Department of Gerontology and Geriatrics,
Netherlands Consortium for Healthy Aging
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Persistence of high-replicative capacity in cultured fibroblasts from nonagenarians.
Aging cell Feb, 2007 | Pubmed ID: 17266674
Beta-galactosidase activity as a biomarker of replicative senescence during the course of human fibroblast cultures.
Annals of the New York Academy of Sciences Apr, 2007 | Pubmed ID: 17460195
High prevalence of cytomegalovirus DNA in plasma samples of blood donors in connection with seroconversion.
Transfusion Nov, 2007 | Pubmed ID: 17958525
Relation between body height and replicative capacity of human fibroblasts in nonagenarians.
The journals of gerontology. Series A, Biological sciences and medical sciences Jan, 2008 | Pubmed ID: 18245759
Influence of the TP53 codon 72 polymorphism on the cellular responses to X-irradiation in fibroblasts from nonagenarians.
Mechanisms of ageing and development Apr, 2008 | Pubmed ID: 18272203
Colony formation and colony size do not reflect the onset of replicative senescence in human fibroblasts.
The journals of gerontology. Series A, Biological sciences and medical sciences Jul, 2008 | Pubmed ID: 18693218
Relation between replicative senescence of human fibroblasts and life history characteristics.
Ageing research reviews Jul, 2009 | Pubmed ID: 19491042
Stress-induced responses of human skin fibroblasts in vitro reflect human longevity.
Aging cell Sep, 2009 | Pubmed ID: 19681808
Rapid flow cytometric method for measuring senescence associated beta-galactosidase activity in human fibroblasts.
Cytometry. Part A : the journal of the International Society for Analytical Cytology Nov, 2009 | Pubmed ID: 19777541
Handgrip strength and mortality in the oldest old population: the Leiden 85-plus study.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne Mar, 2010 | Pubmed ID: 20142372
Handgrip strength as a predictor of functional, psychological and social health. A prospective population-based study among the oldest old.
Age and ageing May, 2010 | Pubmed ID: 20219767
Patterns of muscle strength loss with age in the general population and patients with a chronic inflammatory state.
Ageing research reviews Oct, 2010 | Pubmed ID: 20553969
Trajectories of disability in the last year of life.
The New England journal of medicine Jul, 2010 | Pubmed ID: 20665928
Higher blood pressure is associated with higher handgrip strength in the oldest old.
American journal of hypertension Jan, 2011 | Pubmed ID: 20814409
Immunosenescence and Cytomegalovirus: where do we stand after a decade?
Immunity & ageing : I & A , 2010 | Pubmed ID: 20822513
Hallmark features of immunosenescence are absent in familial longevity.
Journal of immunology (Baltimore, Md. : 1950) Oct, 2010 | Pubmed ID: 20855876
Relation between maximum replicative capacity and oxidative stress-induced responses in human skin fibroblasts in vitro.
The journals of gerontology. Series A, Biological sciences and medical sciences Jan, 2011 | Pubmed ID: 20937674
Circulating levels of IGF1 are associated with muscle strength in middle-aged- and oldest-old women.
European journal of endocrinology / European Federation of Endocrine Societies Feb, 2011 | Pubmed ID: 21135066
An unopposed proinflammatory response is beneficial for survival in the oldest old. Results of the Leiden 85-plus Study.
The journals of gerontology. Series A, Biological sciences and medical sciences Apr, 2011 | Pubmed ID: 21177757
Functional interplay between mitochondrial and proteasome activity in skin aging.
The Journal of investigative dermatology Mar, 2011 | Pubmed ID: 21191400
C-reactive protein and glucose regulation in familial longevity.
Age (Dordrecht, Netherlands) Dec, 2011 | Pubmed ID: 21246407
Serum triiodothyronine levels and inflammatory cytokine production capacity.
Age (Dordrecht, Netherlands) Feb, 2012 | Pubmed ID: 21350816
Homocysteine and familial longevity: the Leiden Longevity Study.
PloS one , 2011 | Pubmed ID: 21408159
Accuracy of direct segmental multi-frequency bioimpedance analysis in the assessment of total body and segmental body composition in middle-aged adult population.
Clinical nutrition (Edinburgh, Scotland) Oct, 2011 | Pubmed ID: 21555168
Infection with cytomegalovirus but not herpes simplex virus induces the accumulation of late-differentiated CD4+ and CD8+ T-cells in humans.
The Journal of general virology Dec, 2011 | Pubmed ID: 21813708
Handgrip strength at midlife and familial longevity : The Leiden Longevity Study.
Age (Dordrecht, Netherlands) Oct, 2012 | Pubmed ID: 21833741
Responsiveness of the innate immune system and glucose concentrations in the oldest old.
Age (Dordrecht, Netherlands) Aug, 2012 | Pubmed ID: 21833742
Morphometric skin characteristics dependent on chronological and biological age: the Leiden Longevity Study.
