Department of Medicine/Heart and Vascular Institute,
Department of Physiology,
Department of Pharmacology
Patrice Delafontaine has not added Biography.
If you are Patrice Delafontaine and would like to personalize this page please email our Author Liaison for assistance.
Insulin-like growth factor-1 receptor activation inhibits oxidized LDL-induced cytochrome C release and apoptosis via the phosphatidylinositol 3 kinase/Akt signaling pathway.
Arteriosclerosis, thrombosis, and vascular biology Dec, 2003 | Pubmed ID: 14551153
Expression, regulation, and function of IGF-1, IGF-1R, and IGF-1 binding proteins in blood vessels.
Arteriosclerosis, thrombosis, and vascular biology Mar, 2004 | Pubmed ID: 14604834
Technique and imaging for transthoracic echocardiography of the laboratory pig.
Echocardiography (Mount Kisco, N.Y.) Jul, 2004 | Pubmed ID: 15209726
Endothelial dysfunction: its role in hypertensive coronary disease.
Current opinion in cardiology Jul, 2005 | Pubmed ID: 15956822
Angiotensin II stimulates transcription of insulin-like growth factor I receptor in vascular smooth muscle cells: role of nuclear factor-kappaB.
Endocrinology Mar, 2006 | Pubmed ID: 16322063
Angiotensin II as candidate of cardiac cachexia.
Current opinion in clinical nutrition and metabolic care May, 2006 | Pubmed ID: 16607120
Predictors of left ventricular dilatation in young adults (from the Bogalusa Heart Study).
The American journal of cardiology Nov, 2006 | Pubmed ID: 17056336
Enhancing repair of the mammalian heart.
Circulation research Jun, 2007 | Pubmed ID: 17525368
The ubiquitin ligase Nedd4 mediates oxidized low-density lipoprotein-induced downregulation of insulin-like growth factor-1 receptor.
American journal of physiology. Heart and circulatory physiology Oct, 2008 | Pubmed ID: 18723765
IL-6 and serum amyloid A synergy mediates angiotensin II-induced muscle wasting.
Journal of the American Society of Nephrology : JASN Mar, 2009 | Pubmed ID: 19158350
Calcific constrictive pericarditis with refractory hypokalemia in a patient with Gitelman's syndrome.
The American journal of the medical sciences Jan, 2009 | Pubmed ID: 19263512
Insulin glargine reduces carotid intimal hyperplasia after balloon catheter injury in Zucker fatty rats possibly by reduction in oxidative stress.
Molecular and cellular biochemistry Oct, 2009 | Pubmed ID: 19360379
Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6.
Cell stem cell Jul, 2009 | Pubmed ID: 19570514
Effect of Hurricane Katrina on the incidence of acute coronary syndrome at a primary angioplasty center in New Orleans.
Disaster medicine and public health preparedness Oct, 2009 | Pubmed ID: 19713855
Growth hormone-releasing peptide-2 suppresses vascular oxidative stress in ApoE-/- mice but does not reduce atherosclerosis.
Endocrinology Dec, 2009 | Pubmed ID: 19819949
IGF-1, oxidative stress and atheroprotection.
Trends in endocrinology and metabolism: TEM Apr, 2010 | Pubmed ID: 20071192
WNT1-inducible signaling pathway protein-1 activates diverse cell survival pathways and blocks doxorubicin-induced cardiomyocyte death.
Cellular signalling May, 2010 | Pubmed ID: 20074638
Vitamin C and percutaneous coronary intervention.
JACC. Cardiovascular interventions Feb, 2010 | Pubmed ID: 20170882
IGF-1 prevents ANG II-induced skeletal muscle atrophy via Akt- and Foxo-dependent inhibition of the ubiquitin ligase atrogin-1 expression.
American journal of physiology. Heart and circulatory physiology May, 2010 | Pubmed ID: 20228261
EMMPRIN activates multiple transcription factors in cardiomyocytes, and induces interleukin-18 expression via Rac1-dependent PI3K/Akt/IKK/NF-kappaB andMKK7/JNK/AP-1 signaling.
Journal of molecular and cellular cardiology Oct, 2010 | Pubmed ID: 20538003
Smooth muscle cell-specific insulin-like growth factor-1 overexpression in Apoe-/- mice does not alter atherosclerotic plaque burden but increases features of plaque stability.
Arteriosclerosis, thrombosis, and vascular biology Oct, 2010 | Pubmed ID: 20671230
Interleukin-18 induces EMMPRIN expression in primary cardiomyocytes via JNK/Sp1 signaling and MMP-9 in part via EMMPRIN and through AP-1 and NF-kappaB activation.
