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Interactions between the megakaryocyte/platelet-specific beta1 tubulin and the secretory leukocyte protease inhibitor SLPI suggest a role for regulated proteolysis in platelet functions.
Blood Dec, 2004 | Pubmed ID: 15315966
Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis.
Blood May, 2006 | Pubmed ID: 16434494
RanBP10 is a cytoplasmic guanine nucleotide exchange factor that modulates noncentrosomal microtubules.
The Journal of biological chemistry May, 2008 | Pubmed ID: 18347012
The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2.
The Journal of biological chemistry May, 2008 | Pubmed ID: 18411277
The emerging role of miR-200 family of microRNAs in epithelial-mesenchymal transition and cancer metastasis.
RNA biology Jul-Sep, 2008 | Pubmed ID: 19182522
Imaging transforming growth factor-beta signaling dynamics and therapeutic response in breast cancer bone metastasis.
Nature medicine Aug, 2009 | Pubmed ID: 19597504
Targeting the transforming growth factor-beta signalling pathway in metastatic cancer.
European journal of cancer (Oxford, England : 1990) May, 2010 | Pubmed ID: 20307969
MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells.
Journal of translational medicine , 2011 | Pubmed ID: 21426561
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization.
Nature medicine Sep, 2011 | Pubmed ID: 21822286
Isocitrate dehydrogenase (IDH) mutations promote a reversible ZEB1/microRNA (miR)-200-dependent epithelial-mesenchymal transition (EMT).
The Journal of biological chemistry Dec, 2012 | Pubmed ID: 23038259
An F876L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (enzalutamide).
Cancer discovery Sep, 2013 | Pubmed ID: 23842682
H3 Biomedicine
Manav Korpal1,
Jacob Feala1,
Xiaoling Puyang1,
Jian Zou1,
Alex H. Ramos2,
Jeremy Wu1,
Timm Baumeister1,
Lihua Yu1,
Markus Warmuth1,
Ping Zhu1
1, H3 Biomedicine,
2, Massachusetts General Hospital
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