Institute of Virology
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Correlation between serotonin uptake in human blood platelets with the 44-bp polymorphism and the 17-bp variable number of tandem repeat of the serotonin transporter.
American journal of medical genetics Apr, 2002 | Pubmed ID: 11920857
Simultaneous determination of ondansetron and tropisetron in human plasma using HPLC with UV detection.
Biomedical chromatography : BMC May, 2002 | Pubmed ID: 11920943
Validity of PCR with emphasis on variable number of tandem repeat analysis.
Clinical biochemistry Feb, 2002 | Pubmed ID: 11937078
Efficacy and safety of abacavir plus efavirenz as a salvage regimen in HIV-infected individuals after 48 weeks.
AIDS (London, England) May, 2002 | Pubmed ID: 11953478
Diversity and complexity of HIV-1 drug resistance: a bioinformatics approach to predicting phenotype from genotype.
Proceedings of the National Academy of Sciences of the United States of America Jun, 2002 | Pubmed ID: 12060770
Patient-tailored antiemetic treatment with 5-hydroxytryptamine type 3 receptor antagonists according to cytochrome P-450 2D6 genotypes.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Jun, 2002 | Pubmed ID: 12065557
Risk of hepatitis C after immunoadsorption.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America Jun, 2002 | Pubmed ID: 12083240
Frequency of the 17-bp variable number of tandem repeat polymorphism in Turkish schizophrenic patients.
Schizophrenia research Nov, 2002 | Pubmed ID: 12363397
Variations in the 5-hydroxytryptamine type 3B receptor gene as predictors of the efficacy of antiemetic treatment in cancer patients.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Jun, 2003 | Pubmed ID: 12775740
Geno2pheno: Estimating phenotypic drug resistance from HIV-1 genotypes.
Nucleic acids research Jul, 2003 | Pubmed ID: 12824435
Methods for optimizing antiviral combination therapies.
Bioinformatics (Oxford, England) , 2003 | Pubmed ID: 12855433
Tenofovir resistance and resensitization.
Antimicrobial agents and chemotherapy Nov, 2003 | Pubmed ID: 14576105
Variations in the genes encoding the peroxisome proliferator-activated receptors alpha and gamma in psoriasis.
Archives of dermatological research Jun, 2004 | Pubmed ID: 15083308
Meta-analysis of the dopamine D3 receptor gene (DRD3) Ser9Gly variant and schizophrenia.
Psychiatric genetics Mar, 2004 | Pubmed ID: 15091310
Investigation of the association between 5-HT3A receptor gene polymorphisms and efficiency of antiemetic treatment with 5-HT3 receptor antagonists.
Pharmacogenetics May, 2004 | Pubmed ID: 15115912
Pharmacogenetics-based new therapeutic concepts.
Drug metabolism reviews Oct, 2004 | Pubmed ID: 15554239
Successful therapy of hepatitis B with tenofovir in HIV-infected patients failing previous adefovir and lamivudine treatment.
AIDS (London, England) Nov, 2004 | Pubmed ID: 15577546
Mtreemix: a software package for learning and using mixture models of mutagenetic trees.
Bioinformatics (Oxford, England) May, 2005 | Pubmed ID: 15657098
Estimating HIV evolutionary pathways and the genetic barrier to drug resistance.
The Journal of infectious diseases Jun, 2005 | Pubmed ID: 15871130
Antiemetic guidelines: are they being used?
The lancet oncology Aug, 2005 | Pubmed ID: 16054573
Comparison of GB virus C, HIV, and HCV infection markers in hemophiliacs exposed to non-inactivated or inactivated factor concentrates.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Sep, 2005 | Pubmed ID: 16087123
Learning multiple evolutionary pathways from cross-sectional data.
Journal of computational biology : a journal of computational molecular cell biology Jul-Aug, 2005 | Pubmed ID: 16108705
Computational methods for the design of effective therapies against drug resistant HIV strains.
Bioinformatics (Oxford, England) Nov, 2005 | Pubmed ID: 16144807
Evolution of HIV resistance during treatment interruption in experienced patients and after restarting a new therapy.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Dec, 2005 | Pubmed ID: 16191482
Basics of the virology of HIV-1 and its replication.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Dec, 2005 | Pubmed ID: 16198625
Bioinformatics approach to predicting HIV drug resistance.
