Yi Chen

Department of Physiology and Biophysics, University of Washington

Affiliated withUniversity of Washington Biogen, Inc.Shanghai Jiao Tong University

Research Area

MedicineNeuroscienceBioengineering

Biography

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JoVE Journal Publications

Article Total : 3	Year
Publication title	2016
Publication title	2019
Publication title	2022

Other Publications

Article	Year
A case-control association study between the GRID1 gene and schizophrenia in the Chinese Northern Han population. Schizophrenia research\| PubMed ID: 17490860	2007
Genome-wide survey and developmental expression mapping of zebrafish SET domain-containing genes. PloS one\| PubMed ID: 18231586	2008
eena Promotes myeloid proliferation through stimulating ERK1/2 phosphorylation in zebrafish. The Journal of biological chemistry\| PubMed ID: 18413315	2008
Functional characterization of Lmo2-Cre transgenic zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 18627109	2008
Nr4a2 is essential for the differentiation of dopaminergic neurons during zebrafish embryogenesis. Molecular and cellular neurosciences\| PubMed ID: 18638558	2008
In vivo interstitial migration of primitive macrophages mediated by JNK-matrix metalloproteinase 13 signaling in response to acute injury. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18641354	2008
Mir-144 selectively regulates embryonic alpha-hemoglobin synthesis during primitive erythropoiesis. Blood\| PubMed ID: 18941117	2009
Functional SNPs in the SCGB3A2 promoter are associated with susceptibility to Graves' disease. Human molecular genetics\| PubMed ID: 19126779	2009
Experimental validation and complexity of miRNA-mRNA target interaction during zebrafish primitive erythropoiesis. Biochemical and biophysical research communications\| PubMed ID: 19254693	2009
Heritable and lineage-specific gene knockdown in zebrafish embryo. PloS one\| PubMed ID: 19582161	2009
Isolation and characterization of a GS2 gene in melon (Cucumis melo L.) and its expression patterns under the fertilization of different forms of N. Molecular biotechnology\| PubMed ID: 19669951	2010
Setdb2 restricts dorsal organizer territory and regulates left-right asymmetry through suppressing fgf8 activity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20133783	2010
pH-sensitive supramolecular polypeptide-based micelles and reverse micelles mediated by hydrogen-bonding interactions or host-guest chemistry: characterization and in vitro controlled drug r... The journal of physical chemistry. B\| PubMed ID: 20469900	2010
Distribution and clinical features of primary immunodeficiency diseases in Chinese children (2004-2009). Journal of clinical immunology\| PubMed ID: 21243521	2011
Dominant-negative C/ebpα and polycomb group protein Bmi1 extend short-lived hematopoietic stem/progenitor cell life span and induce lethal dyserythropoiesis. Blood\| PubMed ID: 21828130	2011
Stimuli-responsive polypeptide-based reverse micellar hydrogel. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 22195800	2011
Short reaction of C-peptide, glucagon-like peptide-1, ghrelin and endomorphin-1 for different style diet in type 2 diabetic patients. Chinese medical journal\| PubMed ID: 22340163	2011
Phospholipase C gamma-1 is required for granulocyte maturation in zebrafish. Developmental biology\| PubMed ID: 23220656	2013
Plasma Endothelial Microparticles, TNF-a and IL-6 in Kawasaki Disease. Indian pediatrics\| PubMed ID: 23255681	2013
Association of genetic polymorphisms with chronic obstructive pulmonary disease in the Chinese Han population: a case-control study. BMC medical genomics\| PubMed ID: 23267696	2012
Cannabinoid receptor 2 suppresses leukocyte inflammatory migration by modulating the JNK/c-Jun/Alox5 pathway. The Journal of biological chemistry\| PubMed ID: 23539630	2013
Activated N-Ras signaling regulates arterial-venous specification in zebrafish. Journal of hematology & oncology\| PubMed ID: 23663822	2013
miR-34b regulates multiciliogenesis during organ formation in zebrafish. Development (Cambridge, England)\| PubMed ID: 23698347	2013
GSK-3/CREB pathway involved in the gx-50's effect on Alzheimer's disease. Neuropharmacology\| PubMed ID: 24565641	2014
Setdb2 controls convergence and extension movements during zebrafish gastrulation by transcriptional regulation of dvr1. Developmental biology\| PubMed ID: 24892953	2014
Effect of CTRP3 on activation of adventitial fibroblasts induced by TGF-β1 from rat aorta in vitro. International journal of clinical and experimental pathology\| PubMed ID: 24966928	2014