American journal of physiology. Heart and circulatory physiology Oct, 2010 | Pubmed ID: 20693392
Thiazolidinediones up-regulate insulin-like growth factor-1 receptor via a peroxisome proliferator-activated receptor gamma-independent pathway.
The Journal of biological chemistry Nov, 2010 | Pubmed ID: 20843793
Symptoms characteristic of heart failure among CKD patients without diagnosed heart failure.
Journal of cardiac failure Jan, 2011 | Pubmed ID: 21187260
The effect of nebivolol versus metoprolol succinate extended release on asymmetric dimethylarginine in hypertension.
Journal of the American Society of Hypertension : JASH May-Jun, 2011 | Pubmed ID: 21251896
Interleukin-18/WNT1-inducible signaling pathway protein-1 signaling mediates human saphenous vein smooth muscle cell proliferation.
Journal of cellular physiology Dec, 2011 | Pubmed ID: 21321938
Low circulating insulin-like growth factor I increases atherosclerosis in ApoE-deficient mice.
American journal of physiology. Heart and circulatory physiology May, 2011 | Pubmed ID: 21335474
Angiotensin-II type 1 receptor and NOX2 mediate TCF/LEF and CREB dependent WISP1 induction and cardiomyocyte hypertrophy.
Journal of molecular and cellular cardiology Jun, 2011 | Pubmed ID: 21376054
Angiotensin II induced catabolic effect and muscle atrophy are redox dependent.
Biochemical and biophysical research communications Jun, 2011 | Pubmed ID: 21570954
Angiotensin II, oxidative stress and skeletal muscle wasting.
The American journal of the medical sciences Aug, 2011 | Pubmed ID: 21747283
Angiotensin II upregulates protein phosphatase 2Cα and inhibits AMP-activated protein kinase signaling and energy balance leading to skeletal muscle wasting.
Hypertension (Dallas, Tex. : 1979) Oct, 2011 | Pubmed ID: 21844485
β2 adrenergic activation induces the expression of IL-18 binding protein, a potent inhibitor of isoproterenol induced cardiomyocyte hypertrophy in vitro and myocardial hypertrophy in vivo.
Journal of molecular and cellular cardiology Jan, 2012 | Pubmed ID: 22004899
Interleukin-17A stimulates cardiac fibroblast proliferation and migration via negative regulation of the dual-specificity phosphatase MKP-1/DUSP-1.
Cellular signalling Feb, 2012 | Pubmed ID: 22037550
Effect of Hurricane Katrina on incidence of acute myocardial infarction in New Orleans three years after the storm.
The American journal of cardiology Feb, 2012 | Pubmed ID: 22154089
Angiotensin II reduces food intake by altering orexigenic neuropeptide expression in the mouse hypothalamus.
Endocrinology Mar, 2012 | Pubmed ID: 22234465
Angiotensin II infusion induces marked diaphragmatic skeletal muscle atrophy.
PloS one , 2012 | Pubmed ID: 22276172
Aging, atherosclerosis, and IGF-1.
The journals of gerontology. Series A, Biological sciences and medical sciences Jun, 2012 | Pubmed ID: 22491965
Angiotensin II enhances AT1-Nox1 binding and stimulates arterial smooth muscle cell migration and proliferation through AT1, Nox1, and interleukin-18.
American journal of physiology. Heart and circulatory physiology Aug, 2012 | Pubmed ID: 22636674
Skeletal muscle molecular alterations precede whole-muscle dysfunction in NYHA Class II heart failure patients.
Clinical interventions in aging , 2012 | Pubmed ID: 23204842
Insulin-like growth factor-1 regulates glutathione peroxidase expression and activity in vascular endothelial cells: Implications for atheroprotective actions of insulin-like growth factor-1.
Biochimica et biophysica acta Mar, 2013 | Pubmed ID: 23261989
Effect of Hurricane Katrina on chronobiology at onset of acute myocardial infarction during the subsequent three years.
The American journal of cardiology Mar, 2013 | Pubmed ID: 23291089
Advanced oxidation protein products induce cardiomyocyte death via Nox2/Rac1/superoxide-dependent TRAF3IP2/JNK signaling.
Free radical biology & medicine Jul, 2013 | Pubmed ID: 23453926
Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2-dependent smooth muscle cell migration. Inhibition by simvastatin.
Cellular signalling Jun, 2013 | Pubmed ID: 23541442
Persistent giant U wave inversion with anoxic brain injury.
Proceedings (Baylor University. Medical Center) Apr, 2013 | Pubmed ID: 23543982
Preoperative electrocardiogram in an 89-year-old man.
The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society Jan-Feb, 2013 | Pubmed ID: 23550392
Mammographically detectable breast arterial calcification and atherosclerosis.
Cardiology in review Mar-Apr, 2014 | Pubmed ID: 23584424
The therapeutic potential of IGF-I in skeletal muscle repair.
