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Institut de Chimie Moléculaire de Reims UMR 7312
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Spirocyclopropyl pyrrolidines as a new series of alpha-L-fucosidase inhibitors.
Bioorganic & medicinal chemistry Jun, 2006 | Pubmed ID: 16488612
Thermodynamic and spectroscopic studies of Cu(II) and Ni(II) complexes with a new proline-threonine dipeptide ligand.
Journal of inorganic biochemistry Jul, 2008 | Pubmed ID: 18314195
The spirocyclopropyl moiety as a methyl surrogate in the structure of l-fucosidase and l-rhamnosidase inhibitors.
Bioorganic & medicinal chemistry Dec, 2009 | Pubmed ID: 19875298
Synthesis, physico-chemical properties and complexing abilities of new amphiphilic ligands from D-galacturonic acid.
Carbohydrate research Apr, 2010 | Pubmed ID: 20170906
Chitin synthase, a fungal glycosyltransferase that is a valuable antifungal target.
Chimia , 2011 | Pubmed ID: 21469445
Highly selective indium mediated allylation of unprotected pentosylamines.
Organic letters Mar, 2012 | Pubmed ID: 22360647
Iminosugar-ferrocene conjugates as potential anticancer agents.
Organic & biomolecular chemistry Aug, 2012 | Pubmed ID: 22717621
α-L-fucosidase inhibition by pyrrolidine-ferrocene hybrids: rationalization of ligand-binding properties by structural studies.
Chemistry (Weinheim an der Bergstrasse, Germany) Jul, 2013 | Pubmed ID: 23740878
Trifluoromethide as a strong base: [CF3-] mediates dichloromethylation of nitrones by proton abstraction from the solvent.
The Journal of organic chemistry Nov, 2013 | Pubmed ID: 24111552
Exploiting the hydrophobic terrain in fucosidases with aryl-substituted pyrrolidine iminosugars.
Chembiochem : a European journal of chemical biology Jan, 2015 | Pubmed ID: 25427942
Synthesis of 2-carboxymethyl polyhydroxyazepanes and their evaluation as glycosidase inhibitors.
Bioorganic chemistry Feb, 2015 | Pubmed ID: 25462622
Glycosidase inhibitors from the roots of Glyphaea brevis.
Phytochemistry Jan, 2015 | Pubmed ID: 25468536
A second-generation ferrocene-iminosugar hybrid with improved fucosidase binding properties.
Bioorganic & medicinal chemistry letters Mar, 2016 | Pubmed ID: 26897594
Expanding the library of divalent fucosidase inhibitors with polyamino and triazole-benzyl bridged bispyrrolidines.
Organic & biomolecular chemistry Mar, 2016 | Pubmed ID: 26906450
Exploring the divalent effect in fucosidase inhibition with stereoisomeric pyrrolidine dimers.
Organic & biomolecular chemistry May, 2016 | Pubmed ID: 27138139
Generation of ϵ,ϵ-Difluorinated Metal-Pentadienyl Species through Lanthanide-Mediated C-F Activation.
Chemistry (Weinheim an der Bergstrasse, Germany) Nov, 2017 | Pubmed ID: 28980352
Synthesis and glycosidase inhibition potency of all-trans substituted 1-C-perfluoroalkyl iminosugars.
Carbohydrate research Jul, 2018 | Pubmed ID: 29777947
Université de Reims Champagne Ardenne
Tarun Kumar1,2,
Amira Ben Hassine1,
Agathe Martinez1,
Dominique Harakat1,
Sylviane Chevreux1,
Fabien Massicot1,
Marc Taillefer2,
Jean-Bernard Behr1,
Jean-Luc Vasse1,
Florian Jaroschik1,2
1Institut de Chimie Moléculaire de Reims UMR 7312, Université de Reims Champagne Ardenne,
2Institut Charles Gerhardt Montpellier UMR 5253, Ecole Nationale Supérieure de Chimie de Montpellier
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