Maja Cemazar

Department of Experimental Oncology, Institute of Oncology Ljubljana

Affiliated withInstitute of Oncology Ljubljana University of Primorska University of Primorska

Research Area

Cancer Research

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2016

Other Publications

Article	Year
Effective gene transfer to solid tumors using different nonviral gene delivery techniques: electroporation, liposomes, and integrin-targeted vector. Cancer gene therapy\| PubMed ID: 11960291	2002
Schedule-dependent interaction between vinblastine and cisplatin in Ehrlich ascites tumors in mice. The Journal of pharmacology and experimental therapeutics\| PubMed ID: 12065735	2002
Perturbation of blood flow as a mechanism of anti-tumour action of direct current electrotherapy. Physiological measurement\| PubMed ID: 12636188	2003
Electroporation of LPB sarcoma cells in vitro and tumors in vivo increases the radiosensitizing effect of cisplatin. Anticancer research\| PubMed ID: 12680224	2003
Pt(II) complexes with N-(3-pyridyl)-2-(4-(trifluoromethyl)phenyl)diazenecarboxamide and their reactions with glutathione. Journal of inorganic biochemistry\| PubMed ID: 12763654	2003
Effects of electrogenetherapy with p53wt combined with cisplatin on curvival of human tumor cell lines with different p53 status. DNA and cell biology\| PubMed ID: 14683587	2003
EPR oximetry of tumors in vivo in cancer therapy. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy\| PubMed ID: 15134738	2004
Electrochemotherapy with cisplatin of cutaneous tumor lesions in breast cancer. Anti-cancer drugs\| PubMed ID: 15205602	2004
Antitumour effectiveness of hyperthermia is potentiated by local application of electric pulses to LPB tumours in mice. Anticancer research\| PubMed ID: 15330182	2004
Direct visualization of electroporation-assisted in vivo gene delivery to tumors using intravital microscopy - spatial and time dependent distribution. BMC cancer\| PubMed ID: 15546484	2004
Successful sphincter-saving treatment of anorectal malignant melanoma with electrochemotherapy, local excision and adjuvant brachytherapy. Anti-cancer drugs\| PubMed ID: 15711188	2005
The effect of high frequency electric pulses on muscle contractions and antitumor efficiency in vivo for a potential use in clinical electrochemotherapy. Bioelectrochemistry (Amsterdam, Netherlands)\| PubMed ID: 15713562	2005
Effective treatment of perianal tumors in dogs with electrochemotherapy. Anticancer research\| PubMed ID: 15868917	2005
Crystal structures and cytotoxicity of isopropylamine Pt(II) complexes: a trinuclear squarato-bridged [Pt3(mu2-C4O4)3(H2NPri)6].3H2O and a mononuclear cis-[Pt(NO3)2(H2NPri)2]. Journal of inorganic biochemistry\| PubMed ID: 15927264	2005
Radiosensitising effect of electrochemotherapy with bleomycin in LPB sarcoma cells and tumors in mice. BMC cancer\| PubMed ID: 16168056	2005
Sequence and time dependence of transfection efficiency of electrically-assisted gene delivery to tumors in mice. Current drug delivery\| PubMed ID: 16472096	2006
Cytotoxicity of different platinum (II) analogues to human tumour cell lines in vitro and murine tumour in vivo alone or combined with electroporation. Anticancer research\| PubMed ID: 16827135	2006
In vivo imaging of tumor growth after electrochemotherapy with cisplatin. Biochemical and biophysical research communications\| PubMed ID: 16899227	2006
The endothelial cytoskeleton as a target of electroporation-based therapies. Molecular cancer therapeutics\| PubMed ID: 17172418	2006
Electrogene therapy with p53 of murine sarcomas alone or combined with electrochemotherapy using cisplatin. DNA and cell biology\| PubMed ID: 17233116	2006
Effective treatment of multiple unresectable skin melanoma metastases by electrochemotherapy. Croatian medical journal\| PubMed ID: 17589984	2007
Electrotransfer of therapeutic molecules into tissues. Current opinion in molecular therapeutics\| PubMed ID: 18041666	2007
Gene electrotransfer into murine skeletal muscle: a systematic analysis of parameters for long-term gene expression. Technology in cancer research & treatment\| PubMed ID: 18345697	2008
The effect of electroporation pulses on functioning of the heart. Medical & biological engineering & computing\| PubMed ID: 18415132	2008
