Edward N. Harris

Department of Biochemistry, University of Nebraska, Lincoln

Affiliated withUniversity of Nebraska, Lincoln University of Nebraska

Research Area

BiologyBiochemistry

Biography

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JoVE Journal Publications

Article Total : 2	Year
Publication title	2011
Publication title	2018

Other Publications

Article	Year
Endocytic function, glycosaminoglycan specificity, and antibody sensitivity of the recombinant human 190-kDa hyaluronan receptor for endocytosis (HARE). The Journal of biological chemistry\| PubMed ID: 15208308	2004
Expression, processing, and glycosaminoglycan binding activity of the recombinant human 315-kDa hyaluronic acid receptor for endocytosis (HARE). The Journal of biological chemistry\| PubMed ID: 17145755	2007
The hyaluronan receptor for endocytosis mediates hyaluronan-dependent signal transduction via extracellular signal-regulated kinases. The Journal of biological chemistry\| PubMed ID: 18387958	2008
The human hyaluronan receptor for endocytosis (HARE/Stabilin-2) is a systemic clearance receptor for heparin. The Journal of biological chemistry\| PubMed ID: 18434317	2008
The ligand-binding profile of HARE: hyaluronan and chondroitin sulfates A, C, and D bind to overlapping sites distinct from the sites for heparin, acetylated low-density lipoprotein, dermata... Glycobiology\| PubMed ID: 18499864	2008
The cytoplasmic domain of the hyaluronan receptor for endocytosis (HARE) contains multiple endocytic motifs targeting coated pit-mediated internalization. The Journal of biological chemistry\| PubMed ID: 18539600	2008
Rat and human HARE/stabilin-2 are clearance receptors for high- and low-molecular-weight heparins. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 19359419	2009
N-Glycans on the link domain of human HARE/Stabilin-2 are needed for hyaluronan binding to purified ecto-domain, but not for cellular endocytosis of hyaluronan. Glycobiology\| PubMed ID: 20466649	2010
Probing structural selectivity of synthetic heparin binding to Stabilin protein receptors. The Journal of biological chemistry\| PubMed ID: 22547069	2012
The hyaluronan receptor for endocytosis (HARE) activates NF-κB-mediated gene expression in response to 40-400-kDa, but not smaller or larger, hyaluronans. The Journal of biological chemistry\| PubMed ID: 23530033	2013
Homogeneous low-molecular-weight heparins with reversible anticoagulant activity. Nature chemical biology\| PubMed ID: 24561662	2014
Tissue-specific splice variants of HARE/Stabilin-2 are expressed in bone marrow, lymph node, and spleen. Biochemical and biophysical research communications\| PubMed ID: 25446080	2015
In vivo selection to identify bacterial strains with enhanced ecological performance in synbiotic applications. Applied and environmental microbiology\| PubMed ID: 25616794	2015
HARE-Mediated Endocytosis of Hyaluronan and Heparin Is Targeted by Different Subsets of Three Endocytic Motifs. International journal of cell biology\| PubMed ID: 25883656	2015
Interrogating Endogenous Protein Phosphatase Activity with Rationally Designed Chemosensors. ACS chemical biology\| PubMed ID: 26580981	2016
Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver. Nucleic acids research\| PubMed ID: 26908652	2016
Alcoholic vs non-alcoholic fatty liver in rats: distinct differences in endocytosis and vesicle trafficking despite similar pathology. BMC gastroenterology\| PubMed ID: 26924554	2016
Activation of ERK and NF-κB during HARE-Mediated Heparin Uptake Require Only One of the Four Endocytic Motifs. PloS one\| PubMed ID: 27100626	2016
SECs (Sinusoidal Endothelial Cells), Liver Microenvironment, and Fibrosis. BioMed research international\| PubMed ID: 28293634	2017
Antisense Oligonucleotides: Treatment Strategies and Cellular Internalization. RNA & disease (Houston, Tex.)\| PubMed ID: 28374018	2016
Quantification of Cell Signaling Networks Using Kinase Activity Chemosensors. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 28730472	2017