miR-142-3p acts as an essential modulator of neutrophil development in zebrafish. Blood\| PubMed ID: 24990885	2014
A stationary computed tomography system with cylindrically distributed sources and detectors. Journal of X-ray science and technology\| PubMed ID: 25408388	2014
DNaseI protects against Paraquat-induced acute lung injury and pulmonary fibrosis mediated by mitochondrial DNA. BioMed research international\| PubMed ID: 25759818	2015
Vibsanin B preferentially targets HSP90β, inhibits interstitial leukocyte migration, and ameliorates experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25810397	2015
Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients. The Cochrane database of systematic reviews\| PubMed ID: 25879090	2015
DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish. Journal of hematology & oncology\| PubMed ID: 25886310	2015
Anti-Endothelin Receptor Type A Autoantibodies in Systemic Lupus Erythematosus-Associated Pulmonary Arterial Hypertension. Arthritis & rheumatology (Hoboken, N.J.)\| PubMed ID: 26018988	2015
TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis. PLoS genetics\| PubMed ID: 26131719	2015
Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction. Cell research\| PubMed ID: 26138676	2015
Vitamin D is associated with testosterone and hypogonadism in Chinese men: Results from a cross-sectional SPECT-China study. Reproductive biology and endocrinology : RB&E\| PubMed ID: 26177638	2015
Gx-50 reduces β-amyloid-induced TNF-α, IL-1β, NO, and PGE2 expression and inhibits NF-κB signaling in a mouse model of Alzheimer's disease. European journal of immunology\| PubMed ID: 26643273	2016
Causes, clinical features and outcomes of drug-induced liver injury in hospitalized patients in a Chinese tertiary care hospital. SpringerPlus\| PubMed ID: 26702391	2015
Ectopic expression of Hoxb4a in hemangioblasts promotes hematopoietic development in early embryogenesis of zebrafish. Clinical and experimental pharmacology & physiology\| PubMed ID: 26743678	2015
Visceral fat dysfunction is positively associated with hypogonadism in Chinese men. Scientific reports\| PubMed ID: 26796865	2016
Low vitamin D levels and non-alcoholic fatty liver disease, evidence for their independent association in men in East China: a cross-sectional study (Survey on Prevalence in East China for M... The British journal of nutrition\| PubMed ID: 26888280	2016
Heat shock protein A12B protects against sepsis-induced impairment in vascular endothelial permeability. The Journal of surgical research\| PubMed ID: 27083952	2016
Blood cadmium in Chinese adults and its relationships with diabetes and obesity. Environmental science and pollution research international\| PubMed ID: 27312901	2016
Optimization-based scatter estimation using primary modulation for computed tomography. Medical physics\| PubMed ID: 27487893	2016
Blockade of CXC chemokine receptor 3 on endothelial cells protects against sepsis-induced acute lung injury. The Journal of surgical research\| PubMed ID: 27565063	2016
Osteosarcoma of the Mandible: A Site-Specific Study on Survival and Prognostic Factors. The Journal of craniofacial surgery\| PubMed ID: 28005728	2016
Draft Genome Sequences of Three Isolates from Foods in China. Genome announcements\| PubMed ID: 28428307	2017
The differential spatiotemporal expression pattern of shelterin genes throughout lifespan. Aging\| PubMed ID: 28437249	2017
Is Transforming Growth Factor β1 a Cause of Hypertension? American journal of hypertension\| PubMed ID: 28575145	2017
Utility of Fluorescence In Situ Hybridization (FISH) to Sub-Classify Low-Grade Urothelial Carcinoma for Prognostication. Medical science monitor : international medical journal of experimental and clinical research\| PubMed ID: 28655867	2017
JAM-A overexpression is related to disease progression in diffuse large B-cell lymphoma and downregulated by lenalidomide. Scientific reports\| PubMed ID: 28785100	2017
Association of lead exposure with cardiovascular risk factors and diseases in Chinese adults. Environmental science and pollution research international\| PubMed ID: 28799038	2017
Follicle-Stimulating Hormone, Its Association with Cardiometabolic Risk Factors, and 10-Year Risk of Cardiovascular Disease in Postmenopausal Women. Journal of the American Heart Association\| PubMed ID: 28855169	2017
Atrial fibrillation screening during automated blood pressure measurement-Comment on "Diagnostic accuracy of new algorithm to detect atrial fibrillation in a home blood pressure monitor". Journal of clinical hypertension (Greenwich, Conn.)\| PubMed ID: 28942614	2017