Expert review of molecular diagnostics Mar, 2006 | Pubmed ID: 16512780
Primary HIV drug resistance and efficacy of first-line antiretroviral therapy guided by resistance testing.
Journal of acquired immune deficiency syndromes (1999) Apr, 2006 | Pubmed ID: 16652031
Variations in the peroxisome proliferator-activated receptor-gamma gene and melanoma risk.
Cancer letters Feb, 2007 | Pubmed ID: 16713673
Detection of bocavirus DNA in nasopharyngeal aspirates of a child with bronchiolitis.
The Journal of infection Mar, 2007 | Pubmed ID: 16968654
Stable coreceptor usage of HIV in patients with ongoing treatment failure on HAART.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Dec, 2006 | Pubmed ID: 17005445
Functional domains of the human immunodeficiency virus type 1 Nef protein are conserved among different clades in Cameroon.
AIDS research and human retroviruses Oct, 2006 | Pubmed ID: 17067262
Variations of the melanocortin-1 receptor and the glutathione-S transferase T1 and M1 genes in cutaneous malignant melanoma.
Archives of dermatological research Jan, 2007 | Pubmed ID: 17072629
Reactivation of an occult hepatitis B virus escape mutant in an anti-HBs positive, anti-HBc negative lymphoma patient.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Jan, 2007 | Pubmed ID: 17134939
Severe pneumonia and human bocavirus in adult.
Emerging infectious diseases Oct, 2006 | Pubmed ID: 17176591
Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients.
Antiviral therapy , 2006 | Pubmed ID: 17302250
A novel internally controlled real-time reverse transcription-PCR assay for HIV-1 RNA targeting the pol integrase genomic region.
Journal of virological methods Jun, 2007 | Pubmed ID: 17321607
Improved prediction of response to antiretroviral combination therapy using the genetic barrier to drug resistance.
Antiviral therapy , 2007 | Pubmed ID: 17503659
Genetic polymorphisms in the amino acid transporters LAT1 and LAT2 in relation to the pharmacokinetics and side effects of melphalan.
Pharmacogenetics and genomics Jul, 2007 | Pubmed ID: 17558306
Frequent detection of cell-associated HIV-1 RNA in patients with plasma viral load <50 copies/ml.
Journal of medical virology Oct, 2007 | Pubmed ID: 17705170
Trends of prevalence of primary HIV drug resistance in Germany.
The Journal of antimicrobial chemotherapy Oct, 2007 | Pubmed ID: 17715124
Selective pressures of HLA genotypes and antiviral therapy on human immunodeficiency virus type 1 sequence mutation at a population level.
Clinical and vaccine immunology : CVI Oct, 2007 | Pubmed ID: 17715334
Fifteen years of env C2V3C3 evolution in six individuals infected clonally with human immunodeficiency virus type 1.
Journal of medical virology Nov, 2007 | Pubmed ID: 17854039
Predicting HIV coreceptor usage on the basis of genetic and clinical covariates.
Antiviral therapy , 2007 | Pubmed ID: 18018768
Bioinformatics prediction of HIV coreceptor usage.
Nature biotechnology Dec, 2007 | Pubmed ID: 18066037
Functional characterization of a -100_-102delAAG deletion-insertion polymorphism in the promoter region of the HTR3B gene.
Pharmacogenetics and genomics Mar, 2008 | Pubmed ID: 18300944
Serotonin transporter gene and response to lithium augmentation in depression.
Psychiatric genetics Apr, 2008 | Pubmed ID: 18349701
Selecting anti-HIV therapies based on a variety of genomic and clinical factors.
Bioinformatics (Oxford, England) Jul, 2008 | Pubmed ID: 18586740
Comparison of classifier fusion methods for predicting response to anti HIV-1 therapy.
PloS one , 2008 | Pubmed ID: 18941628
Genotypic antiretroviral resistance testing for human immunodeficiency virus type 1 integrase inhibitors by use of the TruGene sequencing system.
Journal of clinical microbiology Dec, 2008 | Pubmed ID: 18945845
Phase I dose escalation and pharmacokinetic study of BI 2536, a novel Polo-like kinase 1 inhibitor, in patients with advanced solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology Dec, 2008 | Pubmed ID: 18955456
Prevalence of C-terminal gag cleavage site mutations in HIV from therapy-naïve patients.
