Neuroscience Center,
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Neuroscience Center, HiLIFE
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Increased extracellular dopamine concentrations and FosB/DeltaFosB expression in striatal brain areas of heterozygous GDNF knockout mice.
The European journal of neuroscience Nov, 2004 | Pubmed ID: 15525275
In heterozygous GDNF knockout mice the response of striatal dopaminergic system to acute morphine is altered.
Synapse (New York, N.Y.) May, 2006 | Pubmed ID: 16437537
Effects of repeated morphine on locomotion, place preference and dopamine in heterozygous glial cell line-derived neurotrophic factor knockout mice.
Genes, brain, and behavior Apr, 2007 | Pubmed ID: 16879618
Constitutive Ret activity in knock-in multiple endocrine neoplasia type B mice induces profound elevation of brain dopamine concentration via enhanced synthesis and increases the number of TH-positive cells in the substantia nigra.
The Journal of neuroscience : the official journal of the Society for Neuroscience May, 2007 | Pubmed ID: 17475787
Characterization of the striatal dopaminergic neurotransmission in MEN2B mice with elevated cerebral tissue dopamine.
Journal of neurochemistry Jun, 2008 | Pubmed ID: 18248620
Chronic nicotine modifies the effects of morphine on extracellular striatal dopamine and ventral tegmental GABA.
Journal of neurochemistry Nov, 2008 | Pubmed ID: 18786163
WITHDRAWN: Neurorestoration.
Parkinsonism & related disorders Sep, 2011 | Pubmed ID: 21924941
CDNF protects the nigrostriatal dopamine system and promotes recovery after MPTP treatment in mice.
Cell transplantation , 2012 | Pubmed ID: 21943517
Neurorestoration.
Parkinsonism & related disorders Jan, 2012 | Pubmed ID: 22166416
Mesencephalic astrocyte-derived neurotrophic factor (MANF) secretion and cell surface binding are modulated by KDEL receptors.
The Journal of biological chemistry Feb, 2013 | Pubmed ID: 23255601
Local administration of AAV-BDNF to subventricular zone induces functional recovery in stroke rats.
PloS one , 2013 | Pubmed ID: 24312581
Short-term preoperative dietary restriction is neuroprotective in a rat focal stroke model.
PloS one , 2014 | Pubmed ID: 24705386
AAV-mediated targeting of gene expression to the peri-infarct region in rat cortical stroke model.
Journal of neuroscience methods Oct, 2014 | Pubmed ID: 25152446
Prospects of Neurotrophic Factors for Parkinson's Disease: Comparison of Protein and Gene Therapy.
Human gene therapy Aug, 2015 | Pubmed ID: 26176331
Therapeutic potential of the endoplasmic reticulum located and secreted CDNF/MANF family of neurotrophic factors in Parkinson's disease.
FEBS letters Dec, 2015 | Pubmed ID: 26450777
Characterization of a new low-dose 6-hydroxydopamine model of Parkinson's disease in rat.
Journal of neuroscience research Apr, 2016 | Pubmed ID: 26762168
Oral hypoglycaemic effect of GLP-1 and DPP4 inhibitor based nanocomposites in a diabetic animal model.
Journal of controlled release : official journal of the Controlled Release Society 06, 2016 | Pubmed ID: 27091697
Update of neurotrophic factors in neurobiology of addiction and future directions.
Neurobiology of disease 01, 2017 | Pubmed ID: 27189755
Role of microglia in ischemic focal stroke and recovery: focus on Toll-like receptors.
Progress in neuro-psychopharmacology & biological psychiatry 10, 2017 | Pubmed ID: 27389423
Developing therapeutically more efficient Neurturin variants for treatment of Parkinson's disease.
Neurobiology of disease Dec, 2016 | Pubmed ID: 27425888
Accumbal μ-Opioid Receptors Modulate Ethanol Intake in Alcohol-Preferring Alko Alcohol Rats.
Alcoholism, clinical and experimental research 10, 2016 | Pubmed ID: 27508965
AAV Vector-Mediated Gene Delivery to Substantia Nigra Dopamine Neurons: Implications for Gene Therapy and Disease Models.
Genes Feb, 2017 | Pubmed ID: 28208742
Intrastriatally Infused Exogenous CDNF Is Endocytosed and Retrogradely Transported to Substantia Nigra.
eNeuro Jan-Feb, 2017 | Pubmed ID: 28275710
Nigral injection of a proteasomal inhibitor, lactacystin, induces widespread glial cell activation and shows various phenotypes of Parkinson's disease in young and adult mouse.
Experimental brain research 07, 2017 | Pubmed ID: 28439627
9-cis retinoic acid induces neurorepair in stroke brain.
Scientific reports 07, 2017 | Pubmed ID: 28674431
Multifunctional Nanotube-Mucoadhesive Poly(methyl vinyl ether-co-maleic acid)@Hydroxypropyl Methylcellulose Acetate Succinate Composite for Site-Specific Oral Drug Delivery.
