Huijuan You

School of Pharmacy,
Tongji Medical College,
School of Pharmacy, Tongji Medical College

Huazhong University of Science and Technology

BIOGRAPHY

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PUBLICATIONS

Winding single-molecule double-stranded DNA on a nanometer-sized reel.

Nucleic acids research Oct, 2012 | Pubmed ID: 22772992

Dynamics and stability of polymorphic human telomeric G-quadruplex under tension.

Nucleic acids research Jul, 2014 | Pubmed ID: 25013179

Stability and kinetics of c-MYC promoter G-quadruplexes studied by single-molecule manipulation.

Journal of the American Chemical Society Feb, 2015 | Pubmed ID: 25654467

Torque transmission mechanism via DELSEED loop of F1-ATPase.

Biophysical journal Mar, 2015 | Pubmed ID: 25762326

RHAU helicase stabilizes G4 in its nucleotide-free state and destabilizes G4 upon ATP hydrolysis.

Nucleic acids research Jan, 2017 | Pubmed ID: 28069994

Single-molecule imaging and manipulation of biomolecular machines and systems.

Biochimica et biophysica acta Aug, 2017 | Pubmed ID: 28789884

INSTITUTIONS

Huazhong University of Science and Technology

JOVE ARTICLES

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers

Huijuan You^*,1,

Shimin Le^*,2,3,

Hu Chen^2,4,

Linyan Qin¹,

Jie Yan^2,4,5

¹School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology,

²Mechanobiology Institute, National University of Singapore,

³Department of Physics, National University of Singapore,

⁴Research Institute for Biomimetics and Soft Matter, Fujian Provincial Key Lab for Soft Functional Materials Research, Department of Physics, Xiamen University,

⁵Center for Bioimaging Sciences, National University of Singapore

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Huijuan You

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Huazhong University of Science and Technology

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers

School of Pharmacy,
Tongji Medical College,
School of Pharmacy, Tongji Medical College