Department of Urology
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Mechanical stretch is a highly selective regulator of gene expression in human bladder smooth muscle cells.
Physiological genomics Dec, 2004 | Pubmed ID: 15467014
Recent insights into the cell biology of bladder smooth muscle.
Nephron. Experimental nephrology , 2006 | Pubmed ID: 16179802
GATA-6 mediates human bladder smooth muscle differentiation: involvement of a novel enhancer element in regulating alpha-smooth muscle actin gene expression.
American journal of physiology. Cell physiology Sep, 2007 | Pubmed ID: 17626241
Rapid preparation of nuclei-depleted detergent-resistant membrane fractions suitable for proteomics analysis.
BMC cell biology Jun, 2008 | Pubmed ID: 18534013
JunB mediates basal- and TGFβ1-induced smooth muscle cell contractility.
PloS one , 2013 | Pubmed ID: 23308222
Evaluation of silk biomaterials in combination with extracellular matrix coatings for bladder tissue engineering with primary and pluripotent cells.
PloS one , 2013 | Pubmed ID: 23409160
The performance of silk scaffolds in a rat model of augmentation cystoplasty.
Biomaterials Jul, 2013 | Pubmed ID: 23545287
The impact of discrete modes of spinal cord injury on bladder muscle contractility.
BMC urology May, 2013 | Pubmed ID: 23668225
Loss of caveolin-1 in prostate cancer stroma correlates with reduced relapse-free survival and is functionally relevant to tumour progression.
The Journal of pathology Sep, 2013 | Pubmed ID: 23729330
Loss of Sh3gl2/endophilin A1 is a common event in urothelial carcinoma that promotes malignant behavior.
Neoplasia (New York, N.Y.) Jul, 2013 | Pubmed ID: 23814487
Bladder tissue regeneration using acellular bi-layer silk scaffolds in a large animal model of augmentation cystoplasty.
Biomaterials Nov, 2013 | Pubmed ID: 23953839
Acellular bi-layer silk fibroin scaffolds support tissue regeneration in a rabbit model of onlay urethroplasty.
PloS one , 2014 | Pubmed ID: 24632740
The use of bi-layer silk fibroin scaffolds and small intestinal submucosa matrices to support bladder tissue regeneration in a rat model of spinal cord injury.
Biomaterials Aug, 2014 | Pubmed ID: 24917031
Progress made in the use of animal models for the study of high-risk, nonmuscle invasive bladder cancer.
Current opinion in urology Sep, 2014 | Pubmed ID: 24921908
Integration of proteomic and transcriptomic profiles identifies a novel PDGF-MYC network in human smooth muscle cells.
Cell communication and signaling : CCS Aug, 2014 | Pubmed ID: 25080971
Pathophysiology and animal modeling of underactive bladder.
International urology and nephrology Sep, 2014 | Pubmed ID: 25238890
Dynamic reciprocity in cell-scaffold interactions.
Advanced drug delivery reviews Mar, 2015 | Pubmed ID: 25453262
Platelet Derived Growth Factor Has a Role in Pressure Induced Bladder Smooth Muscle Cell Hyperplasia and Acts in a Paracrine Way.
The Journal of urology Dec, 2015 | Pubmed ID: 26055827
Regulation of microtubule dynamics by DIAPH3 influences amoeboid tumor cell mechanics and sensitivity to taxanes.
Scientific reports Jul, 2015 | Pubmed ID: 26179371
Mutations in TBX18 Cause Dominant Urinary Tract Malformations via Transcriptional Dysregulation of Ureter Development.
American journal of human genetics Aug, 2015 | Pubmed ID: 26235987
Inosine Improves Neurogenic Detrusor Overactivity following Spinal Cord Injury.
PloS one , 2015 | Pubmed ID: 26529505
Inflammation and Lymphedema Are Exacerbated and Prolonged by Neuropilin 2 Deficiency.
The American journal of pathology 11, 2016 | Pubmed ID: 27751443
Deletion of neuropilin 2 enhances detrusor contractility following bladder outlet obstruction.
JCI insight 02, 2017 | Pubmed ID: 28194441
MYC Mediates Large Oncosome-Induced Fibroblast Reprogramming in Prostate Cancer.
Cancer research 05, 2017 | Pubmed ID: 28202510
Inosine attenuates spontaneous activity in the rat neurogenic bladder through an A pathway.
Scientific reports 03, 2017 | Pubmed ID: 28294142
The Cytotoxicity and Genotoxicity of Particulate and Soluble Cobalt in Human Urothelial Cells.
Biological trace element research Nov, 2017 | Pubmed ID: 28324276
The role of the mucosa in modulation of evoked responses in the spinal cord injured rat bladder.
Neurourology and urodynamics 06, 2018 | Pubmed ID: 29427331
Heparin-Binding Epidermal Growth Factor-Like Growth Factor as a Critical Mediator of Tissue Repair and Regeneration.
The American journal of pathology 11, 2018 | Pubmed ID: 30142332
Inosine - a Multifunctional Treatment for Complications of Neurologic Injury.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology , 2018 | Pubmed ID: 30261493
Immunology, Immunotherapy, and Translating Basic Science into the Clinic for Bladder Cancer.
Bladder cancer (Amsterdam, Netherlands) Oct, 2018 | Pubmed ID: 30417054
Genome-wide CRISPR screens for Shiga toxins and ricin reveal Golgi proteins critical for glycosylation.
PLoS biology 11, 2018 | Pubmed ID: 30481169
Concordant miRNA and mRNA expression profiles in humans and mice with bladder outlet obstruction.
American journal of clinical and experimental urology , 2018 | Pubmed ID: 30697578
MCL1 and DEDD Promote Urothelial Carcinoma Progression.
Molecular cancer research : MCR 06, 2019 | Pubmed ID: 30777879
A multi-omics approach to understanding the field effect in bladder cancer.
Translational andrology and urology Dec, 2019 | Pubmed ID: 32038978
Systems analysis of benign bladder disorders: insights from omics analysis.
American journal of physiology. Renal physiology Apr, 2020 | Pubmed ID: 32116016
Hussein Atta*,1,2,
Ali Hashemi Gheinani*,1,2,
Amanda Wacker1,
Yaser Heshmati3,4,5,
Alex Bigger-Allen1,6,
George Lambrinos1,2,
Yao Gao2,7,
Diane R. Bielenberg2,7,
Rosalyn M. Adam1,2
1Department of Urology, Boston Children's Hospital,
2Department of Surgery, Harvard Medical School,
3Division of Hematology/Oncology, Harvard Medical School Boston,
4, Dana-Farber Cancer Institute,
5, Broad Institute,
6Biological Biomedical Sciences Program, Division of Medical Sciences, Harvard Medical School,
7Vascular Biology Program, Boston Children's Hospital
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