Tetsushi Furukawa

Functional Modulation of Cardiac ATP-Sensitive K(+) Channels.

Ion channel remodeling in cardiac hypertrophy is prevented by blood pressure reduction without affecting heart weight increase in rats with abdominal aortic banding.

Electrophysiological effects of ginseng and ginsenoside Re in guinea pig ventricular myocytes.

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

[Various functions of ClC-type Cl- channels].

Nitric oxide-dependent modulation of the delayed rectifier K+ current and the L-type Ca2+ current by ginsenoside Re, an ingredient of Panax ginseng, in guinea-pig cardiomyocytes.

Block of HERG current expressed in HEK293 cells by the Na+-channel blocker cibenzoline.

Aquaporin-2 trafficking is regulated by PDZ-domain containing protein SPA-1.

Role of nitric oxide in Ca2+ sensitivity of the slowly activating delayed rectifier K+ current in cardiac myocytes.

Nontranscriptional regulation of cardiac repolarization currents by testosterone.

Potassium channel remodeling in cardiac hypertrophy.

Ginsenoside Re, a main phytosterol of Panax ginseng, activates cardiac potassium channels via a nongenomic pathway of sex hormones.

T75M-KCNJ2 mutation causing Andersen-Tawil syndrome enhances inward rectification by changing Mg2+ sensitivity.

Regulation of cardiac ion channels via non-genomic action of sex steroid hormones: implication for the gender difference in cardiac arrhythmias.

Acute effects of oestrogen on the guinea pig and human IKr channels and drug-induced prolongation of cardiac repolarization.

Bioluminescent indicators for Ca2+ based on split Renilla luciferase complementation in living cells.

Non-genomic regulation of cardiac ion channels by sex hormones.

KCNE variants reveal a critical role of the beta subunit carboxyl terminus in PKA-dependent regulation of the IKs potassium channel.

Redox- and calmodulin-dependent S-nitrosylation of the KCNQ1 channel.

A receptor-independent effect of estrone sulfate on the HERG channel.

New aspects for the treatment of cardiac diseases based on the diversity of functional controls on cardiac muscles: acute effects of female hormones on cardiac ion channels and cardiac repolarization.

A genetically encoded bioluminescent indicator for the sodium channel activity in living cells.

High glucose concentrations impair the activation of K+ channels and proteases in undifferentiated THP-1 monocytes.

A Combined Approach Using Patch-Clamp Study and Computer Simulation Study for Understanding Long QT Syndrome and TdP in Women.

Acute effects of sex steroid hormones on susceptibility to cardiac arrhythmias: a simulation study.

Circulating KCNH2 current-activating factor in patients with heart failure and ventricular tachyarrhythmia.

[Atrial fibrillation and inflammation].

Meta-analysis identifies six new susceptibility loci for atrial fibrillation.

Sex and gender aspects in antiarrhythmic therapy.

Stretch of atrial myocytes stimulates recruitment of macrophages via ATP released through gap-junction channels.

Effects of an hERG activator, ICA-105574, on electrophysiological properties of canine hearts.

Non-genomic action of sex steroid hormones and cardiac repolarization.

Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation.

Image-based evaluation of contraction-relaxation kinetics of human-induced pluripotent stem cell-derived cardiomyocytes: Correlation and complementarity with extracellular electrophysiology.

Endothelin-1 induces myofibrillar disarray and contractile vector variability in hypertrophic cardiomyopathy-induced pluripotent stem cell-derived cardiomyocytes.

Severe iatrogenic bradycardia related to the combined use of beta-blocking agents and sodium channel blockers.

Enhancement of Spontaneous Activity by HCN4 Overexpression in Mouse Embryonic Stem Cell-Derived Cardiomyocytes - A Possible Biological Pacemaker.

Genetic defects in a His-Purkinje system transcription factor, IRX3, cause lethal cardiac arrhythmias.

Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator.

High-fat diet increases vulnerability to atrial arrhythmia by conduction disturbance via miR-27b.

Intravital imaging of Ca(2+) signals in lymphocytes of Ca(2+) biosensor transgenic mice: indication of autoimmune diseases before the pathological onset.

Sall1 transiently marks undifferentiated heart precursors and regulates their fate.

Oxidative Stress Induced Ventricular Arrhythmia and Impairment of Cardiac Function in Nos1ap Deleted Mice.

A distribution analysis of action potential parameters obtained from patch-clamped human stem cell-derived cardiomyocytes.

Novel Dielectric Coagulometer Identifies Hypercoagulability in Patients with a High CHADS2 Score without Atrial Fibrillation.

Long-Term Prognosis of Catecholaminergic Polymorphic Ventricular Tachycardia Patients With Ryanodine Receptor (RYR2) Mutations.

Sex hormonal regulation of cardiac ion channels in drug-induced QT syndromes.

Embryonic type Nachannel β-subunit, SCN3B masks the disease phenotype of Brugada syndrome.

[Therapeutic strategy targeting membrane molecular meshanosensing.]

Association of ZFHX3 gene variation with atrial fibrillation, cerebral infarction, and lung thromboembolism: An autopsy study.

Clinical utility and functional analysis of variants in atrial fibrillation-associated locus 4q25.

Genetic Variants Associated With Susceptibility to Atrial Fibrillation in a Japanese Population.

Identification of six new genetic loci associated with atrial fibrillation in the Japanese population.

IRX3 variant as a modifier of Brugada syndrome with frequent ventricular fibrillation.

Overexpression of KCNJ2 in induced pluripotent stem cell-derived cardiomyocytes for the assessment of QT-prolonging drugs.

Chromosome 4q25 variants and recurrence after second-generation cryoballoon ablation in patients with paroxysmal atrial fibrillation.

Association of the Clinical and Genetic Factors With Superior Vena Cava Arrhythmogenicity in Atrial Fibrillation.

Calcification of joints and arteries with novel NT5E mutations with involvement of upper extremity arteries.

Flecainide ameliorates arrhythmogenicity through NCX flux in Andersen-Tawil syndrome-iPS cell-derived cardiomyocytes.

Combined Analysis of Human and Experimental Murine Samples Identified Novel Circulating MicroRNAs as Biomarkers for Atrial Fibrillation.