Timothy Cardozo

Eosinophilic fasciitis.

The SCF ubiquitin ligase: insights into a molecular machine.

Systematic analysis and nomenclature of mammalian F-box proteins.

Androgen receptor mutations identified in prostate cancer and androgen insensitivity syndrome display aberrant ART-27 coactivator function.

Druggability of SCF ubiquitin ligase-protein interfaces.

Distinct sequence patterns characterize the V3 region of HIV type 1 gp120 from subtypes A and C.

Modeling the interaction between aldolase and the thrombospondin-related anonymous protein, a key connection of the malaria parasite invasion machinery.

Structural basis for coreceptor selectivity by the HIV type 1 V3 loop.

Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite.

Farnesyl pyrophosphate is a novel transcriptional activator for a subset of nuclear hormone receptors.

Wrenches in the works: drug discovery targeting the SCF ubiquitin ligase and APC/C complexes.

Control of chromosome stability by the beta-TrCP-REST-Mad2 axis.

Worldwide distribution of HIV type 1 epitopes recognized by human anti-V3 monoclonal antibodies.

Recombinant derivatives of botulinum neurotoxin A engineered for trafficking studies and neuronal delivery.

Characterization of a dominant-active STAT that promotes tumorigenesis in Drosophila.

Structural conservation predominates over sequence variability in the crown of HIV type 1's V3 loop.

Structure-function relationships of HIV-1 envelope sequence-variable regions refocus vaccine design.

Conserved structural elements in the V3 crown of HIV-1 gp120.

Structure-guided design and immunological characterization of immunogens presenting the HIV-1 gp120 V3 loop on a CTB scaffold.

Nuclear receptor engineering based on novel structure activity relationships revealed by farnesyl pyrophosphate.

Structural determinants of PERK inhibitor potency and selectivity.

Comparative magnitude of cross-strain conservation of HIV variable loop neutralization epitopes.

Quantitative assessment of masking of neutralization epitopes in HIV-1.

An RNAi-based chemical genetic screen identifies three small-molecule inhibitors of the Wnt/wingless signaling pathway.

Cross-clade HIV-1 neutralizing antibodies induced with V3-scaffold protein immunogens following priming with gp120 DNA.

Tagetitoxin inhibits RNA polymerase through trapping of the trigger loop.

Indirect detection of an epitope-specific response to HIV-1 gp120 immunization in human subjects.

Human anti-V3 HIV-1 monoclonal antibodies encoded by the VH5-51/VL lambda genes define a conserved antigenic structure.

Recovering protein-protein and domain-domain interactions from aggregation of IP-MS proteomics of coregulator complexes.