Lukasz Opalinski

The molecular basis of RhoA specificity in the guanine nucleotide exchange factor PDZ-RhoGEF.

The autoinhibitory function of D1 domain of FGFR1 goes beyond the inhibition of ligand binding.

Antibody-induced dimerization of FGFR1 promotes receptor endocytosis independently of its kinase activity.

High Affinity Promotes Internalization of Engineered Antibodies Targeting FGFR1.

FGF2 Dual Warhead Conjugate with Monomethyl Auristatin E and α-Amanitin Displays a Cytotoxic Effect towards Cancer Cells Overproducing FGF Receptor 1.

Targeting Cellular Trafficking of Fibroblast Growth Factor Receptors as a Strategy for Selective Cancer Treatment.

Crosstalk between p38 and Erk 1/2 in Downregulation of FGF1-Induced Signaling.

Cross-Talk between Fibroblast Growth Factor Receptors and Other Cell Surface Proteins.

Differential regulation of fibroblast growth factor receptor 1 trafficking and function by extracellular galectins.

Low Stability of Integrin-Binding Deficient Mutant of FGF1 Restricts Its Biological Activity.

FHF1 is a bona fide fibroblast growth factor that activates cellular signaling in FGFR-dependent manner.

FGFR1 clustering with engineered tetravalent antibody improves the efficiency and modifies the mechanism of receptor internalization.

Stable Fibroblast Growth Factor 2 Dimers with High Pro-Survival and Mitogenic Potential.

FGF2-Derived PeptibodyF2-MMAE Conjugate for Targeted Delivery of Cytotoxic Drugs into Cancer Cells Overexpressing FGFR1.