Yu-Hwai Tsai

Department of Internal Medicine,
Division of Gastroenterology,
Department of Internal Medicine, Division of Gastroenterology

University of Michigan

BIOGRAPHY

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PUBLICATIONS

Temporally distinct requirements for endothelin receptor B in the generation and migration of gut neural crest stem cells.

Neuron Dec, 2003 | Pubmed ID: 14659091

Extrarenal ETB plays a significant role in controlling cardiovascular responses to high dietary sodium in rats.

Hypertension (Dallas, Tex. : 1979) May, 2005 | Pubmed ID: 15809364

Dynamic changes in the proximal gut neural crest stem cell population are associated with successful development of the distal enteric nervous system in rats.

Pediatric research Oct, 2005 | Pubmed ID: 16189186

Chronic high-sodium diet increases aortic wall endothelin-1 expression in a blood pressure-independent fashion in rats.

Experimental biology and medicine (Maywood, N.J.) Jun, 2006 | Pubmed ID: 16741004

Postnatal intestinal engraftment of prospectively selected enteric neural crest stem cells in a rat model of Hirschsprung disease.

Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society Apr, 2011 | Pubmed ID: 21199176

Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.

Development (Cambridge, England) Feb, 2012 | Pubmed ID: 22190634

Distinct TCR signaling pathways drive proliferation and cytokine production in T cells.

Nature immunology Feb, 2013 | Pubmed ID: 23377202

A Lactobacillus rhamnosus GG-derived soluble protein, p40, stimulates ligand release from intestinal epithelial cells to transactivate epidermal growth factor receptor.

The Journal of biological chemistry Oct, 2013 | Pubmed ID: 24043629

ADAM10 regulates Notch function in intestinal stem cells of mice.

Gastroenterology Oct, 2014 | Pubmed ID: 25038433

Modelling human development and disease in pluripotent stem-cell-derived gastric organoids.

Nature Dec, 2014 | Pubmed ID: 25363776

In vitro generation of human pluripotent stem cell derived lung organoids.

eLife , 2015 | Pubmed ID: 25803487

Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo.

Stem cell reports Jun, 2015 | Pubmed ID: 26050928

Loss of ADAM17-Mediated Tumor Necrosis Factor Alpha Signaling in Intestinal Cells Attenuates Mucosal Atrophy in a Mouse Model of Parenteral Nutrition.

Molecular and cellular biology Nov, 2015 | Pubmed ID: 26283731

Generation of tissue-engineered small intestine using embryonic stem cell-derived human intestinal organoids.

Biology open Oct, 2015 | Pubmed ID: 26459240

Lumen Formation Is an Intrinsic Property of Isolated Human Pluripotent Stem Cells.

Stem cell reports Dec, 2015 | Pubmed ID: 26626176

A Dynamic WNT/β-CATENIN Signaling Environment Leads to WNT-Independent and WNT-Dependent Proliferation of Embryonic Intestinal Progenitor Cells.

Stem cell reports Nov, 2016 | Pubmed ID: 27720905

In vitro patterning of pluripotent stem cell-derived intestine recapitulates in vivo human development.

Development (Cambridge, England) 03, 2017 | Pubmed ID: 27927684

LGR4 and LGR5 Function Redundantly During Human Endoderm Differentiation.

Cellular and molecular gastroenterology and hepatology Sep, 2016 | Pubmed ID: 28078320

Interdependency of EGF and GLP-2 Signaling in Attenuating Mucosal Atrophy in a Mouse Model of Parenteral Nutrition.

Cellular and molecular gastroenterology and hepatology May, 2017 | Pubmed ID: 28462383

Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium.

eLife Nov, 2017 | Pubmed ID: 29110754

INSTITUTIONS

University of Michigan

JOVE ARTICLES

Real-time Measurement of Epithelial Barrier Permeability in Human Intestinal Organoids

David R. Hill¹,

Sha Huang¹,

Yu-Hwai Tsai¹,

Jason R. Spence^1,2,

Vincent B. Young^1,3

¹Department of Internal Medicine, Division of Gastroenterology, University of Michigan,

²Department of Cell and Developmental Biology, University of Michigan,

³Department of Internal Medicine, Division of Infectious Disease, University of Michigan

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Yu-Hwai Tsai

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Department of Internal Medicine,Division of Gastroenterology,Department of Internal Medicine, Division of Gastroenterology

University of Michigan

Real-time Measurement of Epithelial Barrier Permeability in Human Intestinal Organoids

Department of Internal Medicine,
Division of Gastroenterology,
Department of Internal Medicine, Division of Gastroenterology