Department of Internal Medicine V - Pulmonology,
Allergology,
Respiratory Intensive Care Medicine,
Department of Internal Medicine V - Pulmonology, Allergology, Respiratory Intensive Care Medicine
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Alpha-1-antitrypsin deficiency.
Best practice & research. Clinical gastroenterology Oct, 2010 | Pubmed ID: 20955965
Antibiotic treatment of CF lung disease: from bench to bedside.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society Jun, 2011 | Pubmed ID: 21658633
Serum cortisol predicts death and critical disease independently of CRB-65 score in community-acquired pneumonia: a prospective observational cohort study.
BMC infectious diseases Apr, 2012 | Pubmed ID: 22501026
CDA-2, a urinary preparation, inhibits lung cancer development through the suppression of NF-kappaB activation in myeloid cell.
PloS one , 2012 | Pubmed ID: 23284890
Analysis of the airway microbiota of healthy individuals and patients with chronic obstructive pulmonary disease by T-RFLP and clone sequencing.
PloS one , 2013 | Pubmed ID: 23874580
Probenecid reduces infection and inflammation in acute Pseudomonas aeruginosa pneumonia.
International journal of medical microbiology : IJMM Jul, 2014 | Pubmed ID: 24938792
Moxifloxacin modulates inflammation during murine pneumonia.
Respiratory research Jul, 2014 | Pubmed ID: 25034539
Cathelicidin, an antimicrobial peptide produced by macrophages, promotes colon cancer by activating the Wnt/β-catenin pathway.
Oncotarget Feb, 2015 | Pubmed ID: 25596747
Combined exposure to bacteria and cigarette smoke resembles characteristic phenotypes of human COPD in a murine disease model.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie Mar, 2015 | Pubmed ID: 25601416
Cigarette smoke-promoted acquisition of bacterial pathogens in the upper respiratory tract leads to enhanced inflammation in mice.
Respiratory research Mar, 2015 | Pubmed ID: 25890119
Sex differences in alpha-1-antitrypsin deficiency lung disease-analysis from the German registry.
COPD May, 2015 | Pubmed ID: 25938294
Nanotechnology in respiratory medicine.
Respiratory research May, 2015 | Pubmed ID: 26021823
Chronic inhalation of cigarette smoke reduces phagocytosis in peripheral blood leukocytes.
BMC research notes Nov, 2015 | Pubmed ID: 26597815
The German COPD cohort COSYCONET: Aims, methods and descriptive analysis of the study population at baseline.
Respiratory medicine 05, 2016 | Pubmed ID: 27109808
Results from a large targeted screening program for alpha-1-antitrypsin deficiency: 2003 - 2015.
Orphanet journal of rare diseases 06, 2016 | Pubmed ID: 27282198
Vitamin D Deficiency Does Not Result in a Breach of Host Defense in Murine Models of Pneumonia.
Infection and immunity Nov, 2016 | Pubmed ID: 27400722
Peripheral Artery Disease and Its Clinical Relevance in Patients with Chronic Obstructive Pulmonary Disease in the COPD and Systemic Consequences-Comorbidities Network Study.
American journal of respiratory and critical care medicine 01, 2017 | Pubmed ID: 27532739
Rig-G is a growth inhibitory factor of lung cancer cells that suppresses STAT3 and NF-κB.
Oncotarget 10, 2016 | Pubmed ID: 27602766
Basic science of electronic cigarettes: assessment in cell culture and in vivo models.
Respiratory research 10, 2016 | Pubmed ID: 27717371
Increase of Mast Cell-Nerve Association and Neuropeptide Receptor Expression on Mast Cells in Perennial Allergic Rhinitis.
Neuroimmunomodulation , 2016 | Pubmed ID: 28030866
Transfer factor for carbon monoxide in patients with COPD and diabetes: results from the German COSYCONET cohort.
Respiratory research 01, 2017 | Pubmed ID: 28086884
Allergic airway inflammation induces migration of mast cell populations into the mouse airway.
Cell and tissue research 08, 2017 | Pubmed ID: 28343320
Costs and health-related quality of life in Alpha-1-Antitrypsin Deficient COPD patients.
Respiratory research 04, 2017 | Pubmed ID: 28416015
Three-dimensional ultrashort echo time MRI and Short T images generated from subtraction for determination of tumor burden in lung cancer: Preclinical investigation in transgenic mice.
Magnetic resonance in medicine 02, 2018 | Pubmed ID: 28497643
Relationship of hyperlipidemia to comorbidities and lung function in COPD: Results of the COSYCONET cohort.
PloS one , 2017 | Pubmed ID: 28505167
Deterioration of quality of life is associated with the exacerbation frequency in individuals with alpha-1-antitrypsin deficiency - analysis from the German Registry.
International journal of chronic obstructive pulmonary disease , 2017 | Pubmed ID: 28553095
Exacerbations and duration of smoking abstinence are associated with the annual loss of FEV in individuals with PiZZ alpha-1-antitrypsin deficiency.
Respiratory medicine 08, 2017 | Pubmed ID: 28732839
Cardiovascular risk in patients with alpha-1-antitrypsin deficiency.
Respiratory research 09, 2017 | Pubmed ID: 28915894
Intensive smoking diminishes the differences in quality of life and exacerbation frequency between the alpha-1-antitrypsin deficiency genotypes PiZZ and PiSZ.