Electrochemotherapy compared to surgery for treatment of canine mast cell tumours. In vivo (Athens, Greece)\| PubMed ID: 19368125	2009
Limb sparing treatment of bleeding melanoma recurrence by electrochemotherapy. Tumori\| PubMed ID: 19688986	2009
Electric pulses used in electrochemotherapy and electrogene therapy do not significantly change the expression profile of genes involved in the development of cancer in malignant melanoma ce... BMC cancer\| PubMed ID: 19709437	2009
Local and systemic antitumor effect of intratumoral and peritumoral IL-12 electrogene therapy on murine sarcoma. Cancer biology & therapy\| PubMed ID: 19755854	2009
Controlled systemic release of interleukin-12 after gene electrotransfer to muscle for cancer gene therapy alone or in combination with ionizing radiation in murine sarcomas. The journal of gene medicine\| PubMed ID: 19777440	2009
Melanoma metastases to the neck nodes: role of adjuvant irradiation. International journal of radiation oncology, biology, physics\| PubMed ID: 19910139	2010
Radiosensitizing effect of electrochemotherapy in a fractionated radiation regimen in radiosensitive murine sarcoma and radioresistant adenocarcinoma tumor model. Radiation research\| PubMed ID: 19929414	2009
Towards treatment planning and treatment of deep-seated solid tumors by electrochemotherapy. Biomedical engineering online\| PubMed ID: 20178589	2010
Metastatic potential of melanoma cells is not affected by electrochemotherapy. Melanoma research\| PubMed ID: 20216102	2011
Irradiation, cisplatin, and 5-azacytidine upregulate cytomegalovirus promoter in tumors and muscles: implementation of non-invasive fluorescence imaging. Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging\| PubMed ID: 20396957	2011
Antivascular effects of electrochemotherapy: implications in treatment of bleeding metastases. Expert review of anticancer therapy\| PubMed ID: 20470005	2010
Cancer electrogene therapy with interleukin-12. Current gene therapy\| PubMed ID: 20560875	2010
Increased cellular uptake of biocompatible superparamagnetic iron oxide nanoparticles into malignant cells by an external magnetic field. The Journal of membrane biology\| PubMed ID: 20602230	2010
The influence of electroporation on cytotoxicity of anticancer ruthenium(III) complex KP1339 in vitro and in vivo. Anticancer research\| PubMed ID: 20651351	2010
Hyaluronidase and collagenase increase the transfection efficiency of gene electrotransfer in various murine tumors. Human gene therapy\| PubMed ID: 21797718	2012
Electrochemotherapy of chest wall breast cancer recurrence. Cancer treatment reviews\| PubMed ID: 21856080	2011
Surface modified magnetic nanoparticles for immuno-gene therapy of murine mammary adenocarcinoma. Biomaterials\| PubMed ID: 22429983	2012
In vivo molecular imaging and histological analysis of changes induced by electric pulses used for plasmid DNA electrotransfer to the skin: a study in a dorsal window chamber in mice. The Journal of membrane biology\| PubMed ID: 22644389	2012
Development of human cell biosensor system for genotoxicity detection based on DNA damage-induced gene expression. Radiology and oncology\| PubMed ID: 22933890	2010
Electrogene therapy with interleukin-12 in canine mast cell tumors. Radiology and oncology\| PubMed ID: 22933932	2011
Assessment of the tumourigenic and metastatic properties of SK-MEL28 melanoma cells surviving electrochemotherapy with bleomycin. Radiology and oncology\| PubMed ID: 22933978	2012
Intravital microscopy at the single vessel level brings new insights of vascular modification mechanisms induced by electropermeabilization. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 23017380	2012
IL-12 based gene therapy in veterinary medicine. Journal of translational medicine\| PubMed ID: 23171444	2012
Differential cellular effects of electroporation and electrochemotherapy in monolayers of human microvascular endothelial cells. PloS one\| PubMed ID: 23300747	2012
Is survivin expression prognostic or predictive in malignant pleural mesothelioma? Virchows Archiv : an international journal of pathology\| PubMed ID: 23358691	2013
