreas.

Rates and patterns of recurrence following curative intent surgery for colorectal liver metastasis: an international multi-institutional analysis of 1669 patients.

Integrin alpha2 mediates selective metastasis to the liver.

Comparative performances of staging systems for early hepatocellular carcinoma.

Repeat curative intent liver surgery is safe and effective for recurrent colorectal liver metastasis: results from an international multi-institutional analysis.

Clinicopathologic analysis of ampullary neoplasms in 450 patients: implications for surgical strategy and long-term prognosis.

Variations in referral patterns to high-volume centers for pancreatic cancer.

Adjuvant chemoradiation for pancreatic adenocarcinoma: the Johns Hopkins Hospital-Mayo Clinic collaborative study.

Histopathologic basis for the favorable survival after resection of intraductal papillary mucinous neoplasm-associated invasive adenocarcinoma of the pancreas.

Sclerosing mesenteritis involving the pancreas: a mimicker of pancreatic cancer.

Conditional survival after surgical resection of colorectal liver metastasis: an international multi-institutional analysis of 949 patients.

Immuno- and gene-therapeutic strategies targeted against cancer (mainly focusing on pancreatic cancer).

Impact of obesity on perioperative outcomes and survival following pancreaticoduodenectomy for pancreatic cancer: a large single-institution study.

Hepatic resection for colorectal metastases: the impact of surgical margin status on outcome.

Liver-directed therapy for hepatic metastases in patients undergoing pancreaticoduodenectomy: a dual-center analysis.

Preoperative endoscopic tattooing of pancreatic body and tail lesions decreases operative time for laparoscopic distal pancreatectomy.

Impact of the Comprehensive Unit-based Safety Program (CUSP) on safety culture in a surgical inpatient unit.

Surgical management of hepatic neuroendocrine tumor metastasis: results from an international multi-institutional analysis.

Two-stage strategy for patients with extensive bilateral colorectal liver metastases.

Adjuvant chemoradiation therapy after pancreaticoduodenectomy in elderly patients with pancreatic adenocarcinoma.

Pancreatic duct stenosis secondary to small endocrine neoplasms: a manifestation of serotonin production?

Safety and efficacy of curative intent surgery for peri-ampullary liver metastasis.

National trends in the management and survival of surgically managed gallbladder adenocarcinoma over 15 years: a population-based analysis.

Disappearing colorectal liver metastases after chemotherapy: should we be concerned?

EUS-guided tattooing before laparoscopic distal pancreatic resection (with video).

Therapeutic efficacy of combined intraoperative ablation and resection for colorectal liver metastases: an international, multi-institutional analysis.

Liver resection for colorectal metastases in presence of extrahepatic disease: results from an international multi-institutional analysis.

Differentiating intraductal papillary mucinous neoplasms from other pancreatic cystic lesions.

Transitoriness in cancer patients: a cross-sectional survey of lung and gastrointestinal cancer patients.

Understanding surgical decision making in early hepatocellular carcinoma.

Undertreatment of patients with early-stage hepatocellular carcinoma: Comment on "Racial/ethnic disparities in access to care and survival for patients with early-stage hepatocellular carcinoma".

DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors.

Re-evaluating the impact of tumor size on survival following pancreaticoduodenectomy for pancreatic adenocarcinoma.

Cystic precursors to invasive pancreatic cancer.

The role of liver-directed surgery in patients with hepatic metastasis from a gynecologic primary carcinoma.

Tumor size and location correlate with behavior of pancreatic serous cystic neoplasms.

New staging system and a registry for perihilar cholangiocarcinoma.

Presence of pancreatic intraepithelial neoplasia in the pancreatic transection margin does not influence outcome in patients with R0 resected pancreatic cancer.

Loss of E-cadherin expression and outcome among patients with resectable pancreatic adenocarcinomas.

Hyaline globules in neuroendocrine and solid-pseudopapillary neoplasms of the pancreas: a clue to the diagnosis.

Solitary fibrous tumour of the rectosigmoid wall: report of a case and review of the literature.

Surgery versus intra-arterial therapy for neuroendocrine liver metastasis: a multicenter international analysis.

Sarcopenia negatively impacts short-term outcomes in patients undergoing hepatic resection for colorectal liver metastasis.

Refining the definition of perioperative mortality following hepatectomy using death within 90 days as the standard criterion.

Hilar cholangiocarcinoma: tumor depth as a predictor of outcome.

Pulmonary resection for isolated pancreatic adenocarcinoma metastasis: an analysis of outcomes and survival.

Intrahepatic cholangiocarcinoma: an international multi-institutional analysis of prognostic factors and lymph node assessment.

Colorectal liver metastasis in the setting of lymph node metastasis: defining the benefit of surgical resection.

Elevated microRNA miR-21 levels in pancreatic cyst fluid are predictive of mucinous precursor lesions of ductal adenocarcinoma.

Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development.

Small serotonin-producing neuroendocrine tumor of the pancreas associated with pancreatic duct obstruction.

Diagnosis and management of cystic lesions of the pancreas.

Palliative surgical management of patients with unresectable pancreatic adenocarcinoma: trends and lessons learned from a large, single institution experience.

