Alexander Yu. Nikitin

Cell lineage-specific effects associated with multiple deficiencies of tumor susceptibility genes in Msh2(-/-)Rb(+/-) mice.

ARF mutation accelerates pituitary tumor development in Rb+/- mice.

Minimal effects of dietary restriction on neuroendocrine carcinogenesis in Rb+/- mice.

Female mice chimeric for expression of the simian virus 40 TAg under control of the MISIIR promoter develop epithelial ovarian cancer.

Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation.

Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium.

Mammary carcinoma suppression by cellular retinoic acid binding protein-II.

Classification of proliferative pulmonary lesions of the mouse: recommendations of the mouse models of human cancers consortium.

Somatic mutation of p53 leads to estrogen receptor alpha-positive and -negative mouse mammary tumors with high frequency of metastasis.

Use of multiphoton imaging for studying cell migration in the mouse.

Suppression of melanotroph carcinogenesis leads to accelerated progression of pituitary anterior lobe tumors and medullary thyroid carcinomas in Rb+/- mice.

Cyclooxygenase-1 is overexpressed in multiple genetically engineered mouse models of epithelial ovarian cancer.

Synergy of p53 and Rb deficiency in a conditional mouse model for metastatic prostate cancer.

Precancer in mice: animal models used to understand, prevent, and treat human precancers.

Training mouse pathologists: five years of pathology of mouse models of human disease workshops.

Prostate cancer associated with p53 and Rb deficiency arises from the stem/progenitor cell-enriched proximal region of prostatic ducts.

From whence will they come? - A perspective on the acute shortage of pathologists in biomedical research.

Mouse models of prostate adenocarcinoma with the capacity to monitor spontaneous carcinogenesis by bioluminescence or fluorescence.

MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth.

Cell lineage-specific interactions between Men1 and Rb in neuroendocrine neoplasia.

Toxicity and biomedical imaging of layered nanohybrids in the mouse.

Broad overexpression of ribonucleotide reductase genes in mice specifically induces lung neoplasms.

Disruption of the circadian clock due to the Clock mutation has discrete effects on aging and carcinogenesis.

Pro-neural transcription factors as cancer markers.

Overcoming retinoic acid-resistance of mammary carcinomas by diverting retinoic acid from PPARbeta/delta to RAR.

Role of p53 and Rb in ovarian cancer.

MicroRNA and ovarian cancer.

Do-it-yourself (DIY) pathology.

Mouse models for cancer stem cell research.

EGF potentiated oncogenesis requires a tissue transglutaminase-dependent signaling pathway leading to Src activation.

Frequent downregulation of miR-34 family in human ovarian cancers.

Strategies for high-resolution imaging of epithelial ovarian cancer by laparoscopic nonlinear microscopy.

Mouse prostate cancer cell lines established from primary and postcastration recurrent tumors.

Local mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiency.

Advancing translational research.

Dominant activation of the hedgehog signaling pathway alters development of the female reproductive tract.

Wild-type p53 controls cell motility and invasion by dual regulation of MET expression.

MET-dependent cancer invasion may be preprogrammed by early alterations of p53-regulated feedforward loop and triggered by stromal cell-derived HGF.

Training mouse pathologists: ten years of workshops on the Pathology of Mouse Models of Human Disease.

Challenges in pre-clinical testing of anti-cancer drugs in cell culture and in animal models.

Implanted adipose progenitor cells as physicochemical regulators of breast cancer.

c-kit+ precursors support postinfarction myogenesis in the neonatal, but not adult, heart.

Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche.

Effects of Jianpi Jiedu Recipe on reversion of P-glycoprotein-mediated multidrug resistance through COX-2 pathway in colorectal cancer.

Detection and organ-specific ablation of neuroendocrine cells by synaptophysin locus-based BAC cassette in transgenic mice.

Loss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinoma.

PTEN is a potent suppressor of small cell lung cancer.

miR-34 cooperates with p53 in suppression of prostate cancer by joint regulation of stem cell compartment.

The Thoc1 ribonucleoprotein and prostate cancer progression.

A Quest for Better Mouse Models of Breast and Ovarian Cancers.

Role of the stem cell niche in the pathogenesis of epithelial ovarian cancers.