Radiosensitizing effect of intratumoral interleukin-12 gene electrotransfer in murine sarcoma. BMC cancer\| PubMed ID: 23360213	2013
Potentiation of electrochemotherapy by intramuscular IL-12 gene electrotransfer in murine sarcoma and carcinoma with different immunogenicity. Radiology and oncology\| PubMed ID: 23412658	2012
Tumor size and effectiveness of electrochemotherapy. Radiology and oncology\| PubMed ID: 23450195	2013
Differential mechanisms associated with vascular disrupting action of electrochemotherapy: intravital microscopy on the level of single normal and tumor blood vessels. PloS one\| PubMed ID: 23555705	2013
Multiple delivery of siRNA against endoglin into murine mammary adenocarcinoma prevents angiogenesis and delays tumor growth. PloS one\| PubMed ID: 23593103	2013
Biological properties of melanoma and endothelial cells after plasmid AMEP gene electrotransfer depend on integrin quantity on cells. The Journal of membrane biology\| PubMed ID: 23649038	2013
In vitro targeted gene electrotransfer to endothelial cells with plasmid DNA containing human endothelin-1 promoter. The Journal of membrane biology\| PubMed ID: 23652810	2013
Magnetofection: a reproducible method for gene delivery to melanoma cells. BioMed research international\| PubMed ID: 23862136	2013
Gene electrotransfer of plasmid antiangiogenic metargidin peptide (AMEP) in disseminated melanoma: safety and efficacy results of a phase I first-in-man study. Human gene therapy. Clinical development\| PubMed ID: 23980876	2013
In vivo real-time monitoring system of electroporation mediated control of transdermal and topical drug delivery. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 24113487	2013
Electrochemotherapy with intravenous bleomycin injection: an observational study in superficial squamous cell carcinoma in cats. Journal of feline medicine and surgery\| PubMed ID: 24127456	2014
A novel method for speciation of Pt in human serum incubated with cisplatin, oxaliplatin and carboplatin by conjoint liquid chromatography on monolithic disks with UV and ICP-MS detection. Talanta\| PubMed ID: 24148385	2013
Determination of vinblastine in tumour tissue with liquid chromatography-high resolution mass spectrometry. Talanta\| PubMed ID: 24148490	2013
Evaluation of p21 promoter for interleukin 12 radiation induced transcriptional targeting in a mouse tumor model. Molecular cancer\| PubMed ID: 24219565	2013
Effect of ionizing radiation on human skeletal muscle precursor cells. Radiology and oncology\| PubMed ID: 24294183	2013
Changing electrode orientation, but not pulse polarity, increases the efficacy of gene electrotransfer to tumors in vivo. Bioelectrochemistry (Amsterdam, Netherlands)\| PubMed ID: 24411306	2014
Low-magnification image analysis of Giemsa stained, electroporation and bleomycin treated endothelial monolayers provides reliable monolayer integrity data. Toxicology in vitro : an international journal published in association with BIBRA\| PubMed ID: 24412537	2014
Schedule-dependent interaction between vinblastine and irradiation in experimental sarcoma. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]\| PubMed ID: 24615190	2014
Different incubation times of cells after gene electrotransfer in fetal bovine serum affect cell viability, but not transfection efficiency. The Journal of membrane biology\| PubMed ID: 24648010	2014
Intraoperative electrochemotherapy of colorectal liver metastases. Journal of surgical oncology\| PubMed ID: 24782355	2014
A cell-based biosensor system HepG2CDKN1A-DsRed for rapid and simple detection of genotoxic agents. Biosensors & bioelectronics\| PubMed ID: 24861570	2014
Modulation of activity of known cytotoxic ruthenium(III) compound (KP418) with hampered transmembrane transport in electrochemotherapy in vitro and in vivo. The Journal of membrane biology\| PubMed ID: 24957014	2014
In situ monitoring of electric field distribution in mouse tumor during electroporation. Radiology\| PubMed ID: 25144647	2015
Inhibitor of endocytosis impairs gene electrotransfer to mouse muscle in vivo. Bioelectrochemistry (Amsterdam, Netherlands)\| PubMed ID: 25200990	2015
Mcam Silencing With RNA Interference Using Magnetofection has Antitumor Effect in Murine Melanoma. Molecular therapy. Nucleic acids\| PubMed ID: 25350580	2014
