localization-quantification-begomoviruses-whitefly-tissues

Localization and Quantification of Begomoviruses in Whitefly Tissues by Immunofluorescence and Quantitative PCR

Begomoviruses (genus Begomovirus, family Geminiviridae) are transmitted by whiteflies of the Bemisia tabaci complex in a persistent, circulative manner. ...

Zhejiang University

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To measure the muscle pressure exerted on the deciduous normal occlusion and to explore the relationship between the denture,occlusion, skeleton and muscle pressure.

[Study of muscle pressure exerted on deciduous normal occlusion].

Pour mesurer la pression musculaire exerc&eacute;e sur l&#39;occlusion normale &agrave; feuilles caduques et &agrave; explorer la relation entre la proth&egrave;se dentaire, occlusion, pression de squelette et des muscles.

[&Eacute;tude de muscle pression exerc&eacute;e sur les feuillus occlusion normale].

[Studie der Muskel Druck auf Laub-Normokklusion ausge&#xFC;bt].

Per misurare la pressione muscolare esercitata sull&#39;occlusione decidua normale e per esplorare il rapporto tra la protesi, l&#39;occlusione, la pressione dello scheletro e del muscolo.

[Studio di muscolo pressione esercitata sull&#39;occlusione decidua normale].

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Para medir la presi&oacute;n del m&uacute;sculo ejercida sobre la oclusi&oacute;n normal de hojas caduca y explorar la relaci&oacute;n entre la pr&oacute;tesis, oclusi&oacute;n, presi&oacute;n de esqueleto y m&uacute;sculo.

[Estudio de presi&oacute;n muscular caducifolia oclusi&oacute;n normal].

&#x8FD9;&#x9879;&#x7814;&#x7A76;&#x8BC4;&#x4F30;&#x6B63;&#x5E38;&#x843D;&#x53F6;&#x7259;&#x5217;&#x548C;&#x808C;&#x8089;&#x529B;&#x91CF;&#x3001; &#x6027;&#x522B;&#x548C;&#x53E3;&#x8154;&#x529F;&#x80FD;&#x4E4B;&#x95F4;&#x7684;&#x5173;&#x7CFB;&#x53D7;&#x529B;&#x7684;&#x5206;&#x5E03;&#x7279;&#x5F81;&#x3002;&#x6D4B;&#x91CF;&#x538B;&#x529B;&#x4F5C;&#x51FA;&#x4E86;&#x7531;&#x4F5C;&#x8005;&#x8BBE;&#x8BA1;&#x7684;&#x4E00;&#x4E2A;&#x8BA1;&#x7B97;&#x673A;&#x8F85;&#x52A9;&#x53E3;&#x5468;&#x6D4B;&#x529B;&#x7CFB;&#x7EDF;&#x3002;&#x4E3B;&#x9898;&#x5934;&#x4F4D;&#x7F6E;&#x5904;&#x4E8E;&#x81EA;&#x7136;&#x5934;&#x4F4D;&#x7684;&#x72B6;&#x6001;&#x548C;&#x53E3;&#x8154;&#x529F;&#x80FD;&#x662F;&#x5728;&#x4F11;&#x606F;&#x6216;&#x7528;&#x541E;&#x54BD;&#x65F6;&#x6D4B;&#x91CF;&#x90E8;&#x961F;&#x3002;&#x7ED3;&#x679C;&#x8868;&#x660E;&#x4ECE;&#x5634;&#x5507;&#x3001; &#x8138;&#x988A;&#x548C;&#x820C;&#x5934;&#x5728;&#x5176;&#x4F59;&#x90E8;&#x961F;&#x7EA6; 37 208 N/m2&#xFF0C;&#x800C;&#x671F;&#x95F4;&#x541E;&#x54BD;&#x538B;&#x529B;&#x662F;&#x5173;&#x4E8E; 1009&#x5E74; 1679 N/m2&#x3002;&#x5904;&#x4E8E;&#x9759;&#x6B62;&#x72B6;&#x6001;&#xFF0C;&#x4ECE;&#x5634;&#x5507;&#x548C;&#x8138;&#x988A;&#x538B;&#x529B;&#x9AD8;&#x4E8E;&#x4ECE;&#x820C; (P &lt;.05), &#x800C;&#x541E;&#x54BD;&#xFF0C;&#x671F;&#x95F4;&#x7684;&#x820C;&#x4FA7;&#x538B;&#x529B;&#x662F;&#x7EDF;&#x8BA1;&#x4E0A;&#x7684;&#x8F83;&#x5927; (P &lt;.001&#xFF09;&#x3002;&#x808C;&#x8089;&#x538B;&#x529B;&#x4E0E;&#x6027;&#x522B;&#x4E4B;&#x95F4;&#x5B58;&#x5728;&#x660E;&#x663E;&#x7684;&#x76F8;&#x5173;&#x6027;&#x3002;&#x5904;&#x4E8E;&#x9759;&#x6B62;&#x72B6;&#x6001;&#xFF0C;&#x5F53;&#x4ECE;&#x53CC;&#x988A;&#x7537;&#x5B69;&#x7684;&#x6B66;&#x529B;&#x662F;&#x6BD4;&#x5973;&#x5B69;&#x9AD8; (P &lt;.05) &#x4F46;&#x541E;&#x54BD;&#x90A3;&#x7537;&#x5B69;&#x7684;&#x5507;&#x538B;&#x529B;&#x5728;&#x7EDF;&#x8BA1;&#x5B66;&#x4E0A;&#x9AD8;&#x4E8E;&#x5973;&#x5B69;&#x7684; (P &lt;.01&#xFF09;&#x3002;&#x5F97;&#x51FA;&#x7684;&#x7ED3;&#x8BBA;&#x662F; (1) &#x4E73;&#x7259;&#x4E0D;&#x5728;&#x7684;&#x5916;&#x90E8;&#x548C;&#x5185;&#x90E8;&#x529B;&#x91CF;&#xFF0C;(2) &#x7684;&#x5206;&#x5E03;&#x65B9;&#x5F0F;&#x4E4B;&#x95F4;&#x7684;&#x7EDD;&#x5BF9;&#x5E73;&#x8861;&#x7684;&#x72B6;&#x6001;&#x548C;&#x529B;&#x91CF;&#x7684;&#x4E0D;&#x5E73;&#x8861;&#x7684;&#x6A21;&#x5F0F;&#x662F;&#x4E0E;&#x4E0D;&#x540C;&#x7684;&#x53E3;&#x8154;&#x529F;&#x80FD;&#x4E0D;&#x540C;&#x3001; (3) &#x4E0B;&#x988C;&#x524D;&#x7259;&#x820C;&#x4FA7;&#x5728;&#x53E3;&#x8154;&#x529F;&#x80FD;&#x671F;&#x95F4;&#x5FCD;&#x53D7;&#x6781;&#x5927;&#x7684;&#x4E0D;&#x540C;&#x548C;&#x5B83;&#x53EF;&#x80FD;&#x5360;&#x5B89;&#x6C0F;&#x5728;&#x6B64;&#x90E8;&#x5206;&#x4E2D;&#x7684;&#x53D1;&#x75C5;&#x7387;&#x9AD8;&#x53CA; (4) &#x808C;&#x8089;&#x529B;&#x91CF;&#x4E0E;&#x6027;&#x522B;&#x7EDF;&#x8BA1;&#x5DEE;&#x5F02;&#x5B58;&#x5728;&#x3002;

