Arnim Pause
Goodman Cancer Research Center,
Department of Biochemistry
McGill University
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Signal transduction. Protein synthesis and oncogenesis meet again.
Science (New York, N.Y.) Oct, 2006 | Pubmed ID: 17053135
Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2002 | Pubmed ID: 12149480
Hepatitis C therapeutics: current status and emerging strategies.
Nature reviews. Drug discovery Nov, 2002 | Pubmed ID: 12415247
An NS3 serine protease inhibitor abrogates replication of subgenomic hepatitis C virus RNA.
The Journal of biological chemistry May, 2003 | Pubmed ID: 12646587
Complete translation of the hepatitis C virus genome in vitro: membranes play a critical role in the maturation of all virus proteins except for NS3.
Journal of virology Jun, 2005 | Pubmed ID: 15890926
Hepatitis C virus NS2/3 processing is required for NS3 stability and viral RNA replication.
The Journal of biological chemistry Aug, 2005 | Pubmed ID: 15980068
Characterization of a von Hippel Lindau pathway involved in extracellular matrix remodeling, cell invasion, and angiogenesis.
Cancer research Feb, 2006 | Pubmed ID: 16452184
Multiple acquired renal carcinoma tumor capabilities abolished upon silencing of ADAM17.
Cancer research Aug, 2006 | Pubmed ID: 16912185
The hepatitis C virus NS2/3 protease.
Current issues in molecular biology Jan, 2007 | Pubmed ID: 17263146
The RNA-binding protein HuR promotes cell migration and cell invasion by stabilizing the beta-actin mRNA in a U-rich-element-dependent manner.
Molecular and cellular biology Aug, 2007 | Pubmed ID: 17548472
eEF1A is a novel component of the mammalian nuclear protein export machinery.
Molecular biology of the cell Dec, 2008 | Pubmed ID: 18799616
Investigation of a role for lysine residues in non-structural proteins 2 and 2/3 of the hepatitis C virus for their degradation and virus assembly.
The Journal of general virology May, 2009 | Pubmed ID: 19264595
HD-PTP is a catalytically inactive tyrosine phosphatase due to a conserved divergence in its phosphatase domain.
PloS one , 2009 | Pubmed ID: 19340315
Expression analysis and essential role of the putative tyrosine phosphatase His-domain-containing protein tyrosine phosphatase (HD-PTP).
The International journal of developmental biology , 2009 | Pubmed ID: 19378249
Novel bisphosphonate inhibitors of the human farnesyl pyrophosphate synthase.
Bioorganic & medicinal chemistry letters Oct, 2010 | Pubmed ID: 20801032
The subcellular localization of the hepatitis C virus non-structural protein NS2 is regulated by an ion channel-independent function of the p7 protein.
The Journal of general virology Apr, 2011 | Pubmed ID: 21177929
An oxygen-regulated switch in the protein synthesis machinery.
Nature Jun, 2012 | Pubmed ID: 22678294
Birt-Hogg-Dubé: tumour suppressor function and signalling dynamics central to folliculin.
Familial cancer Sep, 2013 | Pubmed ID: 23096221
Pseudophosphatases: methods of analysis and physiological functions.
Methods (San Diego, Calif.) Jan, 2014 | Pubmed ID: 24064037
mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation.
Cell metabolism Nov, 2013 | Pubmed ID: 24206664
Canadian guideline on genetic screening for hereditary renal cell cancers.
Canadian Urological Association journal = Journal de l'Association des urologues du Canada Sep-Oct, 2013 | Pubmed ID: 24319509
The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation.
The Journal of clinical investigation Jun, 2014 | Pubmed ID: 24762438
Folliculin regulates ampk-dependent autophagy and metabolic stress survival.
PLoS genetics Apr, 2014 | Pubmed ID: 24763318
The ever-evolving role of mTOR in translation.
Seminars in cell & developmental biology Dec, 2014 | Pubmed ID: 25263010
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