The Journal of infection Jan, 2009 | Pubmed ID: 19110315
Predicting the response to combination antiretroviral therapy: retrospective validation of geno2pheno-THEO on a large clinical database.
The Journal of infectious diseases Apr, 2009 | Pubmed ID: 19239365
Prevalence of minor variants of HIV strains at reverse transcriptase position 103 in therapy-naïve patients and their impact on the virological failure.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology May, 2009 | Pubmed ID: 19375978
Advantages of predicted phenotypes and statistical learning models in inferring virological response to antiretroviral therapy from HIV genotype.
Antiviral therapy , 2009 | Pubmed ID: 19430102
Evolution of raltegravir resistance during therapy.
The Journal of antimicrobial chemotherapy Jul, 2009 | Pubmed ID: 19447792
Kinetic binding analysis of aptamers targeting HIV-1 proteins by a combination of a microbalance array and mass spectrometry (MAMS).
Journal of proteome research Jul, 2009 | Pubmed ID: 19469583
[Resistance screening].
MMW Fortschritte der Medizin Apr, 2009 | Pubmed ID: 19769083
Seasonal influenza virus species in patient swab samples analyzed for the presence of the pandemic (H1N1) 2009 influenza virus.
Journal of clinical microbiology Dec, 2009 | Pubmed ID: 19794039
V3 loop sequence space analysis suggests different evolutionary patterns of CCR5- and CXCR4-tropic HIV.
PloS one , 2009 | Pubmed ID: 19816596
When and how to use maraviroc in HIV-infected patients.
AIDS (London, England) Nov, 2009 | Pubmed ID: 19834318
High prevalence of bevirimat resistance mutations in protease inhibitor-resistant HIV isolates.
AIDS (London, England) Mar, 2010 | Pubmed ID: 19926962
Phase I study of the angiogenesis inhibitor BIBF 1120 in patients with advanced solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research Jan, 2010 | Pubmed ID: 20028771
The evolution of protease mutation 76V is associated with protease mutation 46I and gag mutation 431V.
AIDS (London, England) Mar, 2010 | Pubmed ID: 20139751
Only slight impact of predicted replicative capacity for therapy response prediction.
PloS one , 2010 | Pubmed ID: 20140263
Short communication: selection of thymidine analogue resistance mutational patterns in children infected from a common HIV type 1 subtype G source.
AIDS research and human retroviruses Mar, 2010 | Pubmed ID: 20334563
Evolution of protease inhibitor resistance in the gag and pol genes of HIV subtype G isolates.
The Journal of antimicrobial chemotherapy Jul, 2010 | Pubmed ID: 20430786
Phase I open-label study of continuous treatment with BIBF 1120, a triple angiokinase inhibitor, and pemetrexed in pretreated non-small cell lung cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research May, 2010 | Pubmed ID: 20460487
Phase I safety, pharmacokinetic, and biomarker study of BIBF 1120, an oral triple tyrosine kinase inhibitor in patients with advanced solid tumors.
Molecular cancer therapeutics Oct, 2010 | Pubmed ID: 20688946
Analysis of immune selection as a potential cause for the presence of cleavage site mutation 431V in treatment-naive HIV type-1 isolates.
Antiviral therapy , 2010 | Pubmed ID: 20834103
Prevalence and characteristics of hepatitis B and C virus infections in treatment-naïve HIV-infected patients.
Medical microbiology and immunology Feb, 2011 | Pubmed ID: 20853118
Improved prediction of HIVâ€1 coreceptor usage with sequence information from the second hypervariable loop of gp120.
The Journal of infectious diseases Nov, 2010 | Pubmed ID: 20874088
Hepatitis B virus reverse transcriptase sequence variant database for sequence analysis and mutation discovery.
Antiviral research Dec, 2010 | Pubmed ID: 20875460
Characterisation of the epitope for a herpes simplex virus glycoprotein B-specific monoclonal antibody with high protective capacity.
Medical microbiology and immunology May, 2011 | Pubmed ID: 20931340
Prevalence of key resistance mutations K65R, K103N, and M184V as minority HIV-1 variants in chronically HIV-1 infected, treatment-naïve patients.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology Feb, 2011 | Pubmed ID: 21056001
Antiretroviral therapy optimisation without genotype resistance testing: a perspective on treatment history based models.
