Neurodegenerative Diseases Unit
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Transmissible spongiform encephalopathy diagnosis using PrPsc immunohistochemistry on fixed but previously frozen brain samples.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society May, 2002 | Pubmed ID: 11967272
Identification of inter-species transmission of prion strains.
Journal of neuropathology and experimental neurology May, 2002 | Pubmed ID: 12025940
Mouse models of prion disease transmission.
Trends in molecular medicine Oct, 2002 | Pubmed ID: 12383773
Comparison of abnormal prion protein glycoform patterns from transmissible spongiform encephalopathy agent-infected deer, elk, sheep, and cattle.
Journal of virology Dec, 2002 | Pubmed ID: 12414979
Detection of bovine spongiform encephalopathy, ovine scrapie prion-related protein (PrPSc) and normal PrPc by monoclonal antibodies raised to copper-refolded prion protein.
The Biochemical journal Feb, 2003 | Pubmed ID: 12429022
How the surveillance system may bias the results of analytical epidemiological studies on BSE: prevalence among dairy versus beef suckler cattle breeds in France.
Veterinary research Mar-Apr, 2003 | Pubmed ID: 12657210
First case of feline spongiform encephalopathy in a captive cheetah born in France: PrP(sc) analysis in various tissues revealed unexpected targeting of kidney and adrenal gland.
Histochemistry and cell biology May, 2003 | Pubmed ID: 12783238
Neuropathological characterisation of French bovine spongiform encephalopathy cases.
Histochemistry and cell biology Dec, 2003 | Pubmed ID: 14624299
Distinct molecular phenotypes in bovine prion diseases.
EMBO reports Jan, 2004 | Pubmed ID: 14710195
Comparative molecular analysis of the abnormal prion protein in field scrapie cases and experimental bovine spongiform encephalopathy in sheep by use of Western blotting and immunohistochemical methods.
Journal of virology Apr, 2004 | Pubmed ID: 15016886
Molecular analysis of the protease-resistant prion protein in scrapie and bovine spongiform encephalopathy transmitted to ovine transgenic and wild-type mice.
Journal of virology Jun, 2004 | Pubmed ID: 15163717
Automatic quantitation of vacuolar lesions in the brain of mice infected with transmissible spongiform encephalopathies.
Journal of virological methods Mar, 2005 | Pubmed ID: 15664069
BSE agent signatures in a goat.
The Veterinary record Apr, 2005 | Pubmed ID: 15833975
An alternative pretreatment procedure in animal transmissible spongiform encephalopathies diagnosis using PrPsc immunohistochemistry.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society Oct, 2005 | Pubmed ID: 16009961
A newly identified type of scrapie agent can naturally infect sheep with resistant PrP genotypes.
Proceedings of the National Academy of Sciences of the United States of America Nov, 2005 | Pubmed ID: 16239348
Origin of bovine spongiform encephalopathy.
Lancet Jan, 2006 | Pubmed ID: 16443028
Diagnosis of transmissible spongiform encephalopathies in animals: a review.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc Nov, 2005 | Pubmed ID: 16475509
PET-blot analysis contributes to BSE strain recognition in C57Bl/6 mice.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society Oct, 2006 | Pubmed ID: 16735593
PrP(d) accumulation in organs of ARQ/ARQ sheep experimentally infected with BSE by peripheral routes.
Acta biochimica Polonica , 2006 | Pubmed ID: 16770445
Transmission of new bovine prion to mice.
Emerging infectious diseases Jul, 2006 | Pubmed ID: 16836832
BSE inoculation to prion diseases-resistant sheep reveals tricky silent carriers.
Biochemical and biophysical research communications Dec, 2006 | Pubmed ID: 17049491
Isolation from cattle of a prion strain distinct from that causing bovine spongiform encephalopathy.
PLoS pathogens Oct, 2006 | Pubmed ID: 17054396
Bovine spongiform encephalopathy agent in a prion protein (PrP)ARR/ARR genotype sheep after peripheral challenge: complete immunohistochemical analysis of disease-associated PrP and transmission studies to ovine-transgenic mice.
