Developmental Biology Program
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Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling.
Current biology : CB Sep, 2002 | Pubmed ID: 12372258
Hedgehog signalling in the mouse requires intraflagellar transport proteins.
Nature Nov, 2003 | Pubmed ID: 14603322
Analysis of mouse embryonic patterning and morphogenesis by forward genetics.
Proceedings of the National Academy of Sciences of the United States of America Apr, 2005 | Pubmed ID: 15755804
Cilia and Hedgehog responsiveness in the mouse.
Proceedings of the National Academy of Sciences of the United States of America Aug, 2005 | Pubmed ID: 16061793
Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates.
Development (Cambridge, England) Jan, 2006 | Pubmed ID: 16339192
All beta cells contribute equally to islet growth and maintenance.
PLoS biology Jul, 2007 | Pubmed ID: 17535113
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds.
Nature biotechnology Jul, 2008 | Pubmed ID: 18568017
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2.
Nature biotechnology Nov, 2008 | Pubmed ID: 18849973
A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog.
Cell stem cell Nov, 2009 | Pubmed ID: 19818703
Glucose and aging control the quiescence period that follows pancreatic beta cell replication.
Development (Cambridge, England) Oct, 2010 | Pubmed ID: 20823063
Human pluripotent stem cells: an emerging model in developmental biology.
Development (Cambridge, England) Feb, 2013 | Pubmed ID: 23362344
Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state.
Cell reports Mar, 2013 | Pubmed ID: 23478019
An iCRISPR platform for rapid, multiplexable, and inducible genome editing in human pluripotent stem cells.
Cell stem cell Aug, 2014 | Pubmed ID: 24931489
Stem cell epigenetics: looking forward.
Cell stem cell Jun, 2014 | Pubmed ID: 25032261
The iCRISPR platform for rapid genome editing in human pluripotent stem cells.
Methods in enzymology , 2014 | Pubmed ID: 25398343
Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells.
Nature biotechnology Jun, 2015 | Pubmed ID: 25798938
A CRISPR/Cas-Mediated Selection-free Knockin Strategy in Human Embryonic Stem Cells.
Stem cell reports Jun, 2015 | Pubmed ID: 26028531
Mechanisms underlying the formation of induced pluripotent stem cells.
Wiley interdisciplinary reviews. Developmental biology Jan-Feb, 2016 | Pubmed ID: 26383234
Genome Editing of Lineage Determinants in Human Pluripotent Stem Cells Reveals Mechanisms of Pancreatic Development and Diabetes.
Cell stem cell Jun, 2016 | Pubmed ID: 27133796
CRISPR/Cas9-Mediated Mutagenesis of Human Pluripotent Stem Cells in Defined Xeno-Free E8 Medium.
Methods in molecular biology (Clifton, N.J.) , 2017 | Pubmed ID: 27709569
CRISPR/Cas-Mediated Knockin in Human Pluripotent Stem Cells.
Methods in molecular biology (Clifton, N.J.) , 2017 | Pubmed ID: 27807834
The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells.
Cell stem cell Jan, 2017 | Pubmed ID: 27889317
Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development.
Cell stem cell Feb, 2017 | Pubmed ID: 28196600
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