Visceral adiposity and renal function: an observational study from SPECT-China. Lipids in health and disease\| PubMed ID: 29078775	2017
Iodized Salt Intake and Its Association with Urinary Iodine, Thyroid Peroxidase Antibodies, and Thyroglobulin Antibodies Among Urban Chinese. Thyroid : official journal of the American Thyroid Association\| PubMed ID: 29092685	2017
Stability and recovery of DNA origami structure with cation concentration. Nanotechnology\| PubMed ID: 29182155	2018
The histone demethylase Jmjd3 regulates zebrafish myeloid development by promoting spi1 expression. Biochimica et biophysica acta\| PubMed ID: 29378332	2018
Clinical usefulness of noninvasively estimated central blood pressure. Journal of hypertension\| PubMed ID: 29697478	2018
The Association of Thyroid Nodules with Metabolic Status: A Cross-Sectional SPECT-China Study. International journal of endocrinology\| PubMed ID: 29721016	2018
Phytoplankton response to polystyrene microplastics: Perspective from an entire growth period. Chemosphere\| PubMed ID: 29860145	2018
The association of non-alcoholic fatty liver disease with thyroid peroxidase and thyroglobulin antibody: A new insight from SPECT-China study. Autoimmunity\| PubMed ID: 30016121	2018
Comparison of Acceptable Noise Level Generated Using Different Transducers and Response Modes. Neural plasticity\| PubMed ID: 30046301	2018
Foxp2 regulates anatomical features that may be relevant for vocal behaviors and bipedal locomotion. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 30104377	2018
Evaluation of the dental spectral cone beam CT for metal artefact reduction. Dento maxillo facial radiology\| PubMed ID: 30299983	2019
DNA Methylation Inhibitor 5-Aza-2'-Deoxycytidine Modulates Endometrial Receptivity Through Upregulating HOXA10 Expression. Reproductive sciences (Thousand Oaks, Calif.)\| PubMed ID: 30522400	2019
Detection of pulmonary ground-glass opacity based on deep learning computer artificial intelligence. Biomedical engineering online\| PubMed ID: 30670024	2019
Quantitative mapping of DNA phosphorothioatome reveals phosphorothioate heterogeneity of low modification frequency. PLoS genetics\| PubMed ID: 30933976	2019
Comparison of Abdominal Obesity and Fatty Liver and Their Association with Insulin Resistance and Metabolic Syndrome in Chinese Adults. Obesity (Silver Spring, Md.)\| PubMed ID: 30942551	2019
Cross-sectional Association Between Blood Pressure Status and Atrial Fibrillation in an Elderly Chinese Population. American journal of hypertension\| PubMed ID: 31004151	2019
A new radiation force balance method for measuring diverging piston source power in the frequency range 20-100 kHz: Theory and experimental verification. Ultrasonics\| PubMed ID: 31005764	2019
Network pharmacology-based identification for therapeutic mechanism of Ling-Gui-Zhu-Gan decoction in the metabolic syndrome induced by antipsychotic drugs. Computers in biology and medicine\| PubMed ID: 31085379	2019
Novel Iodine-induced Cleavage Real-time PCR Assay for Accurate Quantification of Phosphorothioate Modified Sites in Bacterial DNA. Scientific reports\| PubMed ID: 31097783	2019
Assessing consistent condom use among migrant men who have sex with men in Shanghai, China: validation of an information-motivation-behavioural skills model. BMC infectious diseases\| PubMed ID: 31122201	2019
Follicle-stimulating hormone promotes renal tubulointerstitial fibrosis in aging women via the AKT/GSK-3β/β-catenin pathway. Aging cell\| PubMed ID: 31243899	2019
TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling. Nature communications\| PubMed ID: 31253779	2019
C-peptide is associated with NAFLD inflammatory and fibrotic progression in type 2 diabetes. Diabetes/metabolism research and reviews\| PubMed ID: 31351021	2020
Novel associations between sex hormones and diabetic vascular complications in men and postmenopausal women: a cross-sectional study. Cardiovascular diabetology\| PubMed ID: 31366359	2019
MicroRNA-29a Involvement in Phenotypic Transformation of Venous Smooth Muscle Cells Via Ten-Eleven Translocation Methylcytosinedioxygenase 1 in Response to Mechanical Cyclic Stretch. Journal of biomechanical engineering\| PubMed ID: 31513704	2020
Mortality risk prediction in lupus patients complicated with invasive infection in the emergency department: LUPHAS score. Therapeutic advances in musculoskeletal disease\| PubMed ID: 31723357	2019
π-Extended -Symmetric Double NBN-Heterohelicenes with Exceptional Luminescent Properties. Organic letters\| PubMed ID: 31860317	2020
