Alexander F. Schier

Department of Molecular and Cellular Biology, Harvard University

Research Area

Developmental Biology

Biography

Alexander F. Schier has not added Biography.
If you are Alexander F. Schier and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2015

Other Publications

Article	Year
Stat3 Controls Cell Movements during Zebrafish Gastrulation. Developmental cell\| PubMed ID: 11879641	2002
A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects. Human genetics\| PubMed ID: 12073012	2002
A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening. Journal of the American Chemical Society\| PubMed ID: 12296721	2002
Mesoderm induction and patterning. Results and problems in cell differentiation\| PubMed ID: 12353475	2002
Production of maternal-zygotic mutant zebrafish by germ-line replacement. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12397179	2002
Lefty proteins are long-range inhibitors of squint-mediated nodal signaling. Current biology : CB\| PubMed ID: 12498687	2002
EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1. Genes & development\| PubMed ID: 12514096	2003
Chemokine signaling: rules of attraction. Current biology : CB\| PubMed ID: 12620211	2003
Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. Development (Cambridge, England)\| PubMed ID: 12620981	2003
The role of the zebrafish nodal-related genes squint and cyclops in patterning of mesendoderm. Development (Cambridge, England)\| PubMed ID: 12642489	2003
Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction. Development (Cambridge, England)\| PubMed ID: 14522874	2003
Nodal signaling in vertebrate development. Annual review of cell and developmental biology\| PubMed ID: 14570583	2003
Developmental biology: tail of decay. Nature\| PubMed ID: 14749811	2004
Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors. PLoS biology\| PubMed ID: 14966532	2004
Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling. Developmental biology\| PubMed ID: 15617692	2005
Nodal stability determines signaling range. Current biology : CB\| PubMed ID: 15649361	2005
MicroRNAs regulate brain morphogenesis in zebrafish. Science (New York, N.Y.)\| PubMed ID: 15774722	2005
Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis. Development (Cambridge, England)\| PubMed ID: 15790966	2005
Repulsive interactions shape the morphologies and functional arrangement of zebrafish peripheral sensory arbors. Current biology : CB\| PubMed ID: 15886097	2005
Assembly of trigeminal sensory ganglia by chemokine signaling. Neuron\| PubMed ID: 16129396	2005
Molecular genetics of axis formation in zebrafish. Annual review of genetics\| PubMed ID: 16285872	2005
Axis formation: squint comes into focus. Current biology : CB\| PubMed ID: 16360671	2005
Planar cell polarity signalling couples cell division and morphogenesis during neurulation. Nature\| PubMed ID: 16407953	2006
Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science (New York, N.Y.)\| PubMed ID: 16484454	2006
Polycystin-2 immunolocalization and function in zebrafish. Journal of the American Society of Nephrology : JASN\| PubMed ID: 16943304	2006
Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430. Current biology : CB\| PubMed ID: 17084698	2006
Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 17182791	2006
Nodal signaling activates differentiation genes during zebrafish gastrulation. Developmental biology\| PubMed ID: 17306247	2007
The maternal-zygotic transition: death and birth of RNAs. Science (New York, N.Y.)\| PubMed ID: 17446392	2007
Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430. Science (New York, N.Y.)\| PubMed ID: 17761850	2007
Maternal nodal and zebrafish embryogenesis. Nature\| PubMed ID: 17994032	2007
Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron\| PubMed ID: 18184563	2008
Clearing the path for germ cells. Cell\| PubMed ID: 18267065	2008
Targeted mutagenesis in zebrafish. Nature biotechnology\| PubMed ID: 18536686	2008
Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons. Current biology : CB\| PubMed ID: 18682213	2008
In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis. Development (Cambridge, England)\| PubMed ID: 18755773	2008
Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18829968	2008
Nodal signaling promotes the speed and directional movement of cardiomyocytes in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 18985714	2008
Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia. Development (Cambridge, England)\| PubMed ID: 19700616	2009
Developmental biology: Rise of the source-sink model. Nature\| PubMed ID: 19779439	2009
Nodal morphogens. Cold Spring Harbor perspectives in biology\| PubMed ID: 20066122	2009
Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation. Science (New York, N.Y.)\| PubMed ID: 20075256	2010
no tail integrates two modes of mesoderm induction. Development (Cambridge, England)\| PubMed ID: 20215349	2010
Monitoring neural activity with bioluminescence during natural behavior. Nature neuroscience\| PubMed ID: 20305645	2010
Chromatin signature of embryonic pluripotency is established during genome activation. Nature\| PubMed ID: 20336069	2010
Monitoring sleep and arousal in zebrafish. Methods in cell biology\| PubMed ID: 21111222	2010
Multicolor Brainbow imaging in zebrafish. Cold Spring Harbor protocols\| PubMed ID: 21205846	2011
Non-coding RNAs as regulators of embryogenesis. Nature reviews. Genetics\| PubMed ID: 21245830	2011
Behavioral screening for neuroactive drugs in zebrafish. Developmental neurobiology\| PubMed ID: 21567979	2011
Extracellular movement of signaling molecules. Developmental cell\| PubMed ID: 21763615	2011
Morphogen gradients: from generation to interpretation. Annual review of cell and developmental biology\| PubMed ID: 21801015	2011
Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis. Genome research\| PubMed ID: 22110045	2012
Robo2 determines subtype-specific axonal projections of trigeminal sensory neurons. Development (Cambridge, England)\| PubMed ID: 22190641	2012
BAPTI and BAPTISM birthdating of neurons in zebrafish. Cold Spring Harbor protocols\| PubMed ID: 22194263	2012
Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. Developmental cell\| PubMed ID: 22421047	2012
The role of hair cells, cilia and ciliary motility in otolith formation in the zebrafish otic vesicle. Development (Cambridge, England)\| PubMed ID: 22461562	2012
Touch responsiveness in zebrafish requires voltage-gated calcium channel 2.1b. Journal of neurophysiology\| PubMed ID: 22490555	2012
Differential diffusivity of Nodal and Lefty underlies a reaction-diffusion patterning system. Science (New York, N.Y.)\| PubMed ID: 22499809	2012
Bivalent histone modifications in early embryogenesis. Current opinion in cell biology\| PubMed ID: 22513113	2012
CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms. Nature genetics\| PubMed ID: 22581229	2012
Brain-wide neuronal dynamics during motor adaptation in zebrafish. Nature\| PubMed ID: 22622571	2012
Attenuation of Notch and Hedgehog signaling is required for fate specification in the spinal cord. PLoS genetics\| PubMed ID: 22685423	2012
The tangential nucleus controls a gravito-inertial vestibulo-ocular reflex. Current biology : CB\| PubMed ID: 22704987	2012
A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research\| PubMed ID: 23382537	2013
Optical control of metabotropic glutamate receptors. Nature neuroscience\| PubMed ID: 23455609	2013
Morphogen transport. Development (Cambridge, England)\| PubMed ID: 23533171	2013
Genomics: Zebrafish earns its stripes. Nature\| PubMed ID: 23594741	2013
Specified neural progenitors sort to form sharp domains after noisy Shh signaling. Cell\| PubMed ID: 23622240	2013
Ribosome profiling reveals resemblance between long non-coding RNAs and 5' leaders of coding RNAs. Development (Cambridge, England)\| PubMed ID: 23698349	2013
Sites of action of sleep and wake drugs: insights from model organisms. Current opinion in neurobiology\| PubMed ID: 23706898	2013
Zebrabow: multispectral cell labeling for cell tracing and lineage analysis in zebrafish. Development (Cambridge, England)\| PubMed ID: 23757414	2013
Should I stay or should I go: neuromodulators of behavioral states. Cell\| PubMed ID: 23993087	2013
Canonical nucleosome organization at promoters forms during genome activation. Genome research\| PubMed ID: 24285721	2014
Toddler: an embryonic signal that promotes cell movement via Apelin receptors. Science (New York, N.Y.)\| PubMed ID: 24407481	2014
Neuropeptidergic signaling partitions arousal behaviors in zebrafish. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24573274	2014
Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs. PloS one\| PubMed ID: 24873830	2014
Neuropeptidergic control of sleep and wakefulness. Annual review of neuroscience\| PubMed ID: 25032501	2014
Obituary: Walter J. Gehring (1939-2014). Development (Cambridge, England)\| PubMed ID: 25085977	2014
Identifying (non-)coding RNAs and small peptides: Challenges and opportunities. BioEssays : news and reviews in molecular, cellular and developmental biology\| PubMed ID: 25345765	2015
High-resolution sequencing and modeling identifies distinct dynamic RNA regulatory strategies. Cell\| PubMed ID: 25497548	2014
The study of psychiatric disease genes and drugs in zebrafish. Current opinion in neurobiology\| PubMed ID: 25523356	2015