&#x65BD;&#x52A0;&#x6B63;&#x5E38;&#x843D;&#x53F6;&#x7259;&#x5217;&#x7684;&#x808C;&#x8089;&#x529B;&#x91CF;&#x3002;

This study evaluated the distributing characteristic of the forces exerting on the normal deciduous dentition and the relationship between the muscular forces, sex, and oral function. The pressure measurements were made with a computer-aided perioral force-measuring system designed by the authors. The forces were measured when the subject's head position was in a state of natural head position and oral function was at rest or with swallowing. The results indicated that the forces from lips, cheeks, and tongue at rest were about 37-208 N/m2, whereas the pressure during swallowing was about 1009-1679 N/m2. At rest, the pressure from lips and cheeks was higher than that from tongue (P < .05), whereas during swallowing, the lingual pressure was statistically larger (P < .001). A significant correlation existed between the muscular pressure and sex. When at rest, the boy's force from cheeks was higher than that of the girl's (P < .05) but during swallowing the boy's labial pressure was statistically higher than that of the girl's (P < .01). It was concluded that (1) the deciduous teeth are not in a state of absolute balance between external and internal forces, (2) the distributing manner and unbalanced mode of the forces are different with the different oral functions, (3) the lingual side of the mandibular anterior teeth endures great differences during oral functions and it may account for high incidence of malocclusion in this segment, and (4) a statistical difference between muscular forces and sex exists.

Muscular forces exerted on the normal deciduous dentition.

Cette &eacute;tude a &eacute;valu&eacute; la distribution caract&eacute;ristique des forces exercent sur la lact&eacute;ale normale et la relation entre les forces musculaires, le sexe et la fonction orale. Les mesures de pression ont &eacute;t&eacute; faites avec un syst&egrave;me de mesure de la force de perioral assist&eacute;e par ordinateur con&ccedil;u par les auteurs. Les forces ont &eacute;t&eacute; mesur&eacute;s lorsque la position de la t&ecirc;te du sujet &eacute;tait dans un &eacute;tat de la position naturelle de la t&ecirc;te et fonction buccale &eacute;tait au repos ou &agrave; avaler. Les r&eacute;sultats ont indiqu&eacute; que les forces de l&egrave;vres, joues et la langue au repos &eacute;taient sur 37-208 N/m2, alors que la pression lors de la d&eacute;glutition est sur 1009-1679 N/m2. Au repos, la pression des l&egrave;vres et des joues &eacute;tait sup&eacute;rieure &agrave; celui de la langue (P &lt;.05), consid&eacute;rant que lors de la d&eacute;glutition, la pression linguale &eacute;tait statistiquement plus importante (P. 001 &lt;. Une corr&eacute;lation significative existe entre la pression musculaire et le sexe. Au repos, la force du gar&ccedil;on de joues &eacute;tait sup&eacute;rieur &agrave; celui de la jeune fille (P &lt;.05) mais lors de la d&eacute;glutition le gar&ccedil;on de pression labiale &eacute;tait statistiquement sup&eacute;rieur &agrave; celui de la jeune fille (P &lt;.01. Il a &eacute;t&eacute; conclu que (1) les dents ne sont pas dans un &eacute;tat d&#39;&eacute;quilibre absolu entre les forces internes et externes, (2) les modalit&eacute;s de distribution et mode asym&eacute;trique des forces sont diff&eacute;rents avec les diff&eacute;rentes fonctions orales, (3) la face linguale des dents mandibulaires ant&eacute;rieurs endure de grandes diff&eacute;rences pendant les fonctions orales et il peut rendre compte de l&#39;incidence &eacute;lev&eacute;e de malocclusion dans ce segmentet (4) il existe une diff&eacute;rence statistique entre les forces musculaires et le sexe.

Forces musculaires exerc&eacute;es sur la lact&eacute;ale normal.