Use of pancreatic duct stents after pancreaticoduodenectomy.

Conditional survival in patients with pancreatic ductal adenocarcinoma resected with curative intent.

Loss of expression of the SWI/SNF chromatin remodeling subunit BRG1/SMARCA4 is frequently observed in intraductal papillary mucinous neoplasms of the pancreas.

Evaluation of adjuvant chemoradiation therapy for ampullary adenocarcinoma: the Johns Hopkins Hospital-Mayo Clinic collaborative study.

National trends in surgical procedures for hepatocellular carcinoma: 1998-2008.

Management of patients with pancreatic adenocarcinoma: national trends in patient selection, operative management, and use of adjuvant therapy.

Vascular invasion in infiltrating ductal adenocarcinoma of the pancreas can mimic pancreatic intraepithelial neoplasia: a histopathologic study of 209 cases.

Predicting the risk of perioperative mortality in patients undergoing pancreaticoduodenectomy: a novel scoring system.

Pancreatic surgery for the radiologist, 2011: an illustrated review of classic and newer surgical techniques for pancreatic tumor resection.

Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways.

Clinicopathological characteristics and molecular analyses of multifocal intraductal papillary mucinous neoplasms of the pancreas.

Duodenal adenocarcinoma: clinicopathologic analysis and implications for treatment.

Serotonin expression in pancreatic neuroendocrine tumors correlates with a trabecular histologic pattern and large duct involvement.

Small cell and large cell neuroendocrine carcinomas of the pancreas are genetically similar and distinct from well-differentiated pancreatic neuroendocrine tumors.

Patient readmission and mortality after colorectal surgery for colon cancer: impact of length of stay relative to other clinical factors.

Early mortality risk score: identification of poor outcomes following upfront surgery for resectable pancreatic cancer.

The impact of portal vein resection on outcomes for hilar cholangiocarcinoma: a multi-institutional analysis of 305 cases.

Laparoscopic distal pancreatectomy is associated with significantly less overall morbidity compared to the open technique: a systematic review and meta-analysis.

Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors.

Impact of sarcopenia on outcomes following resection of pancreatic adenocarcinoma.

Presence of pancreatic intraepithelial neoplasia in the pancreatic transection margin does not influence outcome in patients with R0 resected pancreatic cancer.

miRNA biomarkers in cyst fluid augment the diagnosis and management of pancreatic cysts.

Sequential intra-arterial therapy and portal vein embolization is feasible and safe in patients with advanced hepatic malignancies.

Glycolipid antigens for treating hepatic colorectal cancer metastases and their effect on the therapeutic efficacy of live attenuated Listeria monocytogenes.

Improvements in quality of life after surgery for benign hepatic tumors: Results from a dual center analysis.

Effect of metabolic syndrome on perioperative outcomes after liver surgery: A National Surgical Quality Improvement Program (NSQIP) analysis.

Treating patients with colon cancer liver metastasis: a nationwide analysis of therapeutic decision making.

Comparison of conventional and 3-dimensional computed tomography against histopathologic examination in determining pancreatic adenocarcinoma tumor size: implications for radiation therapy planning.

Influence of nonclinical factors on choice of therapy for early hepatocellular carcinoma.

GNAS codon 201 mutations are uncommon in intraductal papillary neoplasms of the bile duct.

Cystic pancreatic neuroendocrine tumors: a clinicopathologic study.

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.

Young patients undergoing resection of pancreatic cancer fare better than their older counterparts.

Prognosis of minimally invasive carcinoma arising in mucinous cystic neoplasms of the pancreas.

Is it necessary to follow patients after resection of a benign pancreatic intraductal papillary mucinous neoplasm?

A single institution's 26-year experience with nonfunctional pancreatic neuroendocrine tumors: a validation of current staging systems and a new prognostic nomogram.

Phase 2 study of erlotinib combined with adjuvant chemoradiation and chemotherapy in patients with resectable pancreatic cancer.

Pancreaticoduodenectomy using perioperative zymogen protein C to help prevent blood clotting: a trilogy on increased patient safety.

Serendipity in the diagnosis of pheochromocytoma.

Correlation of Smad4 status with outcomes in patients receiving erlotinib combined with adjuvant chemoradiation and chemotherapy after resection for pancreatic adenocarcinoma.

Acinar cell cystadenoma of the pancreas: a benign neoplasm or non-neoplastic ballooning of acinar and ductal epithelium?

Grading of well-differentiated pancreatic neuroendocrine tumors is improved by the inclusion of both Ki67 proliferative index and mitotic rate.

Sometimes consensus and expert opinion is the best we can do.

Bridging the gap from T to K: integrated surgical research fellowship for the next generation of surgical scientists.

A Safety and Feasibility Study of an Allogeneic Colon Cancer Cell Vaccine Administered with a Granulocyte-Macrophage Colony Stimulating Factor-Producing Bystander Cell Line in Patients with Metastatic Colorectal Cancer.

Racial disparities in breast cancer: more bad news.

Clearing Common Bile Duct Stones: One Size Does Not Fit All.