Research and Development
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Site-directed mutagenesis studies of the hypoxia-inducible factor-1alpha DNA-binding domain.
Biochimica et biophysica acta Oct, 2002 | Pubmed ID: 12393189
Regulation of gene expression by oxygen: NF-kappaB and HIF-1, two extremes.
Free radical biology & medicine Nov, 2002 | Pubmed ID: 12398931
Modulation of interprotomer relationships is important for activation of dimeric calcium-sensing receptor.
The Journal of biological chemistry Apr, 2004 | Pubmed ID: 14729680
Hypoxia-inducible factor-1-dependent overexpression of myeloid cell factor-1 protects hypoxic cells against tert-butyl hydroperoxide-induced apoptosis.
The Journal of biological chemistry Mar, 2005 | Pubmed ID: 15611089
A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
BMC developmental biology , 2005 | Pubmed ID: 16033648
Mitoferrin is essential for erythroid iron assimilation.
Nature Mar, 2006 | Pubmed ID: 16511496
Urinary excretion of the acrylonitrile metabolite 2-cyanoethylmercapturic acid is correlated with a variety of biomarkers of tobacco smoke exposure and consumption.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals Feb, 2011 | Pubmed ID: 21108560
CYP1A1/1B1 and CYP2A6/2A13 activity is conserved in cultures of differentiated primary human tracheobronchial epithelial cells.
Toxicology in vitro : an international journal published in association with BIBRA Jun, 2011 | Pubmed ID: 21376804
An inter-laboratory comparison of urinary 3-hydroxypropylmercapturic acid measurement demonstrates good reproducibility between laboratories.
BMC research notes Oct, 2011 | Pubmed ID: 21985092
A comparative in vitro kinetic study of [14C]-eugenol and [14C]-methyleugenol activation and detoxification in human, mouse, and rat liver and lung fractions.
Xenobiotica; the fate of foreign compounds in biological systems May, 2012 | Pubmed ID: 22188410
Metabolic characterization of cell systems used in in vitro toxicology testing: lung cell system BEAS-2B as a working example.
Toxicology in vitro : an international journal published in association with BIBRA Sep, 2013 | Pubmed ID: 23669205
Urinary biomarkers of smokers' exposure to tobacco smoke constituents in tobacco products assessment: a fit for purpose approach.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals Sep, 2013 | Pubmed ID: 23902266
A correlation study applied to biomarkers of internal and effective dose for acrylonitrile and 4-aminobiphenyl in smokers.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals Jun, 2014 | Pubmed ID: 24754403
Nicotine, cotinine, and β-nicotyrine inhibit NNK-induced DNA-strand break in the hepatic cell line HepaRG.
Toxicology in vitro : an international journal published in association with BIBRA Jul, 2014 | Pubmed ID: 25075717
Nicotine, cotinine, and b-nicotyrine inhibit NNK-induced DNA-strand break in the hepatic cell line HepaRG.
Toxicology in vitro : an international journal published in association with BIBRA Oct, 2014 | Pubmed ID: 25221795
Application of CE-MS to a metabonomics study of human urine from cigarette smokers and non-smokers.
Bioanalysis Oct, 2014 | Pubmed ID: 25413705
Quantification of plasma microRNAs in a group of healthy smokers, ex-smokers and non-smokers and correlation to biomarkers of tobacco exposure.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals Mar, 2015 | Pubmed ID: 25598229
Targeted omics analyses, and metabolic enzyme activity assays demonstrate maintenance of key mucociliary characteristics in long term cultures of reconstituted human airway epithelia.
Toxicology in vitro : an international journal published in association with BIBRA Aug, 2015 | Pubmed ID: 25863282
Multiplatform serum metabolic phenotyping combined with pathway mapping to identify biochemical differences in smokers.
Bioanalysis Oct, 2016 | Pubmed ID: 27635669
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