Anthony Atala

Re: Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.

Re: The cancer/testis antigen prostate-associated gene 4 (PAGE4) is a highly intrinsically disordered protein.

Re: Developmental control of apoptosis by the immunophilin aryl hydrocarbon receptor-interacting protein (AIP) involves mitochondrial import of the survivin protein.

Re: reconstitution of experimental neurogenic bladder dysfunction using skeletal muscle-derived multipotent stem cells.

Re: Innervation of Reconstructed Bladder Above the Level of Spinal Cord Injury for Inducing Micturition by Contractions of the Abdomen-to-Bladder Reflex Arc.

Regenerative medicine strategies for treating neurogenic bladder.

Re: therapeutic potential of human mesenchymal stem cells producing IL-12 in a mouse xenograft model of renal cell carcinoma.

Re: early life inorganic lead exposure induces testicular teratoma and renal and urinary bladder preneoplasia in adult metallothionein-knockout mice but not in wild type mice.

Re: a novel imaging approach for early detection of prostate cancer based on endogenous zinc sensing.

Re: nonsteroidal selective androgen receptor modulators enhance female sexual motivation.

Re: eIF4E Phosphorylation Promotes Tumorigenesis and is Associated With Prostate Cancer Progression.

Re: fkbp52 regulates androgen receptor transactivation activity and male urethra morphogenesis.

Tissue engineering: current strategies and future directions.

Re: TRPA1 receptor modulation attenuates bladder overactivity induced by spinal cord injury.

Re: Testosterone replacement effectively inhibits the development of experimental autoimmune orchitis in rats: evidence for a direct role of testosterone on regulatory T cell expansion.

Tissue engineering of the penis.

Muscle precursor cells for the restoration of irreversibly damaged sphincter function.

Re: licensing of gametogenesis, dependent on RNA binding protein DAZL, as a gateway to sexual differentiation of fetal germ cells.

Re: β-catenin is essential for Müllerian duct regression during male sexual differentiation.

Regenerative medicine strategies.

Cell and organ bioengineering technology as applied to gastrointestinal diseases.

Human embryonic stem cells: early hints on safety and efficacy.

In vitro reconstitution of human kidney structures for renal cell therapy.

A rat decellularized small bowel scaffold that preserves villus-crypt architecture for intestinal regeneration.

Re: epigenetic regulation of phosphatidylinositol 3,4,5-triphosphate-dependent Rac exchanger 1 gene expression in prostate cancer cells.

Re: targeting the regulation of androgen receptor signaling by the heat shock protein 90 cochaperone FKBP52 in prostate cancer cells.

Re: IGFBP-3 is a metastasis suppression gene in prostate cancer.

Regenerative medicine as applied to general surgery.

Amniotic fluid-derived stem cells in regenerative medicine research.

An emerging cell-based strategy in orthopaedics: endothelial progenitor cells.

Editorial: effective bio-economic approaches for stem cell therapy and regenerative medicine.

Re: An inducible model of abacterial prostatitis induces antigen specific inflammatory and proliferative changes in the murine prostate.

Re: Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche.

Engineering functional bladder tissues.

Tissue specific synthetic ECM hydrogels for 3-D in vitro maintenance of hepatocyte function.

Re: DMRT1 prevents female reprogramming in the postnatal mammalian testis.

Re: prevention of maternal aging-associated oocyte aneuploidy and meiotic spindle defects in mice by dietary and genetic strategies.

Re: the E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis.

Bilayered constructs aimed at osteochondral strategies: the influence of medium supplements in the osteogenic and chondrogenic differentiation of amniotic fluid-derived stem cells.

Functional recovery of completely denervated muscle: implications for innervation of tissue-engineered muscle.

Re: Generation of a mouse model of Von Hippel-Lindau kidney disease leading to renal cancers by expression of a constitutively active mutant of HIF1α.

Re: Cancer cells promote survival through depletion of the von Hippel-Lindau tumor suppressor by protein crosslinking.

