J. Kim Dale

A Hes1-based oscillator in cultured cells and its potential implications for the segmentation clock.

Synchronised cycling gene oscillations in presomitic mesoderm cells require cell-cell contact.

Development on time.

Interfering with Wnt signalling alters the periodicity of the segmentation clock.

Sprouty4, an FGF inhibitor, displays cyclic gene expression under the control of the notch segmentation clock in the mouse PSM.

Notch is a critical component of the mouse somitogenesis oscillator and is essential for the formation of the somites.

Cyclic Nrarp mRNA expression is regulated by the somitic oscillator but Nrarp protein levels do not oscillate.

Notch signalling regulates the contribution of progenitor cells from the chick Hensen's node to the floor plate and notochord.

The segmentation clock mechanism moves up a notch.

BHLH proteins and their role in somitogenesis.

A spatio-temporal model of Notch signalling in the zebrafish segmentation clock: conditions for synchronised oscillatory dynamics.

Somitogenesis.

The prevalence and origin of exoprotease producing cells in the Bacillus subtilis biofilm.

Spatiotemporal oscillations of Notch1, Dll1 and NICD are coordinated across the mouse PSM.

A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo.

A balance of positive and negative regulators determines the pace of the segmentation clock.