Jinzi Zheng

Techna Institute and Radiation Medicine Program,
Princess Margaret Cancer Center,
STTARR Innovation Center,
Techna Institute and Radiation Medicine Program, Princess Margaret Cancer Center

University Health Network

BIOGRAPHY

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PUBLICATIONS

Multimodal contrast agent for combined computed tomography and magnetic resonance imaging applications.

Investigative radiology Mar, 2006 | Pubmed ID: 16481918

In vivo performance of a liposomal vascular contrast agent for CT and MR-based image guidance applications.

Pharmaceutical research Jun, 2007 | Pubmed ID: 17373581

Quantitative CT imaging of the spatial and temporal distribution of liposomes in a rabbit tumor model.

Molecular pharmaceutics Mar-Apr, 2009 | Pubmed ID: 19298061

Targeting focal adhesion kinase with dominant-negative FRNK or Hsp90 inhibitor 17-DMAG suppresses tumor growth and metastasis of SiHa cervical xenografts.

Cancer research Jun, 2009 | Pubmed ID: 19458065

Liposome contrast agent for CT-based detection and localization of neoplastic and inflammatory lesions in rabbits: validation with FDG-PET and histology.

Contrast media & molecular imaging May-Jun, 2010 | Pubmed ID: 20586032

Differential expression of the 18 kDa translocator protein (TSPO) by neoplastic and inflammatory cells in mouse tumors of breast cancer.

Molecular pharmaceutics Jun, 2011 | Pubmed ID: 21417480

APN/CD13-targeting as a strategy to alter the tumor accumulation of liposomes.

Journal of controlled release : official journal of the Controlled Release Society Sep, 2011 | Pubmed ID: 21640146

The translocator protein ligand [¹⁸F]DPA-714 images glioma and activated microglia in vivo.

European journal of nuclear medicine and molecular imaging May, 2012 | Pubmed ID: 22270507

A novel minimally invasive technique to create a rabbit VX2 lung tumor model for nano-sized image contrast and interventional studies.

PloS one , 2013 | Pubmed ID: 23840673

The translocator protein radioligand 18F-DPA-714 monitors antitumor effect of erufosine in a rat 9L intracranial glioma model.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine Dec, 2013 | Pubmed ID: 24212976

A mathematical model of the enhanced permeability and retention effect for liposome transport in solid tumors.

PloS one , 2013 | Pubmed ID: 24312530

Heat-activated thermosensitive liposomal cisplatin (HTLC) results in effective growth delay of cervical carcinoma in mice.

Journal of controlled release : official journal of the Controlled Release Society Mar, 2014 | Pubmed ID: 24440663

A gradient-loadable (64)Cu-chelator for quantifying tumor deposition kinetics of nanoliposomal therapeutics by positron emission tomography.

Nanomedicine : nanotechnology, biology, and medicine Jan, 2015 | Pubmed ID: 25200610

Whole-body organ-level and kidney micro-dosimetric evaluations of (64)Cu-loaded HER2/ErbB2-targeted liposomal doxorubicin ((64)Cu-MM-302) in rodents and primates.

EJNMMI research , 2015 | Pubmed ID: 25918676

Contrast Agent Mass Spectrometry Imaging Reveals Tumor Heterogeneity.

Analytical chemistry Aug, 2015 | Pubmed ID: 26138213

Cyclophosphamide-Mediated Tumor Priming for Enhanced Delivery and Antitumor Activity of HER2-Targeted Liposomal Doxorubicin (MM-302).

Molecular cancer therapeutics Sep, 2015 | Pubmed ID: 26162690

Evaluation of PET Imaging Performance of the TSPO Radioligand [(18)F]DPA-714 in Mouse and Rat Models of Cancer and Inflammation.

Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging Jul, 2015 | Pubmed ID: 26194010

A multimodal nano agent for image-guided cancer surgery.

Biomaterials Oct, 2015 | Pubmed ID: 26218742

Longitudinal tumor hypoxia imaging with [(18)F]FAZA-PET provides early prediction of nanoliposomal irinotecan (nal-IRI) treatment activity.

EJNMMI research Dec, 2015 | Pubmed ID: 26481012

Ambient Mass Spectrometry Imaging with Picosecond Infrared Laser Ablation Electrospray Ionization (PIR-LAESI).

Analytical chemistry Nov, 2015 | Pubmed ID: 26561279

INSTITUTIONS

University Health Network

Princess Margaret Cancer Centre

University of Toronto

University Health Network

JOVE ARTICLES

Custom-designed Laser-based Heating Apparatus for Triggered Release of Cisplatin from Thermosensitive Liposomes with Magnetic Resonance Image Guidance

Yannan N. Dou¹,

Robert A. Weersink^2,5,

Warren D. Foltz^5,6,

Jinzi Zheng^5,6,

Naz Chaudary⁷,

David A. Jaffray^2,3,4,5,6,

Christine Allen¹

¹Leslie Dan Faculty of Pharmacy, University of Toronto,

²Department of Radiation Oncology, University of Toronto,

³Medical Biophysics, University of Toronto,

⁴Institute of Biomaterials & Biomedical Engineering, University of Toronto,

⁵Techna Institute and Radiation Medicine Program, Princess Margaret Cancer Center, University Health Network,

⁶STTARR Innovation Center, University Health Network,

⁷Ontario Cancer Institute, University Health Network

Bioengineering

Spatial Measurements of Perfusion, Interstitial Fluid Pressure and Liposomes Accumulation in Solid Tumors

Shawn Stapleton^1,2,3,

Daniel Mirmilshteyn²,

Jinzi Zheng^3,4,

Christine Allen^2,4,5,

David A. Jaffray^1,2,3,4,5,6

¹Department of Medical Biophysics, University of Toronto,

²Leslie Dan Faculty of Pharmacy, University of Toronto,

³STTARR Innovation Centre, Princess Margaret Cancer Centre,

⁴Institute of Biomaterials and Biomedical Engineering, University of Toronto,

⁵Techna Institute, University Health Network,

⁶Radiation Medicine Program, Princess Margaret Cancer Centre

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Jinzi Zheng

Techna Institute and Radiation Medicine Program,Princess Margaret Cancer Center,STTARR Innovation Center,Techna Institute and Radiation Medicine Program, Princess Margaret Cancer Center

University Health Network

Custom-designed Laser-based Heating Apparatus for Triggered Release of Cisplatin from Thermosensitive Liposomes with Magnetic Resonance Image Guidance

Spatial Measurements of Perfusion, Interstitial Fluid Pressure and Liposomes Accumulation in Solid Tumors

Techna Institute and Radiation Medicine Program,
Princess Margaret Cancer Center,
STTARR Innovation Center,
Techna Institute and Radiation Medicine Program, Princess Margaret Cancer Center