Shehzad Z. Sheikh

Center for Gastrointestinal Biology and Disease,
Department of Genetics,
Curriculum in Genetics and Molecular Biology

University of North Carolina at Chapel Hill

BIOGRAPHY

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PUBLICATIONS

TGF-beta signaling regulates CD8+ T cell responses to high- and low-affinity TCR interactions.

International immunology May, 2005 | Pubmed ID: 15824070

Cutting edge: IFN-gamma is a negative regulator of IL-23 in murine macrophages and experimental colitis.

Journal of immunology (Baltimore, Md. : 1950) Apr, 2010 | Pubmed ID: 20228197

Altered macrophage function contributes to colitis in mice defective in the phosphoinositide-3 kinase subunit p110δ.

Gastroenterology Nov, 2010 | Pubmed ID: 20637203

The role of the macrophage in sentinel responses in intestinal immunity.

Current opinion in gastroenterology Nov, 2010 | Pubmed ID: 20717022

Characterization of an interferon-stimulated response element (ISRE) in the Il23a promoter.

The Journal of biological chemistry Jan, 2011 | Pubmed ID: 21097874

NFIL3 is a regulator of IL-12 p40 in macrophages and mucosal immunity.

Journal of immunology (Baltimore, Md. : 1950) Apr, 2011 | Pubmed ID: 21383239

An anti-inflammatory role for carbon monoxide and heme oxygenase-1 in chronic Th2-mediated murine colitis.

Journal of immunology (Baltimore, Md. : 1950) May, 2011 | Pubmed ID: 21444764

IL-10 regulates Il12b expression via histone deacetylation: implications for intestinal macrophage homeostasis.

Journal of immunology (Baltimore, Md. : 1950) Aug, 2012 | Pubmed ID: 22786766

Carbon Monoxide and Heme Oxygenase-1 Prevent Intestinal Inflammation in Mice by Promoting Bacterial Clearance.

Gastroenterology Dec, 2012 | Pubmed ID: 23266559

NFIL3-deficient mice develop microbiota-dependent, IL-12/23-driven spontaneous colitis.

Journal of immunology (Baltimore, Md. : 1950) Feb, 2014 | Pubmed ID: 24442434

Innate PI3K p110δ regulates Th1/Th17 development and microbiota-dependent colitis.

Journal of immunology (Baltimore, Md. : 1950) Apr, 2014 | Pubmed ID: 24634494

Heme oxygenase-1 and carbon monoxide regulate intestinal homeostasis and mucosal immune responses to the enteric microbiota.

Gut microbes Mar-Apr, 2014 | Pubmed ID: 24637794

Infliximab Re-treatment in Inflammatory Bowel Disease: A Single-Center Routine Clinical Experience.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association May, 2014 | Pubmed ID: 24835819

Ancient transposable elements transformed the uterine regulatory landscape and transcriptome during the evolution of mammalian pregnancy.

Cell reports Feb, 2015 | Pubmed ID: 25640180

INSTITUTIONS

University of North Carolina at Chapel Hill

JOVE ARTICLES

Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4⁺CD45RB^high T Cells into Immunodeficient Mice

Erin C. Steinbach^1,2,

Gregory R. Gipson¹,

Shehzad Z. Sheikh^1,3,4

¹Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill,

²Department of Microbiology and Immunology, University of North Carolina at Chapel Hill,

³Department of Genetics, University of North Carolina at Chapel Hill,

⁴Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill

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Shehzad Z. Sheikh

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Center for Gastrointestinal Biology and Disease,Department of Genetics,Curriculum in Genetics and Molecular Biology

University of North Carolina at Chapel Hill

Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4+CD45RBhigh T Cells into Immunodeficient Mice

Center for Gastrointestinal Biology and Disease,
Department of Genetics,
Curriculum in Genetics and Molecular Biology

Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4⁺CD45RB^high T Cells into Immunodeficient Mice