Endoglin silencing has significant antitumor effect on murine mammary adenocarcinoma mediated by vascular targeted effect. Current gene therapy\| PubMed ID: 25619888	2015
Modeling of microvascular permeability changes after electroporation. PloS one\| PubMed ID: 25793292	2015
Adjuvant TNF-α therapy to electrochemotherapy with intravenous cisplatin in murine sarcoma exerts synergistic antitumor effectiveness. Radiology and oncology\| PubMed ID: 25810699	2015
Improved Specificity of Gene Electrotransfer to Skin Using pDNA Under the Control of Collagen Tissue-Specific Promoter. The Journal of membrane biology\| PubMed ID: 25840832	2015
Gene Electrotransfer of Canine Interleukin 12 into Canine Melanoma Cell Lines. The Journal of membrane biology\| PubMed ID: 25840833	2015
Nitroxoline impairs tumor progression in vitro and in vivo by regulating cathepsin B activity. Oncotarget\| PubMed ID: 25848918	2015
Gene Electrotransfer of Plasmid with Tissue Specific Promoter Encoding shRNA against Endoglin Exerts Antitumor Efficacy against Murine TS/A Tumors by Vascular Targeted Effects. PloS one\| PubMed ID: 25909447	2015
Endoglin (CD105) Silencing Mediated by shRNA Under the Control of Endothelin-1 Promoter for Targeted Gene Therapy of Melanoma. Molecular therapy. Nucleic acids\| PubMed ID: 25942402	2015
Electrochemotherapy of tumors as in situ vaccination boosted by immunogene electrotransfer. Cancer immunology, immunotherapy : CII\| PubMed ID: 26067277	2015
Coupling treatment planning with navigation system: a new technological approach in treatment of head and neck tumors by electrochemotherapy. Biomedical engineering online\| PubMed ID: 26355773	2015
Electrochemotherapy of colorectal liver metastases--an observational study of its effects on the electrocardiogram. Biomedical engineering online\| PubMed ID: 26356120	2015
Electrotransfer of Plasmid DNA Encoding an Anti-Mouse Endoglin (CD105) shRNA to B16 Melanoma Tumors with Low and High Metastatic Potential Results in Pronounced Anti-Tumor Effects. Cancers\| PubMed ID: 26712792	2015
Bleomycin pharmacokinetics of bolus bleomycin dose in elderly cancer patients treated with electrochemotherapy. Cancer chemotherapy and pharmacology\| PubMed ID: 26992379	2016
Magnetic field contributes to the cellular uptake for effective therapy with magnetofection using plasmid DNA encoding against Mcam in B16F10 melanoma in vivo. Nanomedicine (London, England)\| PubMed ID: 27021639	2016
Visualization of Nonspecific Antitumor Effectiveness and Vascular Effects of Gene Electro-Transfer to Tumors. Current gene therapy\| PubMed ID: 27029945	2016
Recommendations for improving the quality of reporting clinical electrochemotherapy studies based on qualitative systematic review. Radiology and oncology\| PubMed ID: 27069444	2016
Effectiveness of electrochemotherapy after IFN-α adjuvant therapy of melanoma patients. Radiology and oncology\| PubMed ID: 27069446	2016
Cytotoxic trans-platinum(II) complex with 3-hydroxymethylpyridine: Synthesis, X-ray structure and biological activity evaluation. Journal of inorganic biochemistry\| PubMed ID: 27189143	2016
European Research on Electrochemotherapy in Head and Neck Cancer (EURECA) project: Results of the treatment of skin cancer. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 27267144	2016
Cytosolic DNA Sensor Upregulation Accompanies DNA Electrotransfer in B16.F10 Melanoma Cells. Molecular therapy. Nucleic acids\| PubMed ID: 27271988	2016
Bystander Effect Induced by Electroporation is Possibly Mediated by Microvesicles and Dependent on Pulse Amplitude, Repetition Frequency and Cell Type. The Journal of membrane biology\| PubMed ID: 27371159	2016
Electrotransfer parameters as a tool for controlled and targeted gene expression in skin. Molecular therapy. Nucleic acids\| PubMed ID: 27574782	2016
Identification and quantification of bleomycin in serum and tumor tissue by liquid chromatography coupled to high resolution mass spectrometry. Talanta\| PubMed ID: 27591601	2016
Electrochemotherapy with bleomycin is effective in BRAF mutated melanoma cells and interacts with BRAF inhibitors. Radiology and oncology\| PubMed ID: 27679543	2016