Department of Neurosciences,
Experimental Neurology,
Department of Neurosciences, Experimental Neurology
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Developments in treatments for amyotrophic lateral sclerosis via intracerebroventricular or intrathecal delivery.
Expert opinion on investigational drugs Jul, 2014 | Pubmed ID: 24816247
Prevention of intestinal obstruction reveals progressive neurodegeneration in mutant TDP-43 (A315T) mice.
Molecular neurodegeneration Jun, 2014 | Pubmed ID: 24938805
The role of oligodendroglial dysfunction in amyotrophic lateral sclerosis.
Neurodegenerative disease management , 2014 | Pubmed ID: 25095817
Cochlear supporting cell transdifferentiation and integration into hair cell layers by inhibition of ephrin-B2 signalling.
Nature communications Apr, 2015 | Pubmed ID: 25923646
Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS.
Nature neuroscience Sep, 2015 | Pubmed ID: 26308983
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD.
Scientific reports Feb, 2016 | Pubmed ID: 26869068
Prospective Validation of 18F-FDG Brain PET Discriminant Analysis Methods in the Diagnosis of Amyotrophic Lateral Sclerosis.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine Aug, 2016 | Pubmed ID: 26940764
Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis.
JAMA neurology Jul, 2016 | Pubmed ID: 27244217
Genetic ablation of IP3 receptor 2 increases cytokines and decreases survival of SOD1G93A mice.
Human molecular genetics 08, 2016 | Pubmed ID: 27378687
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.
Nature genetics Sep, 2016 | Pubmed ID: 27455348
C9orf72 expansion differentially affects males with spinal onset amyotrophic lateral sclerosis.
Journal of neurology, neurosurgery, and psychiatry Apr, 2017 | Pubmed ID: 27663272
ATXN2 trinucleotide repeat length correlates with risk of ALS.
Neurobiology of aging Mar, 2017 | Pubmed ID: 28017481
Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics.
Molecular cell Mar, 2017 | Pubmed ID: 28306503
Progranulin functions as a cathepsin D chaperone to stimulate axonal outgrowth in vivo.
Human molecular genetics 08, 2017 | Pubmed ID: 28453791
Identification and characterization of Nanobodies targeting the EphA4 receptor.
The Journal of biological chemistry 07, 2017 | Pubmed ID: 28526745
Prognostic value of clinical and electrodiagnostic parameters at time of diagnosis in patients with amyotrophic lateral sclerosis.
Amyotrophic lateral sclerosis & frontotemporal degeneration Aug, 2017 | Pubmed ID: 28631957
Amyotrophic lateral sclerosis.
Nature reviews. Disease primers Oct, 2017 | Pubmed ID: 28980624
Inhibition of histone deacetylase 6 (HDAC6) protects against vincristine-induced peripheral neuropathies and inhibits tumor growth.
Neurobiology of disease Mar, 2018 | Pubmed ID: 29197621
Reconsidering the causality of TIA1 mutations in ALS.
Amyotrophic lateral sclerosis & frontotemporal degeneration 02, 2018 | Pubmed ID: 29235362
A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism.
Acta neuropathologica Mar, 2018 | Pubmed ID: 29302778
Elongator subunit 3 (ELP3) modifies ALS through tRNA modification.
Human molecular genetics Apr, 2018 | Pubmed ID: 29415125
HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease.
Brain : a journal of neurology Feb, 2018 | Pubmed ID: 29415205
Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.
Neuron Mar, 2018 | Pubmed ID: 29566793
Conditional deletion of Id2 or Notch1 in oligodendrocyte progenitor cells does not ameliorate disease outcome in SOD1 mice.
Neurobiology of aging Aug, 2018 | Pubmed ID: 29689424
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