Diese Studie beurteilte das Verteilen von Merkmal der Kr&auml;fte auf das normale Laub-Gebiss und die Beziehung zwischen der muskul&auml;ren Kr&auml;fte, Geschlecht und orale Funktion auszu&uuml;ben. Die Druckmessungen wurden mit einem computergest&uuml;tzten periorale Kraft-Mess-System entwickelt, die von den Autoren gemacht. Die Kr&auml;fte wurden gemessen, wenn das Thema Kopfposition in einem Zustand der nat&uuml;rlichen Kopfposition war und orale Funktion in Ruhe oder mit schlucken. Die Ergebnisse zeigten, dass die Kr&auml;fte von Lippen, Wangen und Zunge in Ruhe &uuml;ber waren 37-208 N/m2, w&auml;hrend der Druck beim Schlucken &uuml;ber war 1009 &ndash; 1679 N/m2. In Ruhe, der Druck der Lippen und Wangen war h&ouml;her als die von Zunge (P &lt;.05 stehen w&auml;hrend der linguale Druck beim Schlucken, statistisch gr&ouml;&szlig;ere war (P &lt;. 001). Eine signifikante Korrelation bestand zwischen den muskul&ouml;sen Druck und Sex. Wenn Sie sich in Ruhe, der junge Kraft aus Wangen war h&ouml;her als der des M&auml;dchens (P &lt;.05) aber w&auml;hrend der junge Schlucken der labial Druck war statistisch h&ouml;her als der des M&auml;dchens (P &lt;.01). Es wurde gefolgert, da&szlig; (1) die Laub-Z&auml;hne nicht in einem Zustand der absoluten Gleichgewicht zwischen &auml;u&szlig;eren und inneren Kr&auml;ften, (2) die Verteilung von Weise sind und unausgeglichene Modus der Kr&auml;fte unterscheiden sich mit den verschiedenen oralen Funktionen, (3) die linguale Seite der vorderen Unterkiefer-Z&auml;hne gro&szlig;e Unterschiede bei oralen Funktionen h&auml;lt und sie sein f&uuml;r die hohe Inzidenz von Malokklusion in diesem Segment verantwortlich k&ouml;nnen, und (4) ein statistischer Unterschied zwischen muskul&auml;ren Kr&auml;fte und Geschlecht vorhanden ist.

Muskul&auml;re Kr&auml;fte auf das normale Laub-Gebiss ausge&uuml;bt.

Questo studio ha valutato la distribuzione caratteristica delle forze esercitare la normale dentizione decidua e il rapporto tra le forze muscolari, sesso e funzione orale. Le misurazioni di pressione sono state realizzate con un sistema di misurazione della forza di computer-aided periorale progettato dagli autori. Le forze sono state misurate quando la posizione di testa del soggetto era in uno stato di naturale posizione di testa e funzione orale era a riposo o con la deglutizione. I risultati hanno indicato che le forze da labbra, guance e lingua a riposo erano circa 37-208 N/m2, mentre la pressione durante la deglutizione era circa 1009-1679 N/m2. A riposo, la pressione da labbra e guance era superiore a quella da lingua (P &lt;,05 dai considerando che durante la deglutizione, la pressione linguale era statisticamente maggiore (P &lt; 001 dentellatura Una significativa correlazione esistente tra la pressione muscolare e sesso. Quando a riposo, forza del ragazzo dalle guance era superiore a quello della ragazza (P &lt;,05) ma durante la deglutizione il ragazzo di pressione labiale era statisticamente superiore a quella della ragazza (P &lt;,01 dentellatura Si &egrave; concluso che (1) i denti decidui non sono in uno stato di assoluto equilibrio tra forze esterne ed interne, (2) le modalit&agrave; di distribuzione e modalit&agrave; sbilanciata delle forze sono differenti con le differenti funzioni orali, (3) il lato linguale dei denti anteriori mandibolari sopporta grandi differenze durante le funzioni orali e pu&ograve; spiegare per alta incidenza di malocclusione in questo segmentoe (4) esiste una differenza statistica tra le forze muscolari e sesso.

Muscolare forze esercitate sulla normale dentizione decidua.

