Department of Neurology
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The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia.
Biochemical and biophysical research communications Nov, 2009 | Pubmed ID: 19720050
Targeting the sphingolipid signaling pathway in stroke.
Stroke Apr, 2010 | Pubmed ID: 20185772
Pyrrolidine dithiocarbamate activates p38 MAPK and protects brain endothelial cells from apoptosis: a mechanism for the protective effect in stroke?
Neurochemical research Sep, 2010 | Pubmed ID: 20514517
Metabolism and regional cerebral blood volume in autoimmune inflammatory demyelinating lesions mimicking malignant gliomas.
Journal of neurology Jan, 2011 | Pubmed ID: 20803026
The perfect crime? CCSVI not leaving a trace in MS.
Journal of neurology, neurosurgery, and psychiatry Apr, 2011 | Pubmed ID: 21296899
Increased risk of hemorrhagic transformation in ischemic stroke occurring during warfarin anticoagulation: an experimental study in mice.
Stroke Apr, 2011 | Pubmed ID: 21330626
Treatment with the immunomodulator FTY720 does not promote spontaneous bacterial infections after experimental stroke in mice.
Experimental & translational stroke medicine Mar, 2011 | Pubmed ID: 21388542
Activation of sphingosine kinase 2 is an endogenous protective mechanism in cerebral ischemia.
Biochemical and biophysical research communications Sep, 2011 | Pubmed ID: 21872577
Anticoagulation with the oral direct thrombin inhibitor dabigatran does not enlarge hematoma volume in experimental intracerebral hemorrhage.
Circulation Oct, 2011 | Pubmed ID: 21911784
Recombinant activated coagulation factor VII and prothrombin complex concentrates are equally effective in reducing hematoma volume in experimental warfarin-associated intracerebral hemorrhage.
Stroke; a journal of cerebral circulation Jan, 2012 | Pubmed ID: 21998055
Warfarin anticoagulation exacerbates the risk of hemorrhagic transformation after rt-PA treatment in experimental stroke: therapeutic potential of PCC.
PloS one , 2011 | Pubmed ID: 22039437
Thrombolysis with recombinant tissue plasminogen activator under dabigatran anticoagulation in experimental stroke.
Annals of neurology May, 2012 | Pubmed ID: 22447744
Ceramide synthase 6 plays a critical role in the development of experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) Jun, 2012 | Pubmed ID: 22544924
No influence of dabigatran anticoagulation on hemorrhagic transformation in an experimental model of ischemic stroke.
PloS one , 2012 | Pubmed ID: 22911709
Graphite furnace atomic absorption spectrophotometry--a novel method to quantify blood volume in experimental models of intracerebral hemorrhage.
Journal of neuroscience methods Feb, 2013 | Pubmed ID: 23147006
Intracerebral haemorrhage associated with antithrombotic treatment: translational insights from experimental studies.
The Lancet. Neurology Apr, 2013 | Pubmed ID: 23518332
Thrombolysis in a stroke patient on dabigatran anticoagulation: case report and synopsis of published cases.
Case reports in neurology Jan, 2013 | Pubmed ID: 23626566
Blood levels of glial fibrillary acidic protein (GFAP) in patients with neurological diseases.
PloS one , 2013 | Pubmed ID: 23626774
FTY720 treatment in the convalescence period improves functional recovery and reduces reactive astrogliosis in photothrombotic stroke.
PloS one , 2013 | Pubmed ID: 23936150
The gap between trial data and clinical practice -- an analysis of case reports on bleeding complications occurring under dabigatran and rivaroxaban anticoagulation.
Cerebrovascular diseases (Basel, Switzerland) , 2013 | Pubmed ID: 24029592
FTY720 ameliorates acute ischemic stroke in mice by reducing thrombo-inflammation but not by direct neuroprotection.
Stroke; a journal of cerebral circulation Nov, 2013 | Pubmed ID: 24029635
Directional diffusion of corticospinal tract supports therapy decisions in idiopathic normal-pressure hydrocephalus.
Neuroradiology Jan, 2014 | Pubmed ID: 24158631
Astroglial proteins as diagnostic markers of acute intracerebral hemorrhage-pathophysiological background and clinical findings.
Translational stroke research Dec, 2010 | Pubmed ID: 24323552
PGE2/EP4 signaling in peripheral immune cells promotes development of experimental autoimmune encephalomyelitis.
Biochemical pharmacology Feb, 2014 | Pubmed ID: 24355567
Coadministration of FTY720 and rt-PA in an experimental model of large hemispheric stroke-no influence on functional outcome and blood-brain barrier disruption.
Experimental & translational stroke medicine Oct, 2013 | Pubmed ID: 24499647
Point-of-care coagulation testing for assessment of the pharmacodynamic anticoagulant effect of direct oral anticoagulant.
Therapeutic drug monitoring Oct, 2014 | Pubmed ID: 24577124
Prescription frequency and predictors for the use of novel direct oral anticoagulants for secondary stroke prevention in the first year after their marketing in Europe--a multicentric evaluation.
International journal of stroke : official journal of the International Stroke Society Jul, 2014 | Pubmed ID: 24828272
Fingolimod for the treatment of neurological diseases-state of play and future perspectives.
Frontiers in cellular neuroscience , 2014 | Pubmed ID: 25309325
Warfarin pretreatment reduces cell death and MMP-9 activity in experimental intracerebral hemorrhage.
Translational stroke research Apr, 2015 | Pubmed ID: 25424451
Recanalization therapies in acute ischemic stroke patients: impact of prior treatment with novel oral anticoagulants on bleeding complications and outcome.
Circulation Sep, 2015 | Pubmed ID: 26232277
Adherence to oral anticoagulant therapy in secondary stroke prevention - impact of the novel oral anticoagulants.
Patient preference and adherence , 2015 | Pubmed ID: 26648702
Treatment with FTY720 has no beneficial effects on short-term outcome in an experimental model of intracerebral hemorrhage.
Experimental & translational stroke medicine , 2016 | Pubmed ID: 26893821
Angiopoietin-2-induced blood-brain barrier compromise and increased stroke size are rescued by VE-PTP-dependent restoration of Tie2 signaling.
Acta neuropathologica May, 2016 | Pubmed ID: 26932603
Risk of long-term anticoagulation under sustained severe arterial hypertension: A translational study comparing warfarin and the new oral anticoagulant apixaban.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Apr, 2016 | Pubmed ID: 27189904
Estimating the Quantitative Demand of NOAC Antidote Doses on Stroke Units.
Cerebrovascular diseases (Basel, Switzerland) , 2016 | Pubmed ID: 27438461
T2-Imaging to Assess Cerebral Oxygen Extraction Fraction in Carotid Occlusive Disease: Influence of Cerebral Autoregulation and Cerebral Blood Volume.
PloS one , 2016 | Pubmed ID: 27560515
Reliability of infarct volumetry: Its relevance and the improvement by a software-assisted approach.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism Dec, 2016 | Pubmed ID: 27909266
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