Re: Targeting PIM kinase enhances the activity of sunitinib in renal cell carcinoma.

The effect of differentiation stage of amniotic fluid stem cells on bone regeneration.

Re: SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia.

Re: PC3 is a cell line characteristic of prostatic small cell carcinoma.

Re: Ligand-dependent corepressor acts as a novel androgen receptor corepressor, inhibits prostate cancer growth, and is functionally inactivated by the Src protein kinase.

Re: Inhibition of neurotensin receptor 1 selectively sensitizes prostate cancer to ionizing radiation.

Production and implantation of renal extracellular matrix scaffolds from porcine kidneys as a platform for renal bioengineering investigations.

Tissue engineering of reproductive tissues and organs.

Valproic acid confers functional pluripotency to human amniotic fluid stem cells in a transgene-free approach.

The effect of controlled release of PDGF-BB from heparin-conjugated electrospun PCL/gelatin scaffolds on cellular bioactivity and infiltration.

Re: Acquired platinum resistance enhances tumour angiogenesis through angiotensin II type 1 receptor in bladder cancer.

Re: Sexual selection by female immunity against paternal antigens can fix loss of function alleles.

Safeguarding pluripotent stem cells for cell therapy with a non-viral, non-integrating episomal suicide construct.

Decellularization methods of porcine kidneys for whole organ engineering using a high-throughput system.

Cell-seeded tubularized scaffolds for reconstruction of long urethral defects: a preclinical study.

Re: Uric acid stones in the urinary bladder of aryl hydrocarbon receptor (AhR) knockout mice.

Re: CECR2 is involved in spermatogenesis and forms a complex with SNF2H in the testis.

Re: High-fat diet activates pro-inflammatory response in the prostate through association of Stat-3 and NF-κB.

Amniotic fluid-derived stem cells as a cell source for bone tissue engineering.

Human amniotic fluid stem cell injection therapy for urethral sphincter regeneration in an animal model.

Bioengineered vascular access maintains structural integrity in response to arteriovenous flow and repeated needle puncture.

Evaluation of hydrogels for bio-printing applications.

Re: Collective and single cell behavior in epithelial contact inhibition.

Re: Nanoencapsulated anti-CK2 small molecule drug or siRNA specifically targets malignant cancer but not benign cells.

Re: Three-dimensional cancer-bone metastasis model using ex-vivo co-cultures of live calvarial bones and cancer cells.

Organ engineering--combining stem cells, biomaterials, and bioreactors to produce bioengineered organs for transplantation.

End-to-side neurorrhaphy using an electrospun PCL/collagen nerve conduit for complex peripheral motor nerve regeneration.

Controlled regulation of erythropoietin by primary cultured renal cells for renal failure induced anemia.

Human amnion epithelial cells induced to express functional cystic fibrosis transmembrane conductance regulator.

Ischemia/reperfusion-induced renal failure in rats as a model for evaluating cell therapies.

Human mid-trimester amniotic fluid stem cells cultured under embryonic stem cell conditions with valproic acid acquire pluripotent characteristics.

Re: Prostate cancer targeting motifs: expression of αν β3, neurotensin receptor 1, prostate specific membrane antigen, and prostate stem cell antigen in human prostate cancer cell lines and xenografts.

Re: Inactivation of androgen-induced regulator ARD1 inhibits androgen receptor acetylation and prostate tumorigenesis.

Re: GPRC6A regulates prostate cancer progression.

Complex heterogeneous tissue constructs containing multiple cell types prepared by inkjet printing technology.

Urothelial cell culture: stratified urothelial sheet and three-dimensional growth of urothelial structure.

MYC gene delivery to adult mouse utricles stimulates proliferation of postmitotic supporting cells in vitro.

Substrate elasticity controls cell proliferation, surface marker expression and motile phenotype in amniotic fluid-derived stem cells.

Skeletal myogenic differentiation of urine-derived stem cells and angiogenesis using microbeads loaded with growth factors.