&#x6B63;&#x5E38;&#x4E73;&#x6B6F;&#x5217;&#x671F;&#x3068;&#x7B4B;&#x306E;&#x529B;&#x30FB;&#x6027;&#x5225;&#x30FB;&#x53E3;&#x8154;&#x6A5F;&#x80FD;&#x3068;&#x306E;&#x95A2;&#x4FC2;&#x3092;&#x767A;&#x63EE;&#x529B;&#x306E;&#x5206;&#x914D;&#x7279;&#x6027;&#x306B;&#x3064;&#x3044;&#x3066;&#x691C;&#x8A0E;&#x3057;&#x307E;&#x3059;&#x3002;&#x5727;&#x529B;&#x6E2C;&#x5B9A;&#x306F;&#x8457;&#x8005;&#x306B;&#x3088;&#x3063;&#x3066;&#x4F5C;&#x3089;&#x308C;&#x305F;&#x30B3;&#x30F3;&#x30D4;&#x30E5;&#x30FC;&#x30BF;&#x30FC;&#x63F4;&#x7528;&#x53E3;&#x5507;&#x529B;&#x6E2C;&#x5B9A;&#x30B7;&#x30B9;&#x30C6;&#x30E0;&#x3067;&#x884C;&#x308F;&#x308C;&#x307E;&#x3057;&#x305F;&#x3002;&#x529B;&#x306F;&#x88AB;&#x9A13;&#x8005;&#x306E;&#x982D;&#x306E;&#x4F4D;&#x7F6E;&#x306F;&#x81EA;&#x7136;&#x982D;&#x4F4D;&#x306E;&#x72B6;&#x614B;&#x306B;&#x3042;&#x3063;&#x305F;&#x3057;&#x3001;&#x5B89;&#x9759;&#x6642;&#x3084;&#x56A5;&#x4E0B;&#x306E;&#x53E3;&#x8154;&#x6A5F;&#x80FD;&#x3092;&#x3055;&#x308C;&#x305F;&#x3068;&#x304D;&#x306B;&#x6E2C;&#x5B9A;&#x3057;&#x307E;&#x3057;&#x305F;&#x3002;&#x7D50;&#x679C;&#x3067;&#x306F;&#x5507;&#x3001;&#x982C;&#x3001;&#x304A;&#x3088;&#x3073;&#x5B89;&#x9759;&#x6642;&#x306E;&#x820C;&#x304B;&#x3089;&#x8ECD;&#x306B;&#x3064;&#x3044;&#x3066;&#x793A;&#x3057;&#x305F; 37 208 N/m 2&#x3001;&#x56A5;&#x4E0B;&#x6642;&#x5727;&#x529B;&#x306B;&#x3064;&#x3044;&#x3066;&#x3060;&#x3063;&#x305F;&#x306B;&#x5BFE;&#x3057; 1009&#x5E74;-1679 N/m 2&#x3002;&#x6B8B;&#x308A;&#x306E;&#x90E8;&#x5206;&#x3067;&#x306F;&#x3001;&#x5507;&#x3068;&#x982C;&#x304B;&#x3089;&#x306E;&#x5727;&#x529B;&#x306E;&#x820C;&#x304B;&#x3089;&#x9AD8;&#x304B;&#x3063;&#x305F; &#xFF08;P &lt;.05 &#x4F8B;&#x3048;&#x3070;&#x56A5;&#x4E0B;&#x6642;&#x820C;&#x5727;&#x304C;&#x6709;&#x610F;&#x306B;&#x5927;&#x304D;&#x304F;&#x3060;&#x3063;&#x305F;&#x306B;&#x5BFE;&#x3057; &#xFF08;P &lt;.001&#x3002;&#x6709;&#x610F;&#x306A;&#x76F8;&#x95A2;&#x95A2;&#x4FC2;&#x306B;&#x306F;&#x3001;&#x7B4B;&#x8089;&#x306E;&#x5727;&#x529B;&#x3068;&#x30BB;&#x30C3;&#x30AF;&#x30B9;&#x306E;&#x9593;&#x5B58;&#x5728;&#x3057;&#x3066;&#x3044;&#x305F;&#x3002;&#x5B89;&#x9759;&#x6642;&#x3001;&#x5C11;&#x5E74;&#x306E;&#x529B;&#x982C;&#x304B;&#x3089;&#x5C11;&#x5973;&#x306E;&#x3088;&#x308A;&#x9AD8;&#x3044;&#x3060;&#x3063;&#x305F; (P &lt;.05) &#x304C;&#x3001;&#x5C11;&#x5E74;&#x306E;&#x56A5;&#x4E0B;&#x6642;&#x53E3;&#x5507;&#x5727;&#x3060;&#x3063;&#x305F;&#x306F;&#x5973;&#x5B50;&#x3088;&#x308A;&#x6709;&#x610F;&#x306B;&#x9AD8;&#x304F; (P &lt;.01&#x3002;&#x305D;&#x308C; (1) &#x4E73;&#x6B6F;&#x7D76;&#x5BFE;&#x5916;&#x90E8;&#x3068;&#x5185;&#x90E8;&#x529B;&#x3001;(2) &#x3092;&#x914D;&#x5E03;&#x3059;&#x308B;&#x65B9;&#x6CD5;&#x306E;&#x30D0;&#x30E9;&#x30F3;&#x30B9;&#x306E;&#x72B6;&#x614B;&#x3067;&#x3055;&#x308C;&#x305A;&#x3068;&#x529B;&#x306E;&#x30A2;&#x30F3;&#x30D0;&#x30E9;&#x30F3;&#x30B9; &#x30E2;&#x30FC;&#x30C9;&#x306F;&#x7570;&#x306A;&#x308B;&#x53E3;&#x8154;&#x6A5F;&#x80FD;&#x3092;&#x7570;&#x306A;&#x3063;&#x3066;&#x3001;&#x53E3;&#x8154;&#x6A5F;&#x80FD;&#x306E;&#x9593;&#x306B;&#x5927;&#x304D;&#x306A;&#x9055;&#x3044; (3) &#x4E0B;&#x984E;&#x524D;&#x6B6F;&#x306E;&#x820C;&#x5074;&#x306B;&#x8010;&#x3048;&#x308B;&#x3001;&#x3053;&#x306E;&#x30BB;&#x30B0;&#x30E1;&#x30F3;&#x30C8;&#x306E;&#x4E0D;&#x6B63;&#x54AC;&#x5408;&#x306E;&#x9AD8;&#x3044;&#x767A;&#x751F;&#x7387;&#x3092;&#x8003;&#x616E;&#x53EF;&#x80FD;&#x6027;&#x304C;&#x3042;&#x308B;&#x3053;&#x3068;&#x306B;&#x7DE0;&#x7D50;&#x3055;&#x308C;&#x307E;&#x3057;&#x305F;&#x3002;&#x3001;&#x304A;&#x3088;&#x3073; (4) &#x7B4B;&#x8089;&#x529B;&#x3068;&#x30BB;&#x30C3;&#x30AF;&#x30B9;&#x306E;&#x7D71;&#x8A08;&#x7684;&#x76F8;&#x9055;&#x304C;&#x5B58;&#x5728;&#x3057;&#x307E;&#x3059;&#x3002;

&#x6B63;&#x5E38;&#x4E73;&#x6B6F;&#x5217;&#x671F;&#x3067;&#x7B4B;&#x8089;&#x529B;&#x3002;

