Yoichi Takakusagi

Institute of Quantum Life Science, National Institutes for Quantum and Radiological Science and Technology

Affiliated withNational Institutes for Quantum and Radiological Science and Technology National Institutes for Quantum Science and Technology chiba university

Research Area

Bioengineering

Biography

JoVE Journal Publications

Article Total : 2	Year
Publication title	2020
Publication title	2025

Other Publications

Article	Year
[Validation of small-molecule/protein interactions by the T7 phage display strategy using a quartz-crystal microbalance device]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme\| PubMed ID: 19588885	2009
Use of phage display technology for the determination of the targets for small-molecule therapeutics. Expert opinion on drug discovery\| PubMed ID: 22823088	2010
Multimodal biopanning of T7 phage-displayed peptides reveals angiomotin as a potential receptor of the anti-angiogenic macrolide Roxithromycin. European journal of medicinal chemistry\| PubMed ID: 25528335	2015
Direct Monitoring of γ-Glutamyl Transpeptidase Activity In Vivo Using a Hyperpolarized (13) C-Labeled Molecular Probe. Angewandte Chemie (International ed. in English)\| PubMed ID: 27483206	2016
Hyperpolarized [1-C]-Pyruvate Magnetic Resonance Spectroscopic Imaging of Prostate Cancer Predicts Efficacy of Targeting the Warburg Effect. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 29599412	2018
Intratumoral evaluation of 3D microvasculature and nanoparticle distribution using a gadolinium-dendron modified nano-liposomal contrast agent with magnetic resonance micro-imaging. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 29626524	2018
Metabolic and Physiologic Imaging Biomarkers of the Tumor Microenvironment Predict Treatment Outcome with Radiation or a Hypoxia-Activated Prodrug in Mice. Cancer research\| PubMed ID: 29792309	2018
Using the QCM Biosensor-Based T7 Phage Display Combined with Bioinformatics Analysis for Target Identification of Bioactive Small Molecule. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29846927	2018
Design strategy for serine hydroxymethyltransferase probes based on retro-aldol-type reaction. Nature communications\| PubMed ID: 30787298	2019
Design of Nuclear Magnetic Resonance Molecular Probes for Hyperpolarized Bioimaging. Angewandte Chemie (International ed. in English)\| PubMed ID: 32372551	2020
Continuous monitoring of postirradiation reoxygenation and cycling hypoxia using electron paramagnetic resonance imaging. NMR in biomedicine\| PubMed ID: 35661282	2022
Editorial: Phage display: Technique and applications. Frontiers in microbiology\| PubMed ID: 36560941	2022
EPR and Related Magnetic Resonance Imaging Techniques in Cancer Research. Metabolites\| PubMed ID: 36676994	2023
Activation of oxidoreductases by the formation of enzyme assembly. Scientific reports\| PubMed ID: 37658129	2023
Whole-Body and Whole-Organ 3D Imaging of Hypoxia Using an Activatable Covalent Fluorescent Probe Compatible with Tissue Clearing. ACS nano\| PubMed ID: 38301048	2024
Pimonidazole-alkyne conjugate for sensitive detection of hypoxia by Cu-catalyzed click reaction. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry\| PubMed ID: 38478357	2024
Click3D: Click reaction across deep tissues for whole-organ 3D fluorescence imaging. Science advances\| PubMed ID: 39018410	2024
Directly monitoring the dynamic in vivo metabolisms of hyperpolarized C-oligopeptides. Science advances\| PubMed ID: 39413185	2024
Quantum life science: biological nano quantum sensors, quantum technology-based hyperpolarized MRI/NMR, quantum biology, and quantum biotechnology. Chemical Society reviews\| PubMed ID: 39874046	2025
Awake brain MRSI reveals anesthetic sensitivity and regional aging effects on [C]bicarbonate metabolism in mice. Frontiers in neuroimaging\| PubMed ID: 40017822	2025
Hyperpolarized [1-C]pyruvate NMR spectroscopy reveals transition of tumor energy metabolism in microscale multicellular spheroids. Scientific reports\| PubMed ID: 40456829	2025