Kurt R. Zinn

Targeted radiotherapy with [(90)Y]-SMT 487 in mice bearing human nonsmall cell lung tumor xenografts induced to express human somatostatin receptor subtype 2 with an adenoviral vector.

Gamma camera dual imaging with a somatostatin receptor and thymidine kinase after gene transfer with a bicistronic adenovirus in mice.

The type 2 human somatostatin receptor as a platform for reporter gene imaging.

In vivo molecular chemotherapy and noninvasive imaging with an infectivity-enhanced adenovirus.

Glomerular targeting of acidic fibroblast growth factor-1 in renal transplanted rats.

A non-invasive approach for monitoring breast tumor cells during therapeutic intervention.

Enhancement of MHC class II-restricted responses by receptor-mediated uptake of peptide antigens.

Inhibition of T cell responses by transferrin-coupled competitor peptides.

Alternatively spliced FGFR-1 isoform signaling differentially modulates endothelial cell responses to peroxynitrite.

Blood-based screening and light based imaging for the early detection and monitoring of ovarian cancer xenografts.

Fc gamma Rs modulate cytotoxicity of anti-Fas antibodies: implications for agonistic antibody-based therapeutics.

Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus.

Sinusoidal endothelium in mouse liver show rapid and saturable binding of Jo2 anti-Fas antibody.

Gene expression imaging with radiolabeled peptides.

Radiotargeted gene therapy.

Intraperitoneal pretarget radioimmunotherapy with CC49 fusion protein.

In vivo imaging of hepatic growth hormone signaling.

Deficiency of P-selectin or P-selectin glycoprotein ligand-1 leads to accelerated development of glomerulonephritis and increased expression of CC chemokine ligand 2 in lupus-prone mice.

Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host.

Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung.

High-resolution single-photon emission computed tomography and X-ray computed tomography imaging of Tc-99m-labeled anti-DR5 antibody in breast tumor xenografts.

Use of fluorescent labeled anti-epidermal growth factor receptor antibody to image head and neck squamous cell carcinoma xenografts.

Detection of early changes in renal function using 99mTc-MAG3 imaging in a murine model of ischemia-reperfusion injury.

Combination treatment with TRA-8 anti death receptor 5 antibody and CPT-11 induces tumor regression in an orthotopic model of pancreatic cancer.

Neural progenitor cell transplantation and imaging in a large animal model.

TRA-8 anti-DR5 monoclonal antibody and gemcitabine induce apoptosis and inhibit radiologically validated orthotopic pancreatic tumor growth.

Noninvasive bioluminescence imaging in small animals.

Fluorescent labeled anti-EGFR antibody for identification of regional and distant metastasis in a preclinical xenograft model.

Endotoxin-induced proteolytic reduction in hepatic growth hormone (GH) receptor: a novel mechanism for GH insensitivity.

Treatment of human colon cancer xenografts with TRA-8 anti-death receptor 5 antibody alone or in combination with CPT-11.

Systemic osteoprotegerin gene therapy restores tumor-induced bone loss in a therapeutic model of breast cancer bone metastasis.

Stereomicroscopic fluorescence imaging of head and neck cancer xenografts targeting CD147.

Breast tumor xenografts: diffusion-weighted MR imaging to assess early therapy with novel apoptosis-inducing anti-DR5 antibody.

Genetic modification of adeno-associated viral vector type 2 capsid enhances gene transfer efficiency in polarized human airway epithelial cells.

Early therapy evaluation of combined anti-death receptor 5 antibody and gemcitabine in orthotopic pancreatic tumor xenografts by diffusion-weighted magnetic resonance imaging.

Effector and suppressor roles for LFA-1 during the development of experimental autoimmune encephalomyelitis.

Targeting of adenovirus serotype 5 pseudotyped with short fiber from serotype 41 to c-erbB2-positive cells using bispecific single-chain diabody.

Gammadelta T cells in EAE: early trafficking events and cytokine requirements.

Bioluminescence-based visualization of CD4 T cell dynamics using a T lineage-specific luciferase transgenic model.

Death receptor 5 agonist TRA8 in combination with the bisphosphonate zoledronic acid attenuated the growth of breast cancer metastasis.

Novel infectivity-enhanced oncolytic adenovirus with a capsid-incorporated dual-imaging moiety for monitoring virotherapy in ovarian cancer.

Deletion of IGF-I receptor (IGF-IR) in primary osteoblasts reduces GH-induced STAT5 signaling.

Noninvasive monitoring of mRFP1- and mCherry-labeled oncolytic adenoviruses in an orthotopic breast cancer model by spectral imaging.

Determination of breast cancer response to bevacizumab therapy using contrast-enhanced ultrasound and artificial neural networks.

DCE-MRI detects early vascular response in breast tumor xenografts following anti-DR5 therapy.

Optical imaging predicts tumor response to anti-EGFR therapy.

Single photon emission computed tomography demonstrated efficacy of 17β-estradiol therapy in male rats after trauma-hemorrhage and extended hypotension.

A genetic strategy for combined screening and localized imaging of breast cancer.

Prevention of diabetic nephropathy in Ins2(+/)⁻(AkitaJ) mice by the mitochondria-targeted therapy MitoQ.

Tamoxifen inhibits malignant peripheral nerve sheath tumor growth in an estrogen receptor-independent manner.

Components of a curriculum for molecular imaging scientists.

(18)F-FDG PET/CT Imaging Detects Therapy Efficacy of Anti-EMMPRIN Antibody and Gemcitabine in Orthotopic Pancreatic Tumor Xenografts.

Early therapy evaluation of combined cetuximab and irinotecan in orthotopic pancreatic tumor xenografts by dynamic contrast-enhanced magnetic resonance imaging.

Model system using controlled receptor expression for evaluating targeted ultrasound contrast agents.

A triple-targeted ultrasound contrast agent provides improved localization to tumor vasculature.

Extracelluar matrix metalloproteinase as a novel target for pancreatic cancer therapy.

Effect of anti-DR5 and chemotherapy on basal-like breast cancer.

Inhibitory GH receptor extracellular domain monoclonal antibodies: three-dimensional epitope mapping.

Dual Combination Therapy Targeting DR5 and EMMPRIN in Pancreatic Adenocarcinoma.