Different associations between serum urate and diabetic complications in men and postmenopausal women. Diabetes research and clinical practice\| PubMed ID: 31911248	2020
Circular RNA circTET3 mediates migration of rat vascular smooth muscle cells by targeting miR-351-5p. Journal of cellular physiology\| PubMed ID: 31990052	2020
Inhibition of Histone Deacetylation by MS-275 Alleviates Colitis by Activating the Vitamin D Receptor. Journal of Crohn's & colitis\| PubMed ID: 32030401	2020
Deficiency in the anti-apoptotic protein DJ-1 promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel disease via p53. The Journal of biological chemistry\| PubMed ID: 32075910	2020
The Associations Between Gonadal Hormones and Serum Uric Acid Levels in Men and Postmenopausal Women With Diabetes. Frontiers in endocrinology\| PubMed ID: 32153501	2020
SENP3 in monocytes/macrophages up-regulates tissue factor and mediates lipopolysaccharide-induced acute lung injury by enhancing JNK phosphorylation. Journal of cellular and molecular medicine\| PubMed ID: 32237051	2020
Theranostics system caged in human serum albumin as a therapy for breast tumors. Journal of materials chemistry. B\| PubMed ID: 32249887	2020
Predictive value of circulating plasma mitochondrial DNA for Sepsis in the emergency department: observational study based on the Sepsis-3 definition. BMC emergency medicine\| PubMed ID: 32299369	2020
Thyroid Parameters and Kidney Disorder in Type 2 Diabetes: Results from the METAL Study. Journal of diabetes research\| PubMed ID: 32337292	2020
Associations between the Neutrophil-to-Lymphocyte Ratio and Diabetic Complications in Adults with Diabetes: A Cross-Sectional Study. Journal of diabetes research\| PubMed ID: 32405503	2020
A new approach to prevent cervical stenosis in postmenopausal women after loop electrosurgical excision procedure: a randomized controlled trial. Scientific reports\| PubMed ID: 32444670	2020
The unique association between the level of peripheral blood monocytes and the prevalence of diabetic retinopathy: a cross-sectional study. Journal of translational medicine\| PubMed ID: 32571335	2020
Value of endocervical curettage in follow-up for patients with cervical intraepithelial neoplasia stage 2+ after loop electrosurgical excision. Gynecologic oncology\| PubMed ID: 32586604	2020
Cardiac Na-Ca exchanger 1 (ncx1h) is critical for the ventricular cardiomyocyte formation via regulating the expression levels of gata4 and hand2 in zebrafish. Science China. Life sciences\| PubMed ID: 32648190	2021
Detection rate and treatment gap for atrial fibrillation identified through screening in community health centers in China (AF-CATCH): A prospective multicenter study. PLoS medicine\| PubMed ID: 32673305	2020
Associations between different bilirubin subtypes and diabetic microvascular complications in middle-aged and elderly individuals. Therapeutic advances in endocrinology and metabolism\| PubMed ID: 32699586	2020
Associations between abdominal obesity indices and diabetic complications: Chinese visceral adiposity index and neck circumference. Cardiovascular diabetology\| PubMed ID: 32736628	2020
knockout zebrafish is viable and fertile: differential and developmental stress-related requirements for Setd2 and histone H3K36 trimethylation in different vertebrate animals. Cell discovery\| PubMed ID: 33088589	2020
Corrigendum to: Inhibition of Histone Deacetylation by MS-275 Alleviates Colitis by Activating the Vitamin D Receptor. Journal of Crohn's & colitis\| PubMed ID: 33125476	2021
Utility of basophil activation test for predicting the outcome of wheezing in children: a pilot study. BMC immunology\| PubMed ID: 33407109	2021
Platelet-derived microvesicles induce calcium oscillations and promote VSMC migration TRPV4. Theranostics\| PubMed ID: 33500733	2021
LncRNA NKX2-1-AS1 promotes tumor progression and angiogenesis via upregulation of SERPINE1 expression and activation of the VEGFR-2 signaling pathway in gastric cancer. Molecular oncology\| PubMed ID: 33512745	2021
Universal LNA Probe-Mediated Multiplex Droplet Digital Polymerase Chain Reaction for Ultrasensitive and Accurate Quantitative Analysis of Genetically Modified Organisms. Journal of agricultural and food chemistry\| PubMed ID: 33528262	2021
Blood lead, vitamin D status, and albuminuria in patients with type 2 diabetes. Environmental pollution (Barking, Essex : 1987)\| PubMed ID: 33607353	2021
Platelet-Derived Extracellular Vesicles Increase Col8a1 Secretion and Vascular Stiffness in Intimal Injury. Frontiers in cell and developmental biology\| PubMed ID: 33738288	2021
