Yi-Chin Toh

Department of Biomedical Engineering,
Singapore Institute of Neurotechnology (SINAPSE)

National University of Singapore

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PUBLICATIONS

Application of a polyelectrolyte complex coacervation method to improve seeding efficiency of bone marrow stromal cells in a 3D culture system.

Biomaterials Jul, 2005 | Pubmed ID: 15664642

A configurable three-dimensional microenvironment in a microfluidic channel for primary hepatocyte culture.

Assay and drug development technologies Apr, 2005 | Pubmed ID: 15871691

A novel 3D mammalian cell perfusion-culture system in microfluidic channels.

Lab on a chip Mar, 2007 | Pubmed ID: 17330160

A practical guide to microfluidic perfusion culture of adherent mammalian cells.

Lab on a chip Jun, 2007 | Pubmed ID: 17538709

Integrating sensitive quantification of hepatic metabolic functions by capillary electrophoresis with laser-induced fluorescence detection.

The Analyst Mar, 2008 | Pubmed ID: 18299746

A gel-free 3D microfluidic cell culture system.

Biomaterials Aug, 2008 | Pubmed ID: 18455231

Dendrimer hydrazides as multivalent transient inter-cellular linkers.

Biomaterials Sep, 2008 | Pubmed ID: 18554713

Microfabricated silicon nitride membranes for hepatocyte sandwich culture.

Biomaterials Oct, 2008 | Pubmed ID: 18635259

The controlled presentation of TGF-beta1 to hepatocytes in a 3D-microfluidic cell culture system.

Biomaterials Aug, 2009 | Pubmed ID: 19394078

A microfluidic 3D hepatocyte chip for drug toxicity testing.

Lab on a chip Jul, 2009 | Pubmed ID: 19568671

Advancing stem cell research with microtechnologies: opportunities and challenges.

Integrative biology : quantitative biosciences from nano to macro Aug, 2010 | Pubmed ID: 20593104

Fluid shear stress primes mouse embryonic stem cells for differentiation in a self-renewing environment via heparan sulfate proteoglycans transduction.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology Apr, 2011 | Pubmed ID: 21183594

Leveraging on being small-Singapore's strategy to catalyze integrative innovations.

Lab on a chip Jun, 2011 | Pubmed ID: 21573313

Spatially organized in vitro models instruct asymmetric stem cell differentiation.

Integrative biology : quantitative biosciences from nano to macro Dec, 2011 | Pubmed ID: 22028041

Mechanical compaction directly modulates the dynamics of bile canaliculi formation.

Integrative biology : quantitative biosciences from nano to macro Feb, 2013 | Pubmed ID: 23233209

Scalable cell alignment on optical media substrates.

Biomaterials Jul, 2013 | Pubmed ID: 23601659

Scalable alignment of three-dimensional cellular constructs in a microfluidic chip.

Lab on a chip Oct, 2013 | Pubmed ID: 23969512

Modulation of integrin and E-cadherin-mediated adhesions to spatially control heterogeneity in human pluripotent stem cell differentiation.

Biomaterials May, 2015 | Pubmed ID: 25736499

A method for human teratogen detection by geometrically confined cell differentiation and migration.

Scientific reports , 2015 | Pubmed ID: 25966467

Corrigendum: A method for human teratogen detection by geometrically confined cell differentiation and migration.

Scientific reports , 2015 | Pubmed ID: 26237348

Cost-effective differentiation of hepatocyte-like cells from human pluripotent stem cells using small molecules.

Biomaterials Nov, 2015 | Pubmed ID: 26310107

Stencil Micropatterning for Spatial Control of Human Pluripotent Stem Cell Fate Heterogeneity.

Methods in molecular biology (Clifton, N.J.) Apr, 2016 | Pubmed ID: 27032943

Functionally Enhanced Human Stem Cell Derived Hepatocytes in Galactosylated Cellulosic Sponges for Hepatotoxicity Testing.

Molecular pharmaceutics Jun, 2016 | Pubmed ID: 27157693

INSTITUTIONS

National University of Singapore

JOVE ARTICLES

Stencil Micropatterning of Human Pluripotent Stem Cells for Probing Spatial Organization of Differentiation Fates

Geetika Sahni^*,1,

Jun Yuan^*,1,

Yi-Chin Toh^1,2

¹Department of Biomedical Engineering, National University of Singapore,

²Singapore Institute of Neurotechnology (SINAPSE), National University of Singapore

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Yi-Chin Toh

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Department of Biomedical Engineering,Singapore Institute of Neurotechnology (SINAPSE)

National University of Singapore

Stencil Micropatterning of Human Pluripotent Stem Cells for Probing Spatial Organization of Differentiation Fates

Department of Biomedical Engineering,
Singapore Institute of Neurotechnology (SINAPSE)