Christian Berens

Tetracycline derivatives: alternative effectors for Tet transregulators.

Conditional gene expression by controlling translation with tetracycline-binding aptamers.

Conditional cell suicide using dox-dependent caspase-2 expression.

Single-chain Tet transregulators.

Gene regulation by tetracyclines. Constraints of resistance regulation in bacteria shape TetR for application in eukaryotes.

Comparison of tetracycline and tigecycline binding to ribosomes mapped by dimethylsulphate and drug-directed Fe2+ cleavage of 16S rRNA.

A theophylline responsive riboswitch based on helix slipping controls gene expression in vivo.

Transactivator mutants with altered effector specificity allow selective regulation of two genes by tetracycline variants.

A short autonomous repression motif is located within the N-terminal domain of CTCF.

Gene regulation by tetracyclines.

Inducible DNA-loop formation blocks transcriptional activation by an SV40 enhancer.

An optimized conditional suicide switch using doxycycline-dependent expression of human tBid.

A peptide triggers allostery in tet repressor by binding to a unique site.

Development of a transactivator in hepatoma cells that allows expression of phase I, phase II, and chemical defense genes.

Stringent doxycycline-dependent control of gene activities using an episomal one-vector system.

Reproducible doxycycline-inducible transgene expression at specific loci generated by Cre-recombinase mediated cassette exchange.

A gene regulation system with four distinct expression levels.

Subtype selective tetracycline agonists and their application for a two-stage regulatory system.

Random insertion of a TetR-inducing peptide tag into Escherichia coli proteins allows analysis of protein levels by induction of reporter gene expression.

Improved single-chain transactivators of the Tet-On gene expression system.

How an agonist peptide mimics the antibiotic tetracycline to induce Tet-repressor.

Efficient and exclusive induction of Tet repressor by the oligopeptide Tip results from co-variation of their interaction site.

Interaction between HMGA1a and the origin recognition complex creates site-specific replication origins.

Functionally important residues of the Tet repressor inducing peptide TIP determined by a complete mutational analysis.

An RNA aptamer that induces transcription.

Regulation of boundary cap neural crest stem cell differentiation after transplantation.

Adjusting transgene expression levels in lymphocytes with a set of inducible promoters.

Anhydrotetracycline-peptide conjugates as representatives for ligand-based transactivating systems.

A suicide gene approach using the human pro-apoptotic protein tBid inhibits HIV-1 replication.

Forced Runx1 expression in human neural stem/progenitor cells transplanted to the rat dorsal root ganglion cavity results in extensive axonal growth specifically from spinal cord-derived neurospheres.

A novel MCF-10A line allowing conditional oncogene expression in 3D culture.

An exclusive α/β code directs allostery in TetR-peptide complexes.

Short peptides act as inducers, anti-inducers and corepressors of Tet repressor.

Apoptosis induction and tumor cell repopulation: the yin and yang of radiotherapy.

A recombinant triplebody with specificity for CD19 and HLA-DR mediates preferential binding to antigen double-positive cells by dual-targeting.

Guiding differentiation of stem cells in vivo by tetracycline-controlled expression of key transcription factors.

Promoter strength driving TetR determines the regulatory properties of Tet-controlled expression systems.

The Coxiella burnetii type IV secretion system substrate CaeB inhibits intrinsic apoptosis at the mitochondrial level.

Model systems for rapid and slow induction of apoptosis obtained by inducible expression of pro-apoptotic proteins.

UVB-irradiated apoptotic cells induce accelerated growth of co-implanted viable tumor cells in immune competent mice.

Colourful death: six-parameter classification of cell death by flow cytometry--dead cells tell tales.

Recognition of operator DNA by Tet repressor.

Autoimmunity vs. cancer: predator vs. alien?

Navigation to the graveyard-induction of various pathways of necrosis and their classification by flow cytometry.

AP4 is a mediator of epithelial-mesenchymal transition and metastasis in colorectal cancer.

Antiapoptotic activity of Coxiella burnetii effector protein AnkG is controlled by p32-dependent trafficking.

An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity.

A novel TetR-regulating peptide turns off rtTA-mediated activation of gene expression.

Tumor immunotherapy: lessons from autoimmunity.

tLivin displays flexibility by promoting alternative cell death mechanisms.

The role of dead cell clearance in the etiology and pathogenesis of systemic lupus erythematosus: dendritic cells as potential targets.

Riboswitch engineering - making the all-important second and third steps.

Tet-Trap, a genetic approach to the identification of bacterial RNA thermometers: application to Pseudomonas aeruginosa.

The progression of cell death affects the rejection of allogeneic tumors in immune-competent mice - implications for cancer therapy.

RNA aptamers as genetic control devices: the potential of riboswitches as synthetic elements for regulating gene expression.

Apoptotic cell clearance and its role in the origin and resolution of chronic inflammation.