&#xC774; &#xC5F0;&#xAD6C;&#xB294; &#xC77C;&#xBC18; &#xB099; &#xC5FD; &#xCE58;&#xC5F4; &#xD558; &#xACE0; &#xADFC;&#xC721; &#xD798;, &#xC139;&#xC2A4;, &#xADF8;&#xB9AC;&#xACE0; &#xAD6C;&#xAC15; &#xAE30;&#xB2A5; &#xAC04;&#xC758; &#xAD00;&#xACC4;&#xC5D0; &#xBC1C;&#xD718; &#xD558;&#xB294; &#xC138;&#xB825;&#xC758; &#xBC30;&#xD3EC; &#xD2B9;&#xC131; &#xD3C9;&#xAC00;. &#xC800;&#xC790;&#xC5D0; &#xC758;&#xD574; &#xC124;&#xACC4; &#xB41C; &#xC804;&#xC0B0; perioral &#xD798; &#xCE21;&#xC815; &#xC2DC;&#xC2A4;&#xD15C; &#xC555;&#xB825; &#xCE21;&#xC815; &#xB418;&#xC5C8;&#xB2E4;. &#xAD70;&#xB300; &#xB54C; &#xD53C;&#xC0AC;&#xCCB4;&#xC758; &#xBA38;&#xB9AC; &#xC704;&#xCE58; &#xC790;&#xC5F0; &#xBA38;&#xB9AC; &#xC704;&#xCE58; &#xC0C1;&#xD0DC;&#xC5D0; &#xC788;&#xC5C8;&#xACE0; &#xAD6C;&#xAC15; &#xD568;&#xC218;&#xB294; &#xD734;&#xC2DD; &#xB610;&#xB294; &#xC0BC; &#xD0A4;&#xB294; &#xD568;&#xAED8; &#xCE21;&#xC815; &#xD588;&#xB2E4;. &#xACB0;&#xACFC; &#xD45C;&#xC2DC;, &#xC785;&#xC220;, &#xBEA8;, &#xADF8;&#xB9AC;&#xACE0; &#xB098;&#xBA38;&#xC9C0;&#xC5D0; &#xD600;&#xC5D0;&#xC11C; &#xAD70;&#xB300;&#xC5D0; &#xB300; &#xD55C; &#xD588;&#xB2E4; 37-208 N/m2, &#xC0BC; &#xD0A4;&#xB294; &#xB3D9;&#xC548; &#xC555;&#xB825;&#xC5D0; &#xB300; &#xD55C; &#xBC18;&#xBA74; 1009-1679 N/m2. &#xD734;&#xC2DD;&#xC744;, &#xC785;&#xC220;&#xACFC; &#xBEA8;&#xC5D0;&#xC11C; &#xC555;&#xB825; &#xD600;&#xC5D0;&#xC11C; &#xBCF4;&#xB2E4; &#xB192;&#xC558;&#xB2E4; (P &lt;.05), &#xC0BC; &#xD0A4;&#xB294; &#xB3D9;&#xC548; &#xC5B8;&#xC5B4; &#xC555;&#xB825;&#xC740; &#xD1B5;&#xACC4;&#xC801;&#xC73C;&#xB85C; &#xB354; &#xD070; &#xBC18;&#xBA74; (P &lt; 001. &#xC911;&#xC694; &#xD55C; &#xC0C1;&#xAD00; &#xAD00;&#xACC4; &#xADFC;&#xC721; &#xC9C8;&#xC758; &#xC555;&#xB825;&#xACFC; &#xC139;&#xC2A4; &#xC0AC;&#xC774; &#xC874;&#xC7AC; &#xD569;&#xB2C8;&#xB2E4;. &#xD734;&#xC2DD;&#xC744;, &#xBEA8;&#xC5D0;&#xC11C; &#xC18C;&#xB144;&#xC758; &#xD798;&#xC758; &#xC5EC;&#xC790;&#xC758; &#xADF8;&#xAC83; &#xBCF4;&#xB2E4; &#xB192;&#xC558;&#xB2E4; (P &lt;.05) &#xD558;&#xC9C0;&#xB9CC; &#xC18C;&#xB144;&#xC744; &#xC0BC; &#xD0A4;&#xB294; &#xB3D9;&#xC548;&#xC758; &#xC785;&#xC220; &#xC555;&#xB825;&#xC740; &#xD1B5;&#xACC4;&#xC801;&#xC73C;&#xB85C; &#xADF8; &#xC5EC;&#xC790;&#xC758; &#xBCF4;&#xB2E4; &#xB192;&#xC740; (P &lt;.01. &#xADF8;&#xAC83;&#xC740; (1) &#xB099; &#xC5FD; &#xCE58;&#xC544; &#xC678;&#xBD80; &#xBC0F; &#xB0B4;&#xBD80; &#xC138;&#xB825; (2) &#xBC30;&#xD3EC; &#xBC29;&#xBC95; &#xAC04;&#xC758; &#xC808;&#xB300; &#xADE0;&#xD615;&#xC758; &#xC0C1;&#xD0DC;&#xC5D0; &#xC788;&#xC9C0; &#xC54A;&#xC740;, &#xD798;&#xC758; &#xBD88;&#xADE0;&#xD615;&#xB41C; &#xBAA8;&#xB4DC;&#xB294; &#xB2E4;&#xB978; &#xAD6C;&#xAC15; &#xAE30;&#xB2A5;&#xC744; &#xAC00;&#xC9C4; &#xB2E4;&#xB978;, (3) &#xC5B8;&#xC5B4;&#xC801; &#xCE21;&#xBA74; mandibular &#xC55E;&#xCABD; &#xCE58;&#xC544;&#xC758; &#xAD6C;&#xAC15; &#xAE30;&#xB2A5; &#xD558;&#xB294; &#xB3D9;&#xC548; &#xD070; &#xCC28;&#xC774; &#xC601; &#xC18D;&#xC744; malocclusion&#xC774;&#xC774; &#xBD84;&#xC57C;&#xC5D0;&#xC11C;&#xC758; &#xB192;&#xC740; &#xBC1C;&#xBCD1; &#xB960;&#xC5D0; &#xB300; &#xD55C; &#xACC4;&#xC815; &#xC218; &#xC788;&#xC2B5;&#xB2C8;&#xB2E4; &#xCCB4;&#xACB0; &#xD588;&#xB2E4;&#xADF8;&#xB9AC;&#xACE0; (4) &#xADFC;&#xC721; &#xC138;&#xB825;&#xACFC; &#xC139;&#xC2A4;&#xC758; &#xD1B5;&#xACC4;&#xC801; &#xCC28;&#xC774; &#xC874;&#xC7AC;.

&#xADFC;&#xC721; &#xD798;&#xC740; &#xC77C;&#xBC18; &#xB099; &#xC5FD; &#xCE58;&#xC5F4;&#xC5D0;&#xAC00; &#xD574;&#xC9C0;&#xC785;&#xB2C8;&#xB2E4;.