Advanced healthcare materials Oct, 2017 | Pubmed ID: 28714596
MANF Promotes Differentiation and Migration of Neural Progenitor Cells with Potential Neural Regenerative Effects in Stroke.
Molecular therapy : the journal of the American Society of Gene Therapy 01, 2018 | Pubmed ID: 29050872
MANF Is Essential for Neurite Extension and Neuronal Migration in the Developing Cortex.
eNeuro Sep-Oct, 2017 | Pubmed ID: 29082311
Development and plasticity of meningeal lymphatic vessels.
The Journal of experimental medicine Dec, 2017 | Pubmed ID: 29141865
Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson's Disease.
Neuroscience 03, 2018 | Pubmed ID: 29408408
Differential Spinal and Supraspinal Activation of Glia in a Rat Model of Morphine Tolerance.
Neuroscience 04, 2018 | Pubmed ID: 29421434
The κ-opioid receptor antagonist JDTic decreases ethanol intake in alcohol-preferring AA rats.
Psychopharmacology 05, 2018 | Pubmed ID: 29492614
Towards developing a model to study alcohol drinking and craving in female mice housed in automated cages.
Behavioural brain research 10, 2018 | Pubmed ID: 29572104
Synthesis of 7β-hydroxy-8-ketone opioid derivatives with antagonist activity at mu- and delta-opioid receptors.
European journal of medicinal chemistry May, 2018 | Pubmed ID: 29649744
Post-stroke Intranasal (+)-Naloxone Delivery Reduces Microglial Activation and Improves Behavioral Recovery from Ischemic Injury.
eNeuro Mar-Apr, 2018 | Pubmed ID: 29766045
Poststroke delivery of MANF promotes functional recovery in rats.
Science advances 05, 2018 | Pubmed ID: 29806020
Pre-α-pro-GDNF and Pre-β-pro-GDNF Isoforms Are Neuroprotective in the 6-hydroxydopamine Rat Model of Parkinson's Disease.
Frontiers in neurology , 2018 | Pubmed ID: 29973907
Implementation of deep neural networks to count dopamine neurons in substantia nigra.
The European journal of neuroscience 09, 2018 | Pubmed ID: 30144349
Downregulation of tyrosine hydroxylase phenotype after AAV injection above substantia nigra: Caution in experimental models of Parkinson's disease.
Journal of neuroscience research 03, 2019 | Pubmed ID: 30548446
Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats.
Neuron 04, 2019 | Pubmed ID: 30792150
Secondary Pathology of the Thalamus after Focal Cortical Stroke in Rats is not Associated with Thermal or Mechanical Hypersensitivity and is Not Alleviated by Intra-Thalamic Post-Stroke Delivery of Recombinant CDNF or MANF.
Cell transplantation 04, 2019 | Pubmed ID: 31037983
Neuroprotective and reparative effects of endoplasmic reticulum luminal proteins - mesencephalic astrocyte-derived neurotrophic factor and cerebral dopamine neurotrophic factor.
Croatian medical journal Apr, 2019 | Pubmed ID: 31044581
Effects of Neurotrophic Factors in Glial Cells in the Central Nervous System: Expression and Properties in Neurodegeneration and Injury.
Frontiers in physiology , 2019 | Pubmed ID: 31105589
Cerebral Dopamine Neurotrophic Factor Diffuses Around the Brainstem and Does Not Undergo Anterograde Transport After Injection to the Substantia Nigra.
Frontiers in neuroscience , 2019 | Pubmed ID: 31244598
Neuronal Activation Stimulates Cytomegalovirus Promoter-Driven Transgene Expression.
Molecular therapy. Methods & clinical development Sep, 2019 | Pubmed ID: 31380464
Engineered antibody-functionalized porous silicon nanoparticles for therapeutic targeting of pro-survival pathway in endogenous neuroblasts after stroke.
Biomaterials 01, 2020 | Pubmed ID: 31670035
Cerebral dopamine neurotrophic factor-deficiency leads to degeneration of enteric neurons and altered brain dopamine neuronal function in mice.
Neurobiology of disease 02, 2020 | Pubmed ID: 31783118
MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System.
eNeuro Jan/Feb, 2020 | Pubmed ID: 32005751
Back and to the Future: From Neurotoxin-Induced to Human Parkinson's Disease Models.
Current protocols in neuroscience Mar, 2020 | Pubmed ID: 32049438
Molecular profile of the rat peri-infarct region four days after stroke: Study with MANF.
Experimental neurology Jul, 2020 | Pubmed ID: 32229226
Mitoxantrone, pixantrone and mitoxantrone (2-hydroxyethyl)piperazine are toll-like receptor 4 antagonists, inhibit NF-κB activation, and decrease TNF-alpha secretion in primary microglia.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Jul, 2020 | Pubmed ID: 32730846
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