Section of Urology,
Department of Surgery,
Section of Urology, Department of Surgery
Carrie Rinker-Schaeffer has not added Biography.
If you are Carrie Rinker-Schaeffer and would like to personalize this page please email our Author Liaison for assistance.
Functional and anatomic imaging of tumor vasculature: high-resolution MR spectroscopic imaging combined with a superparamagnetic contrast agent.
Academic radiology May, 2002 | Pubmed ID: 12019844
Highlights of the Society of Urologic Oncology meeting, June 2, 2001.
The Journal of urology Aug, 2002 | Pubmed ID: 12131337
Mitogen-activated protein kinase kinase 4 (MKK4) acts as a metastasis suppressor gene in human ovarian carcinoma.
Cancer research Nov, 2002 | Pubmed ID: 12438272
Metastasis suppression: the evolving role of metastasis suppressor genes for regulating cancer cell growth at the secondary site.
The Journal of urology Mar, 2003 | Pubmed ID: 12576866
MKK4 and metastasis suppression: a marriage of signal transduction and metastasis research.
Clinical & experimental metastasis , 2003 | Pubmed ID: 12650604
Inhibition of prostate cancer metastatic colonization by approximately 4.2 Mb of human chromosome 12.
International journal of cancer. Journal international du cancer Jan, 2004 | Pubmed ID: 14618610
A new look at an old problem: the survival and organ-specific growth of metastases.
Science's STKE : signal transduction knowledge environment Jan, 2004 | Pubmed ID: 14734785
Suppression of metastasis--a new function for known proteins.
Journal of the National Cancer Institute Mar, 2004 | Pubmed ID: 14996848
The basic biology of metastasis.
Cancer treatment and research , 2004 | Pubmed ID: 15043186
Metastasis suppressor genes: signal transduction, cross-talk and the potential for modulating the behavior of metastatic cells.
Anti-cancer drugs Jul, 2004 | Pubmed ID: 15205597
Adjunctive therapy for men with high risk localized and locally advanced prostate cancer: targeting disseminated tumor cells.
The Journal of urology Dec, 2004 | Pubmed ID: 15538203
Metastasis suppressor genes: from gene identification to protein function and regulation.
Cancer biology & therapy Aug, 2005 | Pubmed ID: 16082183
An orthotopic model of human osteosarcoma growth and spontaneous pulmonary metastasis.
Clinical & experimental metastasis , 2005 | Pubmed ID: 16170668
Suppression of metastatic colonization by the context-dependent activation of the c-Jun NH2-terminal kinase kinases JNKK1/MKK4 and MKK7.
Cancer research Dec, 2005 | Pubmed ID: 16322247
The p38 kinases MKK4 and MKK6 suppress metastatic colonization in human ovarian carcinoma.
Cancer research Feb, 2006 | Pubmed ID: 16489030
Metastasis suppressor proteins: discovery, molecular mechanisms, and clinical application.
Clinical cancer research : an official journal of the American Association for Cancer Research Jul, 2006 | Pubmed ID: 16818682
Stopping cancer before it colonizes.
Nature medicine Aug, 2006 | Pubmed ID: 16892031
Using metastasis suppressor proteins to dissect interactions among cancer cells and their microenvironment.
Cancer metastasis reviews Mar, 2008 | Pubmed ID: 18049862
Mitogen-activated protein kinase kinase 4/c-Jun NH2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell lines.
Molecular cancer research : MCR Mar, 2008 | Pubmed ID: 18337456
c-Jun NH2-terminal kinase activating kinase 1/mitogen-activated protein kinase kinase 4-mediated inhibition of SKOV3ip.1 ovarian cancer metastasis involves growth arrest and p21 up-regulation.
Cancer research Apr, 2008 | Pubmed ID: 18381422
Societal interactions in ovarian cancer metastasis: a quorum-sensing hypothesis.
Clinical & experimental metastasis , 2009 | Pubmed ID: 18516689
New paradigms for the function of JNKK1/MKK4 in controlling growth of disseminated cancer cells.
Cancer letters Dec, 2008 | Pubmed ID: 18572308
FYN is overexpressed in human prostate cancer.
BJU international Jan, 2009 | Pubmed ID: 18990162
Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs.
Science signaling , 2009 | Pubmed ID: 19861690
In vitro metastatic colonization of human ovarian cancer cells to the omentum.
Clinical & experimental metastasis Mar, 2010 | Pubmed ID: 20229256
Disrupting ovarian cancer metastatic colonization: insights from metastasis suppressor studies.
Journal of oncology , 2010 | Pubmed ID: 20300552
Thinking outside the box: using metastasis suppressors as molecular tools.
Seminars in cancer biology Apr, 2011 | Pubmed ID: 21147228
MKK4 suppresses metastatic colonization by multiple highly metastatic prostate cancer cell lines through a transient impairment in cell cycle progression.
International journal of cancer. Journal international du cancer Feb, 2012 | Pubmed ID: 21351092
Metastasis-suppressor genes in clinical practice: lost in translation?
Nature reviews. Clinical oncology Jun, 2011 | Pubmed ID: 21522123
From prostate to bone: key players in prostate cancer bone metastasis.
Cancers , 2011 | Pubmed ID: 21603150
Building on the foundation of daring hypotheses: using the MKK4 metastasis suppressor to develop models of dormancy and metastatic colonization.
FEBS letters Oct, 2011 | Pubmed ID: 21925502
Time-dependent transcriptional profiling links gene expression to mitogen-activated protein kinase kinase 4 (MKK4)-mediated suppression of omental metastatic colonization.
Clinical & experimental metastasis Jun, 2012 | Pubmed ID: 22350525
Using MKK4's metastasis suppressor function to identify and dissect cancer cell-microenvironment interactions during metastatic colonization.
Cancer metastasis reviews Dec, 2012 | Pubmed ID: 22706843
Flexible peritoneal windows for quantitative fluorescence and bioluminescence preclinical imaging.
Molecular imaging Jan-Feb, 2013 | Pubmed ID: 23348789
Milky spots promote ovarian cancer metastatic colonization of peritoneal adipose in experimental models.
The American journal of pathology Aug, 2013 | Pubmed ID: 23885715
SPOP promotes tumorigenesis by acting as a key regulatory hub in kidney cancer.
Cancer cell Apr, 2014 | Pubmed ID: 24656772
Venkatesh Krishnan1,
Robert Clark1,
Marina Chekmareva2,
Amy Johnson1,
Sophia George3,
Patricia Shaw4,
Victoria Seewaldt4,5,
Carrie Rinker-Schaeffer1
1Section of Urology, Department of Surgery, The University of Chicago,
2Department of Pathology, Robert Wood Johnson Medical School,
3Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, University Health Network,
4Department of Laboratory Medicine and Pathobiology, Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, University of Toronto, University Health Network,
5Departments of Medicine, Pharmacology, and Cancer Biology, Duke University Medical Center
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved