After a PhD in Biophysics in Paris and 10 years working in the team of Maité Coppey at Jacques Monod Institute (Université Paris Diderot), Marc Tramier moved to Rennes at IGDR to set up his own team. The team aims at developing techniques and methodologies in fluorescence microscopy to study dynamics of protein-protein interactions and biochemical activities in live sample. Team approaches are mainly driven by methodological and technological development, its transfer and its applicability in biology to answer relevant new questions.