Maciej Kmieciak

Cloning and characterization of two subunits of Arabidopsis thaliana nuclear cap-binding complex.

[The role of nuclear proteins that bind to 7-methyl-guanosine at the 5' end of RNA].

Emergence of immune escape variant of mammary tumors that has distinct proteomic profile and a reduced ability to induce "danger signals".

Comment on "Tumor progression can occur despite the induction of very high levels of self/tumor antigen-specific CD8+ T cells in patients with melanoma".

HER-2/neu antigen loss and relapse of mammary carcinoma are actively induced by T cell-mediated anti-tumor immune responses.

Tumor immunoediting and immunosculpting pathways to cancer progression.

Danger signals and nonself entity of tumor antigen are both required for eliciting effective immune responses against HER-2/neu positive mammary carcinoma: implications for vaccine design.

Signatures associated with rejection or recurrence in HER-2/neu-positive mammary tumors.

Radiofrequency thermal ablation of breast tumors combined with intralesional administration of IL-7 and IL-15 augments anti-tumor immune responses and inhibits tumor development and metastasis.

Does HER-2/neu antigen loss in metastatic breast tumors occur under immune pressure?

Adoptive transfer of HER2/neu-specific T cells expanded with alternating gamma chain cytokines mediate tumor regression when combined with the depletion of myeloid-derived suppressor cells.

Incubation of antigen-sensitized T lymphocytes activated with bryostatin 1 + ionomycin in IL-7 + IL-15 increases yield of cells capable of inducing regression of melanoma metastases compared to culture in IL-2.

The Arabidopsis CBP20 targets the cap-binding complex to the nucleus, and is stabilized by CBP80.

Human T cells express CD25 and Foxp3 upon activation and exhibit effector/memory phenotypes without any regulatory/suppressor function.

GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells.

CD4+ T cells inhibit the neu-specific CD8+ T-cell exhaustion during the priming phase of immune responses against breast cancer.

Tumor escape and progression of HER-2/neu negative breast cancer under immune pressure.

A signature of immune function genes associated with recurrence-free survival in breast cancer patients.

Activated NKT cells and NK cells render T cells resistant to myeloid-derived suppressor cells and result in an effective adoptive cellular therapy against breast cancer in the FVBN202 transgenic mouse.

CD44(+)/CD24(-/low) cancer stem/progenitor cells are more abundant in triple-negative invasive breast carcinoma phenotype and are associated with poor outcome.

The role of Tyk2 in regulation of breast cancer growth.

Distinct signatures of the immune responses in low risk versus high risk neuroblastoma.