The Journal of infectious diseases Apr, 2007 | Pubmed ID: 17330789
Peripheral circulation of the prion infectious agent in transgenic mice expressing the ovine prion protein gene in neurons only.
The Journal of infectious diseases Apr, 2007 | Pubmed ID: 17330790
Scrapie strain transmission studies in ovine PrP transgenic mice reveal dissimilar susceptibility.
Histochemistry and cell biology May, 2007 | Pubmed ID: 17361441
Similar biochemical signatures and prion protein genotypes in atypical scrapie and Nor98 cases, France and Norway.
Emerging infectious diseases Jan, 2007 | Pubmed ID: 17370516
Molecular behaviors of "CH1641-like" sheep scrapie isolates in ovine transgenic mice (TgOvPrP4).
Journal of virology Jul, 2007 | Pubmed ID: 17442721
Molecular discrimination of atypical bovine spongiform encephalopathy strains from a geographical region spanning a wide area in Europe.
Journal of clinical microbiology Jun, 2007 | Pubmed ID: 17442800
A bovine prion acquires an epidemic bovine spongiform encephalopathy strain-like phenotype on interspecies transmission.
The Journal of neuroscience : the official journal of the Society for Neuroscience Jun, 2007 | Pubmed ID: 17596445
Biochemical identification of bovine spongiform encephalopathies in cattle.
Acta neuropathologica Nov, 2007 | Pubmed ID: 17668226
Classic scrapie in sheep with the ARR/ARR prion genotype in Germany and France.
Emerging infectious diseases Aug, 2007 | Pubmed ID: 17953092
Bovine spongiform encephalopathy in Sweden: an H-type variant.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc Jan, 2008 | Pubmed ID: 18182501
Phenotypic similarity of transmissible mink encephalopathy in cattle and L-type bovine spongiform encephalopathy in a mouse model.
Emerging infectious diseases Dec, 2007 | Pubmed ID: 18258040
Atypical bovine spongiform encephalopathies, France, 2001-2007.
Emerging infectious diseases Feb, 2008 | Pubmed ID: 18258124
Association of a bovine prion gene haplotype with atypical BSE.
PloS one , 2008 | Pubmed ID: 18350166
Rapid typing of transmissible spongiform encephalopathy strains with differential ELISA.
Emerging infectious diseases Apr, 2008 | Pubmed ID: 18394279
A C-terminal protease-resistant prion fragment distinguishes ovine "CH1641-like" scrapie from bovine classical and L-Type BSE in ovine transgenic mice.
PLoS pathogens , 2008 | Pubmed ID: 18769714
Size effects in mechanical deformation and fracture of cantilevered silicon nanowires.
Nano letters Feb, 2009 | Pubmed ID: 19159318
H-type bovine spongiform encephalopathy: complex molecular features and similarities with human prion diseases.
Prion Jan-Mar, 2007 | Pubmed ID: 19164888
Toxic effects of intracerebral PrP antibody administration during the course of BSE infection in mice.
Prion Jul-Sep, 2007 | Pubmed ID: 19164902
Altered expression of CRMPs in the brain of bovine spongiform encephalopathy-infected mice during disease progression.
Brain research Mar, 2009 | Pubmed ID: 19401179
Self-assembling study of a cylinder-forming block copolymer via a nucleation-growth mechanism.
Nanotechnology Mar, 2009 | Pubmed ID: 19417493
Possible case of maternal transmission of feline spongiform encephalopathy in a captive cheetah.
PloS one , 2009 | Pubmed ID: 19738899
Transmissibility of atypical scrapie in ovine transgenic mice: major effects of host prion protein expression and donor prion genotype.
PloS one , 2009 | Pubmed ID: 19806224
Strain-specific proteolytic processing of the prion protein in prion diseases of ruminants transmitted in ovine transgenic mice.
