Yuriy Alexandrov

Photonics Group,
Department of Physics,
Photonics Group, Department of Physics

Imperial College London

BIOGRAPHY

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PUBLICATIONS

Automated screening of neurite outgrowth.

Journal of biomolecular screening Feb, 2003 | Pubmed ID: 12854994

Angiogenesis: an improved in vitro biological system and automated image-based workflow to aid identification and characterization of angiogenesis and angiogenic modulators.

Assay and drug development technologies Oct, 2008 | Pubmed ID: 19035850

Microscopy-based HTS examines the mechanism of stress F-actin fiber disruption by cytochalasin D: orientation texture data collated with quantitative kinetic modeling.

Assay and drug development technologies Aug, 2009 | Pubmed ID: 19689205

FLIM FRET technology for drug discovery: automated multiwell-plate high-content analysis, multiplexed readouts and application in situ.

Chemphyschem : a European journal of chemical physics and physical chemistry Feb, 2011 | Pubmed ID: 21337485

Quantification of cellular autofluorescence of human skin using multiphoton tomography and fluorescence lifetime imaging in two spectral detection channels.

Biomedical optics express Dec, 2011 | Pubmed ID: 22162820

Multiphoton multispectral fluorescence lifetime tomography for the evaluation of basal cell carcinomas.

PloS one , 2012 | Pubmed ID: 22984428

Automated fluorescence lifetime imaging plate reader and its application to Förster resonant energy transfer readout of Gag protein aggregation.

Journal of biophotonics May, 2013 | Pubmed ID: 23184449

Rapid global fitting of large fluorescence lifetime imaging microscopy datasets.

PloS one , 2013 | Pubmed ID: 23940626

Mesoscopic in vivo 3-D tracking of sparse cell populations using angular multiplexed optical projection tomography.

Biomedical optics express Apr, 2015 | Pubmed ID: 25909009

Visualising apoptosis in live zebrafish using fluorescence lifetime imaging with optical projection tomography to map FRET biosensor activity in space and time.

Journal of biophotonics Apr, 2016 | Pubmed ID: 26753623

Quantitative in vivo optical tomography of cancer progression & vasculature development in adult zebrafish.

Oncotarget Jul, 2016 | Pubmed ID: 27259259

Conformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET.

Scientific reports Jan, 2017 | Pubmed ID: 28045057

INSTITUTIONS

Imperial College London

JOVE ARTICLES

Open Source High Content Analysis Utilizing Automated Fluorescence Lifetime Imaging Microscopy

Frederik Görlitz^*,1,

Douglas J. Kelly^*,1,

Sean C. Warren¹,

Dominic Alibhai²,

Lucien West³,

Sunil Kumar¹,

Yuriy Alexandrov¹,

Ian Munro¹,

Edwin Garcia¹,

James McGinty¹,

Clifford Talbot¹,

Remigiusz A. Serwa⁴,

Emmanuelle Thinon⁴,

Vincenzo da Paola³,

Edward J. Murray⁵,

Frank Stuhmeier⁶,

Mark A. A. Neil¹,

Edward W. Tate⁴,

Christopher Dunsby^1,7,

Paul M. W. French¹

¹Photonics Group, Department of Physics, Imperial College London,

²Institute for Chemical Biology, Department of Chemistry, Imperial College London,

³MRC Clinical Sciences Centre, Hammersmith Hospital,

⁴Chemical Biology Section, Department of Chemistry, Imperial College London,

⁵, Retroscreen Virology Ltd,

⁶Pfizer Global Research and Development, Pfizer Limited, Sandwich, Kent, UK,

⁷Centre for Histopathology, Imperial College London

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Yuriy Alexandrov

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Imperial College London

Open Source High Content Analysis Utilizing Automated Fluorescence Lifetime Imaging Microscopy

Photonics Group,
Department of Physics,
Photonics Group, Department of Physics