Este estudio evalu&oacute; la caracter&iacute;stica distribuci&oacute;n de las fuerzas ejerciendo en la dentici&oacute;n normal y la relaci&oacute;n entre las fuerzas musculares, sexo y funci&oacute;n oral. Se realizaron las mediciones de presi&oacute;n con un sistema de medici&oacute;n de fuerza perioral asistido por ordenador, dise&ntilde;ado por los autores. Se midieron las fuerzas cuando la posici&oacute;n de la cabeza del sujeto se encontraba en un estado de posici&oacute;n natural de la cabeza y funci&oacute;n oral estaba en reposo o con la degluci&oacute;n. Los resultados indicaron que las fuerzas de labios, mejillas y lengua en reposo fueron sobre 37-208 N/m2, mientras que la presi&oacute;n al tragar trataba 1009-1679 N/m2. En reposo, la presi&oacute;n de los labios y las mejillas fue mayor que el de la lengua (P.05 &lt;), Considerando que durante la degluci&oacute;n, la presi&oacute;n lingual fue estad&iacute;sticamente mayor (P &lt;. 001. Una correlaci&oacute;n significativa existi&oacute; entre la presi&oacute;n muscular y el sexo. Cuando est&aacute; en reposo, fuerza del ni&ntilde;o de mejillas fue mayor que el de la ni&ntilde;a (P &lt;.05) pero al tragar el muchacho de presi&oacute;n labial fue estad&iacute;sticamente mayor que el de la ni&ntilde;a (P &lt;.01. Se concluy&oacute; que (1) los dientes deciduos no est&aacute;n en un estado de absoluto equilibrio entre fuerzas internas y externas, (2) la forma de distribuci&oacute;n y modo de desequilibrio de las fuerzas son diferentes con las diferentes funciones orales, (3) el lado lingual de los dientes de la mand&iacute;bula anteriores aguanta grandes diferencias durante las funciones orales y puede explicar por la alta incidencia de maloclusi&oacute;n en este segmentoy (4) existe una diferencia estad&iacute;stica entre las fuerzas musculares y el sexo.

Fuerzas musculares ejercidas sobre la dentici&oacute;n normal.

The methods to determine the parameters of a one-dimensional compression model for landfilled municipal solid waste were investigated. In order to test the methods for parameter determination, long-term laboratory compression experiments were carried out under different surcharge loads (i.e. 100, 200 and 400 kPa). Based on the measured compression strain and the reported creep index, the modified primary compression indexes, pre-consolidation pressure and ultimate biodegradation-induced secondary compression strain were determined using the proposed methods. It was found that the simulated compression could not capture the measured secondary compression behavior when using a constant value of biodegradation-induced compression rate coefficient. The variation of the rate coefficient with the change of decomposition rate should be considered during modeling. Accordingly, the biodegradation-induced secondary compression strain in the compression model should be expressed in an incremental form in order to consider the variation of the rate coefficient. 

Parameter determination of a compression model for landfilled municipal solid waste: an experimental study.

Recently, candidate genetic studies revealed the single nucleotide polymorphisms (SNPs) of CUGBP2 (rs2242451) and DNMBP (rs11190305 and rs3740058) associated with Alzheimer's disease (AD). Due to genetic heterogeneity and different ethnic background, the purpose of our study was to confirm the association between these 3 SNPs with AD risk in the Chinese Han population.

Genetic association of CUGBP2 and DNMBP with Alzheimer' s disease in the Chinese Han population.

The effect of time from diagnosis to treatment (TDT) on overall survival of patients with acute myeloid leukemia (AML) remains obscure. Furthermore, whether chemotherapy delay impacts overall survival (OS) of patients with a special molecular subtype has not been investigated. Here, we enrolled 364 cases of AML to assess the effect of TDT on OS by fractional polynomial regression in the context of clinical parameters and genes of FLT3ITD, NPM1, CEBPA, DNMT3a, and IDH1/2 mutations. Results of the current study show IDH1/2 mutations are associated with older age, M0 morphology, an intermediate cytogenetic risk group, and NPM1 mutations. TDT associates with OS for AML patients in a nonlinear pattern with a J shape. Moreover, adverse effect of delayed treatment on OS was observed in patients with IDH1/2 mutations, but not in those with IDH1/2 wildtype. Therefore, initiating chemotherapy as soon as possible after diagnosis might be a potential strategy to improve OS in AML patients with IDH1/2 mutations. 

Impact of Chemotherapy Delay on Overall Survival for AML with IDH1/2 Mutations: A Study in Adult Chinese Patients.

Begomoviruses are transmitted by cryptic species of the whitefly Bemisia tabaci complex, often in a species-specific manner. Papaya leaf curl China virus (PaLCuCNV) has been recorded to infect several crops including papaya, tomato and tobacco in China. To help assess the risks of spread of this virus, we compared the acquisition, retention and transmission of PaLCuCNV among four species of whiteflies, Middle East-Asia Minor 1 (MEAM1), Mediterranean (MED), Asia 1 and Asia II 7. All four species of whiteflies are able to acquire, retain and transmit the virus, but with different levels of efficiency. Transmission tests using tomato as the host plant showed that MEAM1 transmitted PaLCuCNV with substantially higher efficiency than did MED, Asia 1 and Asia II 7. Furthermore, accumulation of PaLCuCNV in the whiteflies was positively associated with its efficiency of transmitting the virus. Altogether, these findings indicate that MEAM1 is the most efficient vector for PaLCuCNV in the four species of whiteflies, and suggest that risks of PaLCuCNV pandemics are high in regions where MEAM1 occurs.

Comparison of transmission of Papaya leaf curl China virus among four cryptic species of the whitefly Bemisia tabaci complex.