PloS one , 2010 | Pubmed ID: 21060792
Influence of major HIV-1 protease inhibitor resistance mutations on CTL recognition.
Journal of acquired immune deficiency syndromes (1999) Feb, 2011 | Pubmed ID: 21107269
Changes in the HIV-1 mutational profile before first-line HAART in the RESINA cohort.
Journal of medical virology Feb, 2011 | Pubmed ID: 21181911
Pharmacokinetics and metabolism of BIBF 1120 after oral dosing to healthy male volunteers.
Xenobiotica; the fate of foreign compounds in biological systems Apr, 2011 | Pubmed ID: 21204634
The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir: is there a clinical advantage?
AIDS research and therapy , 2011 | Pubmed ID: 21314993
Treatment of lung cancer patients and concomitant use of drugs interacting with cytochrome P450 isoenzymes.
Lung cancer (Amsterdam, Netherlands) Oct, 2011 | Pubmed ID: 21382644
HIV prevalence and route of transmission in Turkish immigrants living in North-Rhine Westphalia, Germany.
Medical microbiology and immunology Nov, 2011 | Pubmed ID: 21461764
The SnoB study: frequency of baseline raltegravir resistance mutations prevalence in different non-B subtypes.
Medical microbiology and immunology Nov, 2011 | Pubmed ID: 21475993
Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis.
BMC medical informatics and decision making , 2011 | Pubmed ID: 21569501
APOBEC3G/F as one possible driving force for co-receptor switch of the human immunodeficiency virus-1.
Medical microbiology and immunology Feb, 2012 | Pubmed ID: 21573951
Detection of drug resistance mutations at low plasma HIV-1 RNA load in a European multicentre cohort study.
The Journal of antimicrobial chemotherapy Aug, 2011 | Pubmed ID: 21624929
Severe human bocavirus infection, Germany.
Emerging infectious diseases Dec, 2011 | Pubmed ID: 22172367
Mutational patterns in the frameshift-regulating site of HIV-1 selected by protease inhibitors.
Medical microbiology and immunology Dec, 2011 | Pubmed ID: 22200908
Endogenous or exogenous spreading of HIV-1 in Nordrhein-Westfalen, Germany, investigated by phylodynamic analysis of the RESINA Study cohort.
Medical microbiology and immunology Jan, 2012 | Pubmed ID: 22262052
HIV-GRADE: A Publicly Available, Rules-Based Drug Resistance Interpretation Algorithm Integrating Bioinformatic Knowledge.
Intervirology , 2012 | Pubmed ID: 22286877
Predicting Response to Antiretroviral Treatment by Machine Learning: The EuResist Project.
Intervirology , 2012 | Pubmed ID: 22286881
Risk Factors Associated with Older Age in Treatment-Naive HIV-Positive Patients.
Intervirology , 2012 | Pubmed ID: 22286885
Epidemiology of Transmitted Drug Resistance in Chronically HIV-Infected Patients in Germany: The RESINA Study 2001-2009.
Intervirology , 2012 | Pubmed ID: 22286886
Efficacy of Antiretroviral Therapy Switch in HIV-Infected Patients: A 10-Year Analysis of the EuResist Cohort.
Intervirology , 2012 | Pubmed ID: 22286887
How Individual Can Personalized Antiretroviral Treatment Be? Deep Salvage in an HIV-1-Infected Patient.
Intervirology , 2012 | Pubmed ID: 22286888
Saleta Sierra1,
Rolf Kaiser1,
Nadine Lübke1,
Alexander Thielen2,
Eugen Schuelter1,
Eva Heger1,
Martin Däumer3,
Stefan Reuter4,
Stefan Esser5,
Gerd Fätkenheuer6,
Herbert Pfister1,
Mark Oette7,
Thomas Lengauer2
1Institute of Virology, University of Cologne,
2, Max Planck Institute for Informatics,
3, Institute for Immune genetics,
4Department of Gastroenterology, Hepatology and Infectiology, University of Duesseldorf,
5Department of Dermatology, University of Essen,
6Department of Internal Medicine, University of Cologne,
7, Augustinerinnen Hospital
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