Respiratory medicine Sep, 2017 | Pubmed ID: 29206626
Vitamin D and Its Analogues Decrease Amyloid-β (Aβ) Formation and Increase Aβ-Degradation.
International journal of molecular sciences Dec, 2017 | Pubmed ID: 29257109
The revised GOLD 2017 COPD categorization in relation to comorbidities.
Respiratory medicine 01, 2018 | Pubmed ID: 29413512
Hepatic-targeted RNA interference provides robust and persistent knockdown of alpha-1 antitrypsin levels in ZZ patients.
Journal of hepatology 08, 2018 | Pubmed ID: 29572094
Airway obstruction and lung hyperinflation in COPD are linked to an impaired left ventricular diastolic filling.
Respiratory medicine 04, 2018 | Pubmed ID: 29605197
Left ventricular volume and wall stress are linked to lung function impairment in COPD.
International journal of cardiology 06, 2018 | Pubmed ID: 29657040
Cerebral oxygen availability during exercise in COPD patients with cognitive impairment.
Respiratory physiology & neurobiology 08, 2018 | Pubmed ID: 29729396
Uric acid, lung function, physical capacity and exacerbation frequency in patients with COPD: a multi-dimensional approach.
Respiratory research 06, 2018 | Pubmed ID: 29866121
Genome-wide MicroRNA Expression Profiles in COPD: Early Predictors for Cancer Development.
Genomics, proteomics & bioinformatics 06, 2018 | Pubmed ID: 29981854
Large-scale validation of miRNAs by disease association, evolutionary conservation and pathway activity.
RNA biology 01, 2019 | Pubmed ID: 30567465
The composition of the pulmonary microbiota in sarcoidosis - an observational study.
Respiratory research Feb, 2019 | Pubmed ID: 30819175
COPD: Rethinking Patient Management - How to Approach a Challenging Patient Group Successfully.
Respiration; international review of thoracic diseases , 2019 | Pubmed ID: 30879009
Profiling of Alzheimer's disease related genes in mild to moderate vitamin D hypovitaminosis.
The Journal of nutritional biochemistry 05, 2019 | Pubmed ID: 30889441
A murine model to study vasoreactivity and intravascular flow in lung isograft microvessels.
Scientific reports Mar, 2019 | Pubmed ID: 30914786
Effects of airway obstruction and hyperinflation on electrocardiographic axes in COPD.
Respiratory research Mar, 2019 | Pubmed ID: 30917825
Myeloid cell-derived LL-37 promotes lung cancer growth by activating Wnt/β-catenin signaling.
Theranostics , 2019 | Pubmed ID: 31149039
Consequences of chronic kidney disease in chronic obstructive pulmonary disease.
Respiratory research Jul, 2019 | Pubmed ID: 31299972
Low miR-150-5p and miR-320b Expression Predicts Reduced Survival of COPD Patients.
Cells 09, 2019 | Pubmed ID: 31569706
Prevalence of cardiac comorbidities, and their underdetection and contribution to exertional symptoms in COPD: results from the COSYCONET cohort.
International journal of chronic obstructive pulmonary disease , 2019 | Pubmed ID: 31571852
Association of Coding Polymorphism with Lung Function and Serum IL-1β Concentration in Patients Diagnosed with Chronic Obstructive Pulmonary Disease (COPD).
Genes 10, 2019 | Pubmed ID: 31601004
Adherence To Respiratory And Nonrespiratory Medication In Patients With COPD: Results Of The German COSYCONET Cohort.
Patient preference and adherence , 2019 | Pubmed ID: 31631986
The association of cognitive functioning as measured by the DemTect with functional and clinical characteristics of COPD: results from the COSYCONET cohort.
Respiratory research Nov, 2019 | Pubmed ID: 31727165
Time-updated resting heart rate predicts mortality in patients with COPD.
Clinical research in cardiology : official journal of the German Cardiac Society Jun, 2020 | Pubmed ID: 31734762
CAT score single item analysis in patients with COPD: Results from COSYCONET.
Respiratory medicine 11, 2019 | Pubmed ID: 31739262
High-sensitivity troponin I and all-cause mortality in patients with stable COPD: an analysis of the COSYCONET study.
The European respiratory journal Feb, 2020 | Pubmed ID: 31831579
Protocol for the EARCO Registry: a pan-European observational study in patients with α-antitrypsin deficiency.
ERJ open research Jan, 2020 | Pubmed ID: 32154291
Easy measurement of health related quality of life in patients with cystic fibrosis by the COPD assessment test (CAT) - A pilot study.
Respiratory medicine Jul, 2020 | Pubmed ID: 32469708
Carlos Victor Montefusco-Pereira*,1,2,
Justus C. Horstmann*,1,2,
Thomas Ebensen3,
Christoph Beisswenger4,
Robert Bals4,
Carlos A. Guzmán3,
Nicole Schneider-Daum1,
Cristiane de Souza Carvalho-Wodarz1,
Claus-Michael Lehr1,2
1Department of Drug Delivery, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS),
2Department of Pharmacy, Saarland University,
3Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research,
4Department of Internal Medicine V - Pulmonology, Allergology, Respiratory Intensive Care Medicine, Saarland University Hospital
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