Huntingtin interacting protein 1 (HIP1) is an endocytic protein which is overexpressed in a variety of human cancers and involved in cancer-causing translocation in leukemia. However, the prognostic impact of HIP1 expression on AML remains unclear. In this study, quantification of HIP1 transcript by real-time quantitative PCR in bone marrow blasts was performed in 270 AML patients. As a result, high HIP1 expression was seen more frequently in older patients, M4/M5 morphology and genes of NPM1 and DNMT3A mutations, and underrepresented in favorable karyotype subgroups and CEBPA double allele mutations in our AML patients. We also found high HIP1 expressers showed lower levels of hemoglobin. In addition, overexpression of HIP1 was associated with an inferior overall survival. The prognostic value of HIP1 expression was validated in patients from an independent TCGA cohort. Notably, up-regulation of miR-16, miR-15a, miR-28 and miR-660 were seen in high HIP1 expressers from the two independent cohorts. In vitro, interfereing of HIP1 expression by siRNA suppressed the proliferation of leukemic cells, and downregulation of these miRNAs were seen in THP-1 and Kasumi cell lines after silencing HIP1 expression. In conclusion, the HIP1 gene expression might serve as a reliable predictor for overall survival in AML patients.

Prognostic significance of huntingtin interacting protein 1 expression on patients with acute myeloid leukemia.

The majority of plant viruses are transmitted by insect vectors between hosts, and transovarial transmission of viruses from vector parents to offspring has great significance to their epidemiology. Begomoviruses are transmitted by the whitefly Bemisia tabaci in a circulative manner and are maintained through a plant-insect-plant cycle. Other routes of begomovirus transmission are not clearly known. Here, we report that transovarial transmission from female whiteflies to offspring often happens for one begomovirus, Tomato yellow leaf curl virus (TYLCV), and may have contributed significantly to its global spread. We found that TYLCV entry of the reproductive organ of its vector mainly depended on the developmental stage of the whitefly ovary, and the transovarial transmission of TYLCV to offspring increased with whitefly adult age. The specific interaction between virus coat protein (CP) and whitefly vitellogenin (Vg) was vital for virus entry into whitefly ovary. When knocking down the expression of Vg, the entry of TYLCV into ovary was inhibited and the transovarial transmission efficiency decreased. In contrast, another begomovirus, Papaya leaf curl China virus (PaLCuCNV), CP did not interact with whitefly Vg, and PaLCuCNV could not be transovarially transmitted by whiteflies. We further showed that TYLCV could be maintained for at least two generations in the absence of virus-infected plants, and the adult progenies were able to infect healthy plants in both the laboratory and field. This study reports the transovarial transmission mechanism of begomoviruses, and it may help to explain the evolution and global spread of some begomoviruses.

Vector development and vitellogenin determine the transovarial transmission of begomoviruses.

Approximately 50% of older patients with acute myeloid leukemia (AML) do not obtain chromosomal abnormalities as an effective risk-stratification, and present cytogenetically normal AML (CN-AML). To develop a reliable prediction model for stratifying the risk of these elderly patients, we conducted a study with a discovery and validation design. As a result, we found the top 6 mutated genes in the discovery cohort of 26 case by the whole exome sequencing, and verified as recurrent mutations in the large cohort of 329 patients by Sanger sequencing. The top 6 genes were NPM1, FLT3-ITD, DNMT3A, CEBPA double allele, IDH1 and IDH2 mutations, and the frequency of each gene in the combining cohort was 36.8%, 19.8%, 20.1%, 5.8%, 14.9% and 22.5%, respectively. In addition, clinical variables such as age, white blood cell counts, genes of IDH1 and DNMT3A mutations, European LeukemiaNet genotype (NPM1 mutations and lacking FLT3-ITD or CEBPA double allele mutations) and treatment protocols were independent factors for predicting the probabilities of overall and event-free survival. The prediction nomograms based on these significant factors showed accurate discrimination. In conclusion, we developed a reliable prediction model for stratifying the risk of elderly patients with CN-AML.

Prognostic utility of six mutated genes for older patients with acute myeloid leukemia.

Acute kidney injury (AKI) is associated with the increased short-term mortality of critically ill patients on continuous renal replacement therapy (CRRT). The aim of this research was to evaluate the association of kidney function at discharge with the long-term renal and overall survival of critically ill patients with AKI who were on CRRT in an intensive care unit (ICU).

Long-term renal and overall survival of critically ill patients with acute renal injury who received continuous renal replacement therapy.

Ten-Eleven-Translocation 1 (TET1) plays a role in the DNA methylation process and gene activation. Recent reports suggest TET1 acts as an oncogene in leukemia development. However, the clinical relevance and biological insight of TET1 expression in cytogenetically normal acute myeloid leukemia (CN-AML) is unknown. In this study, quantification of TET1 transcript by real-time quantitative PCR in bone marrow blasts was performed in 360 CN-AML patients. As a result, high TET1 expression was more common in M0/M1 morphology and genes of NPM1 mutations, and underrepresented in CEBPA double allele mutations in our AML patients. In addition, we found overexpression of TET1 was associated with an inferior overall survival and event free survival in the two independent cohorts. Notably, mRNA and miRNA integrative analyses showed aberrant expression of several hub oncogenes appear to be regulated by some miRNAs like miR-127-5p, miR-494, miR-21 and miR-616 in high TET1 expressers. In conclusion, the TET1 gene expression might serve as a reliable predictor for patients survival in AML.

High Expression of TET1 Predicts Poor Survival in Cytogenetically Normal Acute Myeloid Leukemia From Two Cohorts.

The prognostic value of geriatric nutritional risk index (GNRI) for diffuse large B-cell lymphoma (DLBCL) treated in the rituximab era was not clear.

Geriatric nutritional risk index is not an independent predictor in patients with diffuse large B-cell lymphoma.