The Journal of general virology Feb, 2010 | Pubmed ID: 19828761
Prions of ruminants show distinct splenotropisms in an ovine transgenic mouse model.
PloS one , 2010 | Pubmed ID: 20436680
Is the presence of abnormal prion protein in the renal glomeruli of feline species presenting with FSE authentic?
BMC veterinary research , 2010 | Pubmed ID: 20684771
Production of a monoclonal antibody, against human α-synuclein, in a subpopulation of C57BL/6J mice, presenting a deletion of the α-synuclein locus.
Journal of neuroscience methods Oct, 2010 | Pubmed ID: 20709102
Strain-specific barriers against bovine prions in hamsters.
Journal of virology Feb, 2011 | Pubmed ID: 21123380
Molecular typing of protease-resistant prion protein in transmissible spongiform encephalopathies of small ruminants, France, 2002-2009.
Emerging infectious diseases Jan, 2011 | Pubmed ID: 21192855
Emergence of classical BSE strain properties during serial passages of H-BSE in wild-type mice.
PloS one , 2011 | Pubmed ID: 21264286
An improved AFM cross-sectional method for piezoelectric nanostructures properties investigation: application to GaN nanowires.
Nanotechnology Mar, 2011 | Pubmed ID: 21289392
Molecular discrimination of sheep bovine spongiform encephalopathy from scrapie.
Emerging infectious diseases Apr, 2011 | Pubmed ID: 21470463
Transmission of prion strains in a transgenic mouse model overexpressing human A53T mutated α-synuclein.
Journal of neuropathology and experimental neurology May, 2011 | Pubmed ID: 21487306
Atypical prion diseases in humans and animals.
Topics in current chemistry , 2011 | Pubmed ID: 21598097
Growth and characterization of gold catalyzed SiGe nanowires and alternative metal-catalyzed Si nanowires.
Nanoscale research letters , 2011 | Pubmed ID: 21711709
Histopathological studies of "CH1641-like" scrapie sources versus classical scrapie and BSE transmitted to ovine transgenic mice (TgOvPrP4).
PloS one , 2011 | Pubmed ID: 21765939
Prion-like acceleration of a synucleinopathy in a transgenic mouse model.
Neurobiology of aging Sep, 2012 | Pubmed ID: 21813214
Classical bovine spongiform encephalopathy by transmission of H-type prion in homologous prion protein context.
Emerging infectious diseases Sep, 2011 | Pubmed ID: 21888788
Selection of distinct strain phenotypes in mice infected by ovine natural scrapie isolates similar to CH1641 experimental scrapie.
Journal of neuropathology and experimental neurology Feb, 2012 | Pubmed ID: 22249459
Oral transmission of L-type bovine spongiform encephalopathy in primate model.
Emerging infectious diseases Jan, 2012 | Pubmed ID: 22261009
Bovine PrP expression levels in transgenic mice influence transmission characteristics of atypical bovine spongiform encephalopathy.
The Journal of general virology May, 2012 | Pubmed ID: 22302882
An antibody with high reactivity for disease-associated α-synuclein reveals extensive brain pathology.
Acta neuropathologica Jul, 2012 | Pubmed ID: 22370907
Chronic wasting disease and atypical forms of bovine spongiform encephalopathy and scrapie are not transmissible to mice expressing wild-type levels of human prion protein.
The Journal of general virology Jul, 2012 | Pubmed ID: 22495232
All major prion types recognised by a multiplex immunofluorometric assay for disease screening and confirmation in sheep.
Journal of immunological methods Jun, 2012 | Pubmed ID: 22498749
Differentiation of prions from L-type BSE versus sporadic Creutzfeldt-Jakob disease.
Emerging infectious diseases Dec, 2012 | Pubmed ID: 23171544
Unique properties of the classical bovine spongiform encephalopathy strain and its emergence from H-type bovine spongiform encephalopathy substantiated by VM transmission studies.