Trends in endocrinology and metabolism: TEM Jun, 2013 | Pubmed ID: 23628587
Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: potential therapeutic targets for cardiac cachexia.
The international journal of biochemistry & cell biology Oct, 2013 | Pubmed ID: 23769949
Coronary angiographic significance of hyperacute ST-T changes associated with regadenoson stress.
Proceedings (Baylor University. Medical Center) Jul, 2013 | Pubmed ID: 23814390
Angiotensin II inhibits satellite cell proliferation and prevents skeletal muscle regeneration.
The Journal of biological chemistry Aug, 2013 | Pubmed ID: 23831688
Acetylsalicylic acid inhibits IL-18-induced cardiac fibroblast migration through the induction of RECK.
Journal of cellular physiology Jul, 2014 | Pubmed ID: 24265116
Docosahexaenoic acid reverses angiotensin II-induced RECK suppression and cardiac fibroblast migration.
Cellular signalling May, 2014 | Pubmed ID: 24447911
Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNA.
The Journal of biological chemistry Mar, 2014 | Pubmed ID: 24469459
Natural disasters and myocardial infarction: the six years after Hurricane Katrina.
Mayo Clinic proceedings Apr, 2014 | Pubmed ID: 24656058
Interaction between insulin-like growth factor-1 and atherosclerosis and vascular aging.
Frontiers of hormone research , 2014 | Pubmed ID: 24943302
Endovascular stent-graft repair of ascending aortic dissection with a commercially available thoracic endograft.
The Annals of thoracic surgery Aug, 2014 | Pubmed ID: 25087800
Pressure overload induces IL-18 and IL-18R expression, but markedly suppresses IL-18BP expression in a rabbit model. IL-18 potentiates TNF-α-induced cardiomyocyte death.
Journal of molecular and cellular cardiology Oct, 2014 | Pubmed ID: 25108227
Angiotensin type 2 receptor signaling in satellite cells potentiates skeletal muscle regeneration.
The Journal of biological chemistry Sep, 2014 | Pubmed ID: 25112871
Digital plethysmography and arginine metabolism in prehypertension: effect of nebivolol therapy.
Journal of clinical hypertension (Greenwich, Conn.) Jan, 2015 | Pubmed ID: 25495953
Insulin-like growth factor I reduces lipid oxidation and foam cell formation via downregulation of 12/15-lipoxygenase.
Atherosclerosis Feb, 2015 | Pubmed ID: 25549319
Protein phosphatase 2C-alpha knockdown reduces angiotensin II-mediated skeletal muscle wasting via restoration of mitochondrial recycling and function.
Skeletal muscle , 2014 | Pubmed ID: 25625009
Elevation of cardiovascular risk by non-steroidal anti-inflammatory drugs.
Trends in cardiovascular medicine Nov, 2015 | Pubmed ID: 25956433
Kansas City Cardiomyopathy Questionnaire Score Is Associated With Incident Heart Failure Hospitalization in Patients With Chronic Kidney Disease Without Previously Diagnosed Heart Failure: Chronic Renal Insufficiency Cohort Study.
Circulation. Heart failure Jul, 2015 | Pubmed ID: 25985796
The Nox1/4 Dual Inhibitor GKT137831 or Nox4 Knockdown Inhibits Angiotensin-II-Induced Adult Mouse Cardiac Fibroblast Proliferation and Migration. AT1 Physically Associates With Nox4.
Journal of cellular physiology May, 2016 | Pubmed ID: 26445208
TRAF3IP2 mediates aldosterone/salt-induced cardiac hypertrophy and fibrosis.
Molecular and cellular endocrinology 07, 2016 | Pubmed ID: 27040306
Insulin-Like Growth Factor-1 Receptor Deficiency in Macrophages Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Apolipoprotein E-Deficient Mice.
Circulation Jun, 2016 | Pubmed ID: 27154724
Sodium Excretion and the Risk of Cardiovascular Disease in Patients With Chronic Kidney Disease.
JAMA May 24-31, 2016 | Pubmed ID: 27218629
TRAF3IP2 mediates atherosclerotic plaque development and vulnerability in ApoE(-/-) mice.
Atherosclerosis 09, 2016 | Pubmed ID: 27237075
Rapid estrogen receptor-α signaling mediated by ERK activation regulates vascular tone in male and ovary-intact female mice.
American journal of physiology. Heart and circulatory physiology 02, 2018 | Pubmed ID: 28887333
SM22α (Smooth Muscle Protein 22-α) Promoter-Driven IGF1R (Insulin-Like Growth Factor 1 Receptor) Deficiency Promotes Atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 10, 2018 | Pubmed ID: 30354209
ABOUT JoVE
Copyright © 2024 MyJoVE Corporation. All rights reserved