To analyze the clinical characteristics and prognostic value of prognostic nutritional index (PNI) for diffuse large B-cell lymphoma (DLBCL) treated in the rituximab era, baseline clinical and disease characteristics were recorded in our hospital. Concentration of T-helper cell type (Th1/Th2/Th17) cytokine profiles were measured by flow cytometry. DLBCL patients were classified into low and high PNI group based on the cutoff value as previously reported. Clinical features and survivals were compared between high and low group. In all, 114 (37%) out of 309 patients were classified as low PNI group. The low group had lower levels of albumin, hemoglobin and lymphocyte counts, and older age, and high lactate dehydroxygenase (LDH), and high frequencies of advanced stage, poor performance status, B symptoms, extranodal involvement, and higher level of interferon gamma (INF-γ). Low PNI was associated with poor overall survival (OS) in univariate analyses. But these significances did not stand in the paired patients matched by the well-established prognostic factors. In parallel, there was no significance between survival and PNI in the multivariate analyses. PNI was closely correlated with the well-established prognostic factors for DLBCL patients and was not an independent prognostic factor in our study.

Clinical Significance of Prognostic Nutritional Index for Patients with Diffuse Large B-cell Lymphoma.

Begomoviruses contain some of the most damaging viral disease agents of crops worldwide, and are transmitted by whiteflies of the Bemisia tabaci species complex. During the last 20 years, transovarial transmission of tomato yellow leaf curl virus (TYLCV) has been reported in two invasive species of the B. tabaci complex. To further decipher the importance of this mode of transmission, we analyzed transovarial transmission of TYLCV by seven whitefly species indigenous to China. TYLCV virions were detected in eggs of all species except one, and in nymphs of two species, but in none of the ensuing adults of all seven species. Our results suggest that these indigenous whiteflies are unable to transmit TYLCV, a begomovirus alien to China, via ova to produce future generations of viruliferous adults, although most of the species exhibit varying ability to carry over the virus to the eggs/nymphs of their offspring via transovarial transmission.

Transovarial transmission of tomato yellow leaf curl virus by seven species of the Bemisia tabaci complex indigenous to China: Not all whiteflies are the same.

Aberrant metabolism is a hallmark of cancer cells. Recently, ATP citrate-lyase (ACLY) expression was demonstrated as an independent predictor of clinical outcome in solid tumors. However, no systematic study was conducted to explore the prognostic impact of ACLY on acute myeloid leukemia (AML).

Low expression of ACLY associates with favorable prognosis in acute myeloid leukemia.

In wet magnesia desulfurization, the ultrahigh stable catalysis of sulfite oxidation is a crucial step in byproduct reclaimation. In this study, a robust and efficient catalyst, Co-MOF-74(4), was synthesized through a facile solvothermal method with an optimal Co/ligand ratio of 4:1. The oxidation rate of magnesium sulfite catalyzed by Co-MOF-74(4) was >2.6 times higher than that of previously reported cobalt-based heterogeneous catalysts. Crucially, almost no attenuation of the catalytic activity was observed even after three reuse cycles. The properties of Co-MOF-74(4) before and after the reaction were characterized. Density functional theory calculations demonstrate that the unsaturated cobalt site on the open framework of Co-MOF-74(4) provides greater opportunity for active Co to be attacked by sulfite ions, resulting in the ultra-high catalytic activity of Co-MOF-74(4). In contrast to the conventional impregnated catalysts, the robust combination of active cobalt with ligands prohibits its stripping from the surface of Co-MOF-74(4) particles. The bond length, angle and lattice parameters have only slight changes after sulfite adsorption, which supports the stability of the catalyst in the reaction process.

Article	Year
[Study of muscle pressure exerted on deciduous normal occlusion]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences\| PubMed ID: 15269988	2004
Muscular forces exerted on the normal deciduous dentition. The Angle orthodontist\| PubMed ID: 16279824	2005
Parameter determination of a compression model for landfilled municipal solid waste: an experimental study. Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA\| PubMed ID: 25649408	2015
Genetic association of CUGBP2 and DNMBP with Alzheimer' s disease in the Chinese Han population. Current Alzheimer research\| PubMed ID: 25801238	2015
Impact of Chemotherapy Delay on Overall Survival for AML with IDH1/2 Mutations: A Study in Adult Chinese Patients. PloS one\| PubMed ID: 26466372	2015
Comparison of transmission of Papaya leaf curl China virus among four cryptic species of the whitefly Bemisia tabaci complex. Scientific reports\| PubMed ID: 26486606	2015
Prognostic significance of huntingtin interacting protein 1 expression on patients with acute myeloid leukemia. Scientific reports\| PubMed ID: 28452374	2017
Vector development and vitellogenin determine the transovarial transmission of begomoviruses. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28607073	2017
Prognostic utility of six mutated genes for older patients with acute myeloid leukemia. International journal of cancer\| PubMed ID: 29193057	2018
Long-term renal and overall survival of critically ill patients with acute renal injury who received continuous renal replacement therapy. Renal failure\| PubMed ID: 29199512	2017
High Expression of TET1 Predicts Poor Survival in Cytogenetically Normal Acute Myeloid Leukemia From Two Cohorts. EBioMedicine\| PubMed ID: 29402726	2018
Geriatric nutritional risk index is not an independent predictor in patients with diffuse large B-cell lymphoma. Cancer biomarkers : section A of Disease markers\| PubMed ID: 29504524	2018
Clinical Significance of Prognostic Nutritional Index for Patients with Diffuse Large B-cell Lymphoma. Nutrition and cancer\| PubMed ID: 30596268	2019
Transovarial transmission of tomato yellow leaf curl virus by seven species of the Bemisia tabaci complex indigenous to China: Not all whiteflies are the same. Virology\| PubMed ID: 30933715	2019
Low expression of ACLY associates with favorable prognosis in acute myeloid leukemia. Journal of translational medicine\| PubMed ID: 31077215	2019
Cobalt-based metal-organic frameworks promoting magnesium sulfite oxidation with ultrahigh catalytic activity and stability. Journal of colloid and interface science\| PubMed ID: 31610308	2020

Qi Guo

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