Department of Cardiovascular and Renal Research
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Cyclooxygenase-2 contributes to elevated renin in the early postnatal period in rats.
American journal of physiology. Regulatory, integrative and comparative physiology May, 2003 | Pubmed ID: 12560203
Low endogenous glucocorticoid allows induction of kidney cortical cyclooxygenase-2 during postnatal rat development.
American journal of physiology. Renal physiology Jan, 2004 | Pubmed ID: 13129852
Cycloxygenase-2 is expressed in vasculature of normal and ischemic adult human kidney and is colocalized with vascular prostaglandin E2 EP4 receptors.
Journal of the American Society of Nephrology : JASN May, 2004 | Pubmed ID: 15100359
Prostaglandin E2 EP2 and EP4 receptor activation mediates cAMP-dependent hyperpolarization and exocytosis of renin in juxtaglomerular cells.
American journal of physiology. Renal physiology Nov, 2005 | Pubmed ID: 15985651
Glucocorticoid impairs growth of kidney outer medulla and accelerates loop of Henle differentiation and urinary concentrating capacity in rat kidney development.
American journal of physiology. Renal physiology Oct, 2006 | Pubmed ID: 16638911
Postnatal adrenalectomy impairs urinary concentrating ability by increased COX-2 and leads to renal medullary injury.
American journal of physiology. Renal physiology Sep, 2007 | Pubmed ID: 17581922
Plasmin in nephrotic urine activates the epithelial sodium channel.
Journal of the American Society of Nephrology : JASN Feb, 2009 | Pubmed ID: 19073825
Prostaglandin F2alpha elevates blood pressure and promotes atherosclerosis.
Proceedings of the National Academy of Sciences of the United States of America May, 2009 | Pubmed ID: 19416858
Niacin and biosynthesis of PGD₂by platelet COX-1 in mice and humans.
The Journal of clinical investigation Apr, 2012 | Pubmed ID: 22406532
Regulation of renin secretion by renal juxtaglomerular cells.
Pflugers Archiv : European journal of physiology Jan, 2013 | Pubmed ID: 22733355
Ulcerating and stenosing enteropathy treated with misoprostol: a case report with analysis of prostaglandin metabolism.
European journal of gastroenterology & hepatology Oct, 2012 | Pubmed ID: 22786573
Cardiovascular inflammation.
Mediators of inflammation , 2013 | Pubmed ID: 23983400
Prostaglandin I2 and prostaglandin E2 modulate human intrarenal artery contractility through prostaglandin E2-EP4, prostacyclin-IP, and thromboxane A2-TP receptors.
Hypertension (Dallas, Tex. : 1979) Sep, 2014 | Pubmed ID: 24914192
The water channel aquaporin-1 contributes to renin cell recruitment during chronic stimulation of renin production.
American journal of physiology. Renal physiology Dec, 2014 | Pubmed ID: 25339696
MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation.
Arteriosclerosis, thrombosis, and vascular biology Jan, 2016 | Pubmed ID: 26564819
Induction of autoimmune abdominal aortic aneurysm in pigs - A novel large animal model.
Annals of medicine and surgery (2012) Aug, 2017 | Pubmed ID: 28702183
Identification of differential gene expression patterns in human arteries from patients with chronic kidney disease.
American journal of physiology. Renal physiology 06, 2018 | Pubmed ID: 29412699
Abdominal Aortic Aneurysms Growth Is Associated With High Concentrations of Plasma Proteins in the Intraluminal Thrombus and Diseased Arterial Tissue.
Arteriosclerosis, thrombosis, and vascular biology 09, 2018 | Pubmed ID: 30002058
Experimental comparative study of thrombogenicity of two differently luminal heparinized ePTFE vascular prosthetics.
Annals of medicine and surgery (2012) Nov, 2018 | Pubmed ID: 30294434
Effect of spironolactone for 1 yr on endothelial function and vascular inflammation biomarkers in renal transplant recipients.
American journal of physiology. Renal physiology 09, 2019 | Pubmed ID: 31166706
TNF deficiency causes alterations in the spatial organization of neurogenic zones and alters the number of microglia and neurons in the cerebral cortex.
Brain, behavior, and immunity 11, 2019 | Pubmed ID: 31505254
Nephrotic syndrome is associated with increased plasma K concentration, intestinal K losses and attenuated urinary K excretion - studies in rats and humans.
American journal of physiology. Renal physiology Sep, 2019 | Pubmed ID: 31566427
Conditional Ablation of Myeloid TNF Improves Functional Outcome and Decreases Lesion Size after Spinal Cord Injury in Mice.
Cells 11, 2020 | Pubmed ID: 33153044
Ulrika Dahlqvist1,
Tajana Tesan Tomic2,
Magnus Söderberg3,
Jane Stubbe4,
Camilla Enggaard4,
Anette Ericsson5,
Alex-Xianghua Zhou1,
Anna Björnson Granqvist1,
Lena William-Olsson1
1Bioscience Renal, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D,
2Cell/mol Pharmacology, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D,
3CVRM Safety, Safety, Clinical Pharmacology & Safety Sciences, R&D,
4Department of Cardiovascular and Renal Research, University of Southern Denmark,
5Clinical Renal, Late-stage Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D
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