a-mouse-model-for-chronic-pancreatitis-via-bile-duct-tnbs-infusion

A Mouse Model for Chronic Pancreatitis via Bile Duct TNBS Infusion

Chronic pancreatitis (CP) is a complex disease involving pancreatic inflammation and fibrosis, glandular atrophy, abdominal pain and other symptoms. ...

Medical University of South Carolina

Ralph H. Johnson Veterans Affairs Medical Center

Osteoradionecrosis of the mandible is a debilitating consequence of radiation therapy for head-and-neck malignancy. It can result in pain, bone exposure, fistula formation, and pathologic fracture. Recombinant human bone morphogenetic protein 2 (rhBMP-2) has shown promise in reconstruction of bone defects. The purpose of this study is to determine whether the addition of rhBMP-2 at the union of vascularized bone and native bone improves surgical outcomes in patients with osteonecrosis of the mandible.

Use of recombinant bone morphogenetic protein 2 in free flap reconstruction for osteonecrosis of the mandible.

There is increasing interest in implementing comprehensive perioperative protocols, including preoperative optimization and education, perioperative goal-directed fluid management, and postoperative fast tracking, to enhance recovery after surgery. Data on the outcomes of these protocols in pancreatic surgery, however, are limited.

Enhanced Recovery After Surgery Protocols Are Valuable in Pancreas Surgery Patients.

Best practice to select patients with chronic pancreatitis for surgical management with total pancreatectomy with islet autotransplantation (TPIAT) is in evolution as new discoveries are made in the pathogenesis of chronic pancreatitis.

Patient Selection for Total Pancreatectomy with Islet Autotransplantation in the Surgical Management of Chronic Pancreatitis.

Indications for sentinel lymph node (SLN) biopsy in the population with thin melanoma have frequently changed over time. The objective of our study was to evaluate T1 melanoma pathologic features predictive of SLN positivity with a primary focus on identifying a specific mitotic value that is most predictive of lymