Laurent Counillon

Characterization of sabiporide, a new specific NHE-1 inhibitor exhibiting slow dissociation kinetics and cardioprotective effects.

A mechanism for the activation of the Na/H exchanger NHE-1 by cytoplasmic acidification and mitogens.

Specific Cre/Lox recombination in the mouse proximal tubule.

Cisplatin-induced apoptosis involves membrane fluidification via inhibition of NHE1 in human colon cancer cells.

5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside reduces glucose uptake via the inhibition of Na+/H+ exchanger 1 in isolated rat ventricular cardiomyocytes.

Regulation of Na+/H+ exchanger 1 allosteric balance by its localization in cholesterol- and caveolin-rich membrane microdomains.

Kinetic analysis of the regulation of the Na+/H+ exchanger NHE-1 by osmotic shocks.

On some aspects of the thermodynamic of membrane recycling mediated by fluid phase endocytosis: evaluation of published data and perspectives.

Nongenomic effects of cisplatin: acute inhibition of mechanosensitive transporters and channels without actin remodeling.

The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway.

Teaching new dogs old tricks: membrane biophysical properties in drug delivery and resistance.

On the role of the difference in surface tensions involved in the allosteric regulation of NHE-1 induced by low to mild osmotic pressure, membrane tension and lipid asymmetry.

Hypoxia promotes tumor cell survival in acidic conditions by preserving ATP levels.

NaV1.5 Na⁺ channels allosterically regulate the NHE-1 exchanger and promote the activity of breast cancer cell invadopodia.

Capturing intracellular pH dynamics by coupling its molecular mechanisms within a fully tractable mathematical model.

The intracellular Na(+)/H(+) exchanger NHE7 effects a Na(+)-coupled, but not K(+)-coupled proton-loading mechanism in endocytosis.