Circular RNA UVRAG Mediated by Alternative Splicing Factor NOVA1 Regulates Adhesion and Migration of Vascular Smooth Muscle Cells. Genes\| PubMed ID: 33799408	2021
Urinary Biomarkers of Phthalates Exposure, Blood Lead Levels, and Risks of Thyroid Nodules. Toxics\| PubMed ID: 33810189	2021
Effectively Intervening Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells With a Combination of ROCK and TGF-β Signaling Inhibitors. Investigative ophthalmology & visual science\| PubMed ID: 33861322	2021
Early-life exposure to the Chinese famine, genetic susceptibility and the risk of type 2 diabetes in adulthood. Diabetologia\| PubMed ID: 33885932	2021
Association of blood culture with carbapenem use in pyogenic liver abscess: a two-center retrospective study. BMC emergency medicine\| PubMed ID: 33941097	2021
A pilot study to evaluate the role of circulation CD4 CCR6 CRTh2 cell in predicting risk of asthma in wheezing children. BMC pediatrics\| PubMed ID: 34090369	2021
Tanshinone I, a new EZH2 inhibitor restricts normal and malignant hematopoiesis through upregulation of and . Theranostics\| PubMed ID: 34093860	2021
Influence of Rapid Urbanization on Thyroid Autoimmune Disease in China. International journal of endocrinology\| PubMed ID: 34122544	2021
Extracellular matrix stiffness controls VEGF secretion and neuroblastoma angiogenesis via the YAP/RUNX2/SRSF1 axis. Angiogenesis\| PubMed ID: 34170441	2022
3,3',5-Triiodothyroacetic acid (TRIAC) induces embryonic ζ-globin expression via thyroid hormone receptor α. Journal of hematology & oncology\| PubMed ID: 34174920	2021
Gene-gene and gene-environment interactions on cord blood total IgE in Chinese Han children. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology\| PubMed ID: 34243801	2021
International Classification of Retinopathy of Prematurity, Third Edition. Ophthalmology\| PubMed ID: 34247850	2021
Combining C reactive protein and serum albumin to predict 90-day mortality in systemic lupus erythematosus with serious community-acquired infections. Lupus science & medicine\| PubMed ID: 34253648	2021
Glucagon is associated with NAFLD inflammatory progression in type 2 diabetes, not with NAFLD fibrotic progression. European journal of gastroenterology & hepatology\| PubMed ID: 34402473	2021
Intervention Effect of Rapid Rehabilitation Nursing Combined with Continuous Nursing after Discharge on Patients with Cerebral Infarction in Recovery Period and the Changes in Motor Function... Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 34691226	2021
Selective and competitive functions of the AAR and UPR pathways in stress-induced angiogenesis. Cell discovery\| PubMed ID: 34697290	2021
Tpr Deficiency Disrupts Erythroid Maturation With Impaired Chromatin Condensation in Zebrafish Embryogenesis. Frontiers in cell and developmental biology\| PubMed ID: 34722501	2021
A GIS-Based Approach for Flood Risk Zoning by Combining Social Vulnerability and Flood Susceptibility: A Case Study of Nanjing, China. International journal of environmental research and public health\| PubMed ID: 34770118	2021
Performance of Procalcitonin to Distinguish Fungal from Bacterial Infections in Patients with Systemic Lupus Erythematosus. Infection and drug resistance\| PubMed ID: 34815675	2021
Impact of Platelet Transfusion Thresholds on Outcomes of Patients With Sepsis: Analysis of the MIMIC-IV Database. Shock (Augusta, Ga.)\| PubMed ID: 34966069	2022
Different Stability of DNA Origami Nanostructure between on Interface and in Bulk Solution. ACS applied bio materials\| PubMed ID: 34996247	2018
Basiliximab for steroid-refractory acute graft-versus-host disease: A real-world analysis. American journal of hematology\| PubMed ID: 35064928	2022
Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD. Cell discovery\| PubMed ID: 35169121	2022
Association between sex hormone-binding globulin and kidney function in men: results from the SPECT-China study. Chinese medical journal\| PubMed ID: 35170516	2022
Loss of in Zebrafish as a Model of Ataxia-Telangiectasia Syndrome. Biomedicines\| PubMed ID: 35203601	2022
Alcohol consumption in relation to the incidence of atrial fibrillation in an elderly Chinese population. Journal of geriatric cardiology : JGC\| PubMed ID: 35233223	2022
Platelet Transfusion in Patients With Sepsis and Thrombocytopenia: A Propensity Score-Matched Analysis Using a Large ICU Database. Frontiers in medicine\| PubMed ID: 35252261	2022
Correlation between vaginal microbiota and different progression stages of cervical cancer. Genetics and molecular biology\| PubMed ID: 35320337	2022