Re: A unifying model for mTORC1-mediated regulation of mRNA translation.

Re: VHL-Regulated miR-204 suppresses tumor growth through inhibition of LC3B-mediated autophagy in renal clear cell carcinoma.

Re: Orthotopic grafting of cryopreserved prepubertal testicular tissue: in search of a simple yet effective cryopreservation protocol.

Pdx1 and controlled culture conditions induced differentiation of human amniotic fluid-derived stem cells to insulin-producing clusters.

Engineering complex tissues.

Hybrid printing of mechanically and biologically improved constructs for cartilage tissue engineering applications.

Penile urethra replacement with autologous cell-seeded tubularized collagen matrices.

Advent and maturation of regenerative medicine.

A new era in stem cells translational medicine.

Bioprinted amniotic fluid-derived stem cells accelerate healing of large skin wounds.

Cell therapy with human renal cell cultures containing erythropoietin-positive cells improves chronic kidney injury.

Re: MicroRNA-449a acts as a tumor suppressor in human bladder cancer through the regulation of pocket proteins.

Re: An epirubicin-conjugated nanocarrier with MRI function to overcome lethal multidrug-resistant bladder cancer.

Robotic assisted ureteral reimplantation: current status.

Engineered multilayer ovarian tissue that secretes sex steroids and peptide hormones in response to gonadotropins.

Segmental ulcerated perineal hemangioma of infancy: a complex case of PELVIS syndrome successfully treated using a multidisciplinary approach.

Genetic modification of primate amniotic fluid-derived stem cells produces pancreatic progenitor cells in vitro.

Re: overexpression of androgen receptor enhances the binding of the receptor to the chromatin in prostate cancer.

Re: simultaneous inhibition of two regulatory T-cell subsets enhanced interleukin-15 efficacy in a prostate tumor model.

Re: akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, e3 ligase activity, and DNA damage repair activity in mouse prostate cancer.

Re: Nkx3.1 and myc crossregulate shared target genes in mouse and human prostate tumorigenesis.

Stem cells translational medicine: the journal of tomorrow is a reality today.

Amniotic fluid and placental membranes: unexpected sources of highly multipotent cells.

Self-renewal and differentiation capacity of urine-derived stem cells after urine preservation for 24 hours.

Controllable dual protein delivery through electrospun fibrous scaffolds with different hydrophilicities.

In vitro osteogenic differentiation of human amniotic fluid-derived stem cells on a poly(lactide-co-glycolide) (PLGA)-bladder submucosa matrix (BSM) composite scaffold for bone tissue engineering.

Scaffold technologies for controlling cell behavior in tissue engineering.

The effect of in vitro formation of acetylcholine receptor (AChR) clusters in engineered muscle fibers on subsequent innervation of constructs in vivo.

Re: Ca(2+)/calmodulin-dependent protein kinase II is associated with pelvic pain of neurogenic cystitis.

Re: tumor radiation response enhancement by acoustical stimulation of the vasculature.

Re: synapse-directed delivery of immunomodulators using T-cell-conjugated nanoparticles.

Functional recovery of denervated muscle by neurotization using nerve guidance channels.

Stem cell advances and challenges.

Amniotic fluid stem cells improve survival and enhance repair of damaged intestine in necrotising enterocolitis via a COX-2 dependent mechanism.

Re: effectiveness of a combination therapy using calcineurin inhibitor and mTOR inhibitor in preventing allograft rejection and post-transplantation renal cancer progression.

Re: cancer stem-like cells contribute to Cisplatin resistance and progression in bladder cancer.

Re: potential role of hsp90 inhibitors in overcoming Cisplatin resistance of bladder cancer-initiating cells.

Porcine pancreas extracellular matrix as a platform for endocrine pancreas bioengineering.

Re: JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate.

Re: TP53INP1 as new therapeutic target in castration-resistant prostate cancer.

Re: a gene signature identified using a mouse model of androgen receptor-dependent prostate cancer predicts biochemical relapse in human disease.

Re: Protease nexin 1 inhibits hedgehog signaling in prostate adenocarcinoma.

Re: Both osteopontin-c and osteopontin-b splicing isoforms exert pro-tumorigenic roles in prostate cancer cells.

Re: Inhibition of Ca2+ -activated Cl- channel ANO1/TMEM16A expression suppresses tumor growth and invasiveness in human prostate carcinoma.

Multipotential differentiation of human urine-derived stem cells: potential for therapeutic applications in urology.

Preservation of micro-architecture and angiogenic potential in a pulmonary acellular matrix obtained using intermittent intra-tracheal flow of detergent enzymatic treatment.

Re: a new experimental rat model of erectile dysfunction and lower urinary tract symptoms associated with benign prostatic hyperplasia: the testosterone-supplemented spontaneously hypertensive rat.

Re: glucocorticoid mediates water avoidance stress-sensitized colon-bladder cross-talk via RSK2/PSD-95/NR2B in rats.

Re: NMR-based metabolomics study of canine bladder cancer.

Cell therapy for cystic fibrosis.

Bladder acellular matrix and its application in bladder augmentation.

Will regenerative medicine replace transplantation?

Re: PIK3CA mutation spectrum in urothelial carcinoma reflects cell context-dependent signaling and phenotypic outputs.

Re: p21-activated kinase 6 (PAK6) inhibits prostate cancer growth via phosphorylation of androgen receptor and tumorigenic E3 ligase murine double minute-2 (Mdm2).

Re: Cox-2 inhibition enhances the activity of sunitinib in human renal cell carcinoma xenografts.

The effect of urine-derived stem cells expressing VEGF loaded in collagen hydrogels on myogenesis and innervation following after subcutaneous implantation in nude mice.

Diaphragmatic muscle reconstruction with an aligned electrospun poly(ε-caprolactone)/collagen hybrid scaffold.

Isolation of c-Kit+ Human Amniotic Fluid Stem Cells from Second Trimester.

Correction of diabetic erectile dysfunction with adipose derived stem cells modified with the vascular endothelial growth factor gene in a rodent diabetic model.

Re: Shrinkage of experimental benign prostatic hyperplasia and reduction of prostatic cell volume by a gastrin-releasing peptide antagonist.

Re: Down-regulation of CatSper1 channel in epididymal spermatozoa contributes to the pathogenesis of asthenozoospermia, whereas up-regulation of the Channel by Sheng-Jing-San treatment improves the sperm motility of asthenozoospermia in rats.

Re: Downregulation of Ral GTPase-activating protein promotes tumor invasion and metastasis of bladder cancer.

Urothelial cell culture.

Re: PRC1 coordinates timing of sexual differentiation of female primordial germ cells.

Re: Aire-dependent thymic development of tumor-associated regulatory T cells.

Re: Loss of β1-integrin from urothelium results in overactive bladder and incontinence in mice: a mechanosensory rather than structural phenotype.

Re: Extracellular UDP enhances P2X-mediated bladder smooth muscle contractility via P2Y6 activation of the phospholipase C/Inositol trisphosphate pathway.

Re: Long non-coding RNA H19 increases bladder cancer metastasis by associating with EZH2 and inhibiting E-cadherin expression.

In situ tissue regeneration through host stem cell recruitment.

Small molecules and small molecule drugs in regenerative medicine.

Re: CSF1R signaling blockade stanches tumor-infiltrating myeloid cells and improves the efficacy of radiotherapy in prostate cancer.

Organ preservation, organ and cell transplantation, tissue engineering, and regenerative medicine: the terms may change, but the goals remain the same.

Understanding the role of growth factors in modulating stem cell tenogenesis.

SIU/ICUD Consultation on Urethral Strictures: The management of anterior urethral stricture disease using substitution urethroplasty.

Re: missense mutations in SLC26A8, encoding a sperm-specific activator of CFTR, are associated with human asthenozoospermia.

Re: decreased androgen receptor expression may contribute to spermatogenesis failure in rats exposed to low concentration of bisphenol A.

Re: activation of HIF2α in kidney proximal tubule cells causes abnormal glycogen deposition but not tumorigenesis.

Stem cells translational medicine: exciting progress, growing partnerships, and new vehicles for information dissemination.

Can computed tomography--assisted virtual endoscopy be an innovative tool for detecting urethral tissue pathologies?

Re: antitumoral effects of vasoactive intestinal peptide in human renal cell carcinoma xenografts in athymic nude mice.

Re: enhanced therapeutic effect of cisplatin on the prostate cancer in tumor-bearing mice by transfecting the attenuated salmonella carrying a plasmid co-expressing p53 gene and MDM2 siRNA.

Re: telomere length influences cancer cell differentiation in vivo.

Downregulation of metabolic activity increases cell survival under hypoxic conditions: potential applications for tissue engineering.

Regenerative medicine: the hurdles and hopes.

Tissue engineering in urethral reconstruction.

Myogenic-induced mesenchymal stem cells are capable of modulating the immune response by regulatory T cells.

Regenerative bladder augmentation using autologous tissue-when will we get there?

Auricular reconstruction using tissue-engineered alloplastic implants for improved clinical outcomes.

Re: Gene signatures distinguish stage-specific prostate cancer stem cells isolated from transgenic adenocarcinoma of the mouse prostate lesions and predict the malignancy of human tumors.

Re: Differential stage-dependent regulation of prostatic epithelial morphogenesis by Hedgehog signaling.

Re: miR-182 and miR-203 induce mesenchymal to epithelial transition and self-sufficiency of growth signals via repressing SNAI2 in prostate cells.

Tissue-engineered autologous vaginal organs in patients: a pilot cohort study.

Re: lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs.

Re: enhanced susceptibility to urinary tract infection in the spinal cord-injured host with neurogenic bladder.

Re: basigin null mutant male mice are sterile and exhibit impaired interactions between germ cells and Sertoli cells.

Renal bioengineering with scaffolds generated from human kidneys.

Skeletal myogenic differentiation of human urine-derived cells as a potential source for skeletal muscle regeneration.

In situ regeneration of skeletal muscle tissue through host cell recruitment.

Regenerative medicine in urology.

Re: The long noncoding RNA SChLAP1 promotes aggressive prostate cancer and antagonizes the SWI/SNF complex.

Re: Dietary sources of N-nitroso compounds and bladder cancer risk: findings from the Los Angeles Bladder Cancer Study.

Re: Carvedilol efficiently protects kidneys without affecting the antitumor efficacy of cisplatin in mice.

Bioprinting technology and its applications.

3D bioprinting of tissues and organs.

Airway tissue engineering: an update.

Testicular tissue cryopreservation and spermatogonial stem cell transplantation to restore fertility: from bench to bedside.

Syngeneic myoblast transplantation improves muscle function in a murine model of X-linked myotubular myopathy.

Re: TALEN-engineered AR gene rearrangements reveal endocrine uncoupling of androgen receptor in prostate cancer.

Re: bispecific small molecule-antibody conjugate targeting prostate cancer.

Re: leptin signaling in GABA neurons, but not glutamate neurons, is required for reproductive function.

Kidney regeneration: Where we are and future perspectives.

Quantitative assessment of barriers to the clinical development and adoption of cellular therapies: A pilot study.

Applicability and safety of in vitro skin expansion using a skin bioreactor: a clinical trial.

Editorial: bringing regenerative medicine therapies to the 21st century.

Bioengineered transplantable porcine livers with re-endothelialized vasculature.

Regenerative medicine for the treatment of reproductive system disorders: Current and potential options.

Human stem cell-derived retinal cells for macular diseases.

Multilayer scaffolds in orthopaedic tissue engineering.

Biomaterials for Integration with 3-D Bioprinting.