Journal of neuropathology and experimental neurology Mar, 2013 | Pubmed ID: 23399901
Control of 10 nm scale cylinder orientation in self-organized sugar-based block copolymer thin films.
Nanoscale Apr, 2013 | Pubmed ID: 23443358
Specific pesticide-dependent increases in α-synuclein levels in human neuroblastoma (SH-SY5Y) and melanoma (SK-MEL-2) cell lines.
Toxicological sciences : an official journal of the Society of Toxicology Jun, 2013 | Pubmed ID: 23535362
Sequential growth of bistable copper-molybdenum coordination nanolayers on inorganic surfaces.
Dalton transactions (Cambridge, England : 2003) Jun, 2013 | Pubmed ID: 23570039
Stability properties of PrP(Sc) from cattle with experimental transmissible spongiform encephalopathies: use of a rapid whole homogenate, protease-free assay.
BMC veterinary research , 2013 | Pubmed ID: 23945217
Presence of subclinical infection in gene-targeted human prion protein transgenic mice exposed to atypical bovine spongiform encephalopathy.
The Journal of general virology Dec, 2013 | Pubmed ID: 24045112
L-type bovine spongiform encephalopathy in genetically susceptible and resistant sheep: changes in prion strain or phenotypic plasticity of the disease-associated prion protein?
The Journal of infectious diseases Mar, 2014 | Pubmed ID: 24218507
Alpha-synuclein spreading in M83 mice brain revealed by detection of pathological α-synuclein by enhanced ELISA.
Acta neuropathologica communications , 2014 | Pubmed ID: 24624994
Distinct transmissibility features of TSE sources derived from ruminant prion diseases by the oral route in a transgenic mouse model (TgOvPrP4) overexpressing the ovine prion protein.
PloS one , 2014 | Pubmed ID: 24797075
Composition-dependent interfacial abruptness in Au-catalyzed Si(1-x)Ge(x)/Si/Si(1-x)Ge(x) nanowire heterostructures.
Nano letters Sep, 2014 | Pubmed ID: 25118977
Molecular modeling of prion transmission to humans.
Viruses Oct, 2014 | Pubmed ID: 25279820
Multimode silicon nanowire transistors.
Nano letters Nov, 2014 | Pubmed ID: 25303290
A variety of pesticides trigger in vitro α-synuclein accumulation, a key event in Parkinson's disease.
Archives of toxicology Oct, 2014 | Pubmed ID: 25326819
Early and persistent expression of phosphorylated α-synuclein in the enteric nervous system of A53T mutant human α-synuclein transgenic mice.
Journal of neuropathology and experimental neurology Dec, 2014 | Pubmed ID: 25383638
Binding of the PET radiotracer [¹⁸F]BF227 does not reflect the presence of alpha-synuclein aggregates in transgenic mice.
Current Alzheimer research , 2014 | Pubmed ID: 25387331
Adjustable continence therapy (ProACT™) after male sling failure for patients with post-radical prostatectomy urinary incontinence: a prospective study with one-year follow-up.
World journal of urology Nov, 2014 | Pubmed ID: 25416348
Percolating silicon nanowire networks with highly reproducible electrical properties.
Nanotechnology Jan, 2015 | Pubmed ID: 25483713
Sheep prions with molecular properties intermediate between classical scrapie, BSE and CH1641-scrapie.
Prion , 2014 | Pubmed ID: 25522672
Dominique Bétemps1,
Jérémy Verchère1,
Anne-Laure Mougenot2,
Ingolf Lachmann3,
Eric Morignat4,
Emilie Antier5,
Latifa Lakhdar5,
Stéphane Legastelois2,
Thierry Baron1
1Neurodegenerative Diseases Unit, ANSES - French Agency for Food, Environmental and Occupational Health & Safety,
2, Indicia Production,
3, AJ Roboscreen GmbH,
4Epidemiology Unit, ANSES - French Agency for Food, Environmental and Occupational Health & Safety,
5Experimental Facilities, ANSES - French Agency for Food, Environmental and Occupational Health & Safety
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