Age (Dordrecht, Netherlands) Dec, 2012 | Pubmed ID: 21909657
Marked heterogeneity in growth characteristics of myoblast clonal cultures and myoblast mixed cultures obtained from the same individual.
Gerontology , 2012 | Pubmed ID: 21921572
Report from the second cytomegalovirus and immunosenescence workshop.
Immunity & ageing : I & A , 2011 | Pubmed ID: 22035114
Chronic inhibition of the respiratory chain in human fibroblast cultures: differential responses related to subject chronological and biological age.
The journals of gerontology. Series A, Biological sciences and medical sciences May, 2012 | Pubmed ID: 22080500
High serum glucose levels are associated with a higher perceived age.
Age (Dordrecht, Netherlands) Nov, 2011 | Pubmed ID: 22102339
Regenerative potential of human muscle stem cells in chronic inflammation.
Arthritis research & therapy , 2011 | Pubmed ID: 22171690
Spinal reflex properties in the long term after stroke.
Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology Apr, 2012 | Pubmed ID: 22196888
[Comprehensive geriatric assessment: unfeasible and undesirable].
Nederlands tijdschrift voor geneeskunde , 2012 | Pubmed ID: 22217309
Human in vivo longevity is reflected in vitro by differential metabolism as measured by (1)H-NMR profiling of cell culture supernatants.
Molecular bioSystems Mar, 2012 | Pubmed ID: 22218423
Risk factors for failure to return to the pre-fracture place of residence after hip fracture: a prospective longitudinal study of 444 patients.
Archives of orthopaedic and trauma surgery Jun, 2012 | Pubmed ID: 22311748
Familial longevity is marked by lower diurnal salivary cortisol levels: the Leiden Longevity Study.
PloS one , 2012 | Pubmed ID: 22348049
Temporal relationship between handgrip strength and cognitive performance in oldest old people.
Age and ageing Jul, 2012 | Pubmed ID: 22374646
Cortisol serum levels in familial longevity and perceived age: the Leiden longevity study.
Psychoneuroendocrinology Oct, 2012 | Pubmed ID: 22429748
The number of p16INK4a positive cells in human skin reflects biological age.
Aging cell Aug, 2012 | Pubmed ID: 22612594
Total joint replacement in the past does not relate to a deteriorated functional level and health status in the oldest old.
Journal of aging research , 2012 | Pubmed ID: 22649729
Lower proportion of naïve peripheral CD8+ T cells and an unopposed pro-inflammatory response to human Cytomegalovirus proteins in vitro are associated with longer survival in very elderly people.
Age (Dordrecht, Netherlands) Jun, 2012 | Pubmed ID: 22661297
Do clinical characteristics and outcome in nonagenarians with a hip fracture differ from younger patients?
Geriatrics & gerontology international Jun, 2012 | Pubmed ID: 22686522
Microarray-based identification of age-dependent differences in gene expression of human dermal fibroblasts.
Mechanisms of ageing and development Jul, 2012 | Pubmed ID: 22721680
More than half of hip fracture patients do not regain mobility in the first postoperative year.
Geriatrics & gerontology international Jun, 2012 | Pubmed ID: 22726959
The effect of chronological age on the inflammatory response of human fibroblasts.
Experimental gerontology Sep, 2012 | Pubmed ID: 22790019
Muscle characteristics in patients with chronic systemic inflammation.
Muscle & nerve Aug, 2012 | Pubmed ID: 22806369
Facial Appearance Reflects Human Familial Longevity and Cardiovascular Disease Risk in Healthy Individuals.
The journals of gerontology. Series A, Biological sciences and medical sciences Aug, 2012 | Pubmed ID: 22879455
Brain tissue volumes in familial longevity: the Leiden Longevity Study.
Aging cell Aug, 2012 | Pubmed ID: 22882385
Cytomegalovirus seropositivity is associated with glucose regulation in the oldest old. Results from the Leiden 85-plus Study.
Immunity & ageing : I & A , 2012 | Pubmed ID: 22929089
Parasitic infections and immune function: Effect of helminth infections in a malaria endemic area.
Immunobiology Aug, 2012 | Pubmed ID: 22999162
Predicting Survival in Oldest Old People.
The American journal of medicine Sep, 2012 | Pubmed ID: 23017181
Metabolic health in families enriched for longevity is associated with low prevalence of hand osteoarthritis and influences OA biomarker profiles.
Annals of the rheumatic diseases Oct, 2012 | Pubmed ID: 23104762
CMV and Immunosenescence: from basics to clinics.
Immunity & ageing : I & A Oct, 2012 | Pubmed ID: 23114110
High Blood Pressure and Resilience to Physical and Cognitive Decline in the Oldest Old: The Leiden 85-Plus Study.
Journal of the American Geriatrics Society Nov, 2012 | Pubmed ID: 23126669
Levels of 25-hydroxyvitamin D in familial longevity: the Leiden Longevity Study.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne Nov, 2012 | Pubmed ID: 23128285
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