Howard S. Fox

Decreased neuronal autophagy in HIV dementia: a mechanism of indirect neurotoxicity.

Cerebrospinal fluid proteomics reveals potential pathogenic changes in the brains of SIV-infected monkeys.

Defining larger roles for "tiny" RNA molecules: role of miRNAs in neurodegeneration research.

An integrated systems analysis implicates EGR1 downregulation in simian immunodeficiency virus encephalitis-induced neural dysfunction.

A coat of many colors: neuroimmune crosstalk in human immunodeficiency virus infection.

Quantitative plasma proteomic profiling identifies the vitamin E binding protein afamin as a potential pathogenic factor in SIV induced CNS disease.

Advances in the "omics" for diagnosis, pathogenesis, and therapeutic development.

Proteomic and metabolomic strategies to investigate HIV-associated neurocognitive disorders.

Plasma proteomic analysis of simian immunodeficiency virus infection of rhesus macaques.

Short communication: quantitative proteomic plasma profiling reveals activation of host defense to oxidative stress in chronic SIV and methamphetamine comorbidity.

Epithelial progenitor 1, a novel factor associated with epithelial cell growth and differentiation.

Pulsed stable isotope labeling of amino acids in cell culture uncovers the dynamic interactions between HIV-1 and the monocyte-derived macrophage.

Upregulation of cathepsin D in the caudate nucleus of primates with experimental parkinsonism.

Changes in the plasma proteome follows chronic opiate administration in simian immunodeficiency virus infected rhesus macaques.

Proteasome activity and autophagosome content in liver are reciprocally regulated by ethanol treatment.

Translating the brain transcriptome in neuroAIDS: from non-human primates to humans.

Commentary: Animal models of neuroAIDS.

Comparison of 4-plex to 8-plex iTRAQ quantitative measurements of proteins in human plasma samples.

Methamphetamine and inflammatory cytokines increase neuronal Na+/K+-ATPase isoform 3: relevance for HIV associated neurocognitive disorders.

Protective role for the disulfide isomerase PDIA3 in methamphetamine neurotoxicity.

The National NeuroAIDS Tissue Consortium brain gene array: two types of HIV-associated neurocognitive impairment.

N-methyl-D-aspartate receptor-mediated axonal injury in adult rat corpus callosum.

Methamphetamine administration targets multiple immune subsets and induces phenotypic alterations suggestive of immunosuppression.

Preclinical pharmacokinetics and tissue distribution of long-acting nanoformulated antiretroviral therapy.

Functional brain abnormalities during finger-tapping in HIV-infected older adults: a magnetoencephalography study.

Up-regulation of microRNA-142 in simian immunodeficiency virus encephalitis leads to repression of sirtuin1.

Transcriptome meta-analysis reveals a central role for sex steroids in the degeneration of hippocampal neurons in Alzheimer's disease.

Abnormal MEG oscillatory activity during visual processing in the prefrontal cortices and frontal eye-fields of the aging HIV brain.

Pilot study of younger and older HIV-infected adults using traditional and novel functional assessments.

Autophagy-mediated turnover of dynamin-related protein 1.

Quantitative proteomics reveals oxygen-dependent changes in neuronal mitochondria affecting function and sensitivity to rotenone.

Combined fluorescent in situ hybridization for detection of microRNAs and immunofluorescent labeling for cell-type markers.

MicroRNA-142 reduces monoamine oxidase A expression and activity in neuronal cells by downregulating SIRT1.

Biomarkers for NeuroAIDS: recent progress in the field.

Decreased MEG beta oscillations in HIV-infected older adults during the resting state.

Quantitative proteomics by SWATH-MS reveals altered expression of nucleic acid binding and regulatory proteins in HIV-1-infected macrophages.

The 20th scientific conference of the Society on NeuroImmune Pharmacology.

Quantitative proteomics of synaptic and nonsynaptic mitochondria: insights for synaptic mitochondrial vulnerability.

Cellular Interactions and Signaling in neuroAIDS: Emerging Issues Colloquium.

Aging synaptic mitochondria exhibit dynamic proteomic changes while maintaining bioenergetic function.

CD8+ T cells maintain suppression of simian immunodeficiency virus in the central nervous system.

Proteomic analysis of the mitochondria from embryonic and postnatal rat brains reveals response to developmental changes in energy demands.

Efavirenz induces neuronal autophagy and mitochondrial alterations.

Pharmacokinetics, biodistribution, and toxicity of folic acid-coated antiretroviral nanoformulations.

Enhanced methamphetamine metabolism in rhesus macaque as compared with human: an analysis using a novel method of liquid chromatography with tandem mass spectrometry, kinetic study, and substrate docking.

A new rhesus macaque assembly and annotation for next-generation sequencing analyses.

Multimodal neuroimaging evidence of alterations in cortical structure and function in HIV-infected older adults.

Early Expression of Parkinson's Disease-Related Mitochondrial Abnormalities in PINK1 Knockout Rats.

Brain region mapping using global metabolomics.

Osteopontin expression in the brain triggers localized inflammation and cell death when immune cells are activated by pertussis toxin.

Proteomic analysis and functional characterization of mouse brain mitochondria during aging reveal alterations in energy metabolism.

Chronic SIV and morphine treatment increases heat shock protein 5 expression at the synapse.

MiR-21 in Extracellular Vesicles Leads to Neurotoxicity via TLR7 Signaling in SIV Neurological Disease.

Data for mitochondrial proteomic alterations in the developing rat brain.

Data for mitochondrial proteomic alterations in the aging mouse brain.

The National NeuroAIDS Tissue Consortium (NNTC) Database: an integrated database for HIV-related studies.

Phenotypic changes in the brain of SIV-infected macaques exposed to methamphetamine parallel macrophage activation patterns induced by the common gamma-chain cytokine system.

Coexpression Network Analysis of miRNA-142 Overexpression in Neuronal Cells.

Acute and Chronic Ethanol Administration Differentially Modulate Hepatic Autophagy and Transcription Factor EB.

The Proteomic Characterization of Plasma or Serum from HIV-Infected Patients.

HIV-1 transgenic rats display mitochondrial abnormalities consistent with abnormal energy generation and distribution.

Neonatal mitochondrial abnormalities due to PINK1 deficiency: Proteomics reveals early changes relevant to Parkinson׳s disease.

Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA.

Methamphetamine abuse affects gene expression in brain-derived microglia of SIV-infected macaques to enhance inflammation and promote virus targets.

Metabolic drift in the aging brain.

Traumatic brain injury increases levels of miR-21 in extracellular vesicles: implications for neuroinflammation.

Loss of Pink1 modulates synaptic mitochondrial bioenergetics in the rat striatum prior to motor symptoms: concomitant complex I respiratory defects and increased complex II-mediated respiration.

SWATH-MS proteome profiling data comparison of DJ-1, Parkin, and PINK1 knockout rat striatal mitochondria.

Emerging roles of extracellular vesicles in neurodegenerative disorders: focus on HIV-associated neurological complications.

Aberrant Neuronal Dynamics during Working Memory Operations in the Aging HIV-Infected Brain.

Tat-Mediated Induction of miRs-34a & -138 Promotes Astrocytic Activation via Downregulation of SIRT1: Implications for Aging in HAND.

Measures of Physical and Mental Independence Among HIV-Positive Individuals: Impact of Substance Use Disorder.

Induction of miR-155 after Brain Injury Promotes Type 1 Interferon and has a Neuroprotective Effect.

Osteopontin Impacts Pathogenesis and Resistance by Regulating Inflammasome Components and Cell Death in the Central Nervous System at Early Time Points.

Central nervous system-penetrating antiretrovirals impair energetic reserve in striatal nerve terminals.

Creation of a nanoformulated cabotegravir prodrug with improved antiretroviral profiles.

Pharmacokinetics of a Long-Acting Nanoformulated Dolutegravir Prodrug in Rhesus Macaques.

Sirtuin 1-Chromatin-Binding Dynamics Points to a Common Mechanism Regulating Inflammatory Targets in SIV Infection and in the Aging Brain.

Multimodal Theranostic Nanoformulations Permit Magnetic Resonance Bioimaging of Antiretroviral Drug Particle Tissue-Cell Biodistribution.

Aberrant occipital dynamics differentiate HIV-infected patients with and without cognitive impairment.

Molecular mechanisms of long noncoding RNAs and their role in disease pathogenesis.

Aberrant oscillatory dynamics during somatosensory processing in HIV-infected adults.

Proteomic and functional data sets on synaptic mitochondria from rats with genetic ablation of .

Pharmacokinetic testing of a first-generation cabotegravir prodrug in rhesus macaques.

Neural dynamics of selective attention deficits in HIV-associated neurocognitive disorder.

The integrated National NeuroAIDS Tissue Consortium database: a rich platform for neuroHIV research.

A mouse model of seizures in anti-N-methyl-d-aspartate receptor encephalitis.

Quantitative Proteomics of Presynaptic Mitochondria Reveal an Overexpression and Biological Relevance of Neuronal MitoNEET in Postnatal Brain Development.

Downregulation of an Evolutionary Young miR-1290 in an iPSC-Derived Neural Stem Cell Model of Autism Spectrum Disorder.

Secreted Metabolome of Human Macrophages Exposed to Methamphetamine.

Creation of a long-acting rilpivirine prodrug nanoformulation.

Epigenetic Markers of Aging Predict the Neural Oscillations Serving Selective Attention.

Defining cerebrospinal fluid HIV RNA escape: editorial review AIDS.

Age-related visual dynamics in HIV-infected adults with cognitive impairment.

Interactive effects of HIV and ageing on neural oscillations: independence from neuropsychological performance.

A year-long extended release nanoformulated cabotegravir prodrug.

HIV-1 Tat-mediated astrocytic amyloidosis involves the HIF-1α/lncRNA BACE1-AS axis.

Interactions of Monocytes, HIV, and ART Identified by an Innovative scRNAseq Pipeline: Pathways to Reservoirs and HIV-Associated Comorbidities.

Deletion of DJ-1 in rats affects protein abundance and mitochondrial function at the synapse.

Pathogenesis of Aging and Age-related Comorbidities in People with HIV: Highlights from the HIV ACTION Workshop.

Association of Epigenetic Metrics of Biological Age With Cortical Thickness.

Prefrontal gating of sensory input differentiates cognitively impaired and unimpaired aging adults with HIV.

Pharmacologic approaches to HIV-associated neurocognitive disorders.

The age-related trajectory of visual attention neural function is altered in adults living with HIV: A cross-sectional MEG study.

Methamphetamine Increases the Proportion of SIV-Infected Microglia/Macrophages, Alters Metabolic Pathways, and Elevates Cell Death Pathways: A Single-Cell Analysis.

Chronic morphine administration differentially modulates viral reservoirs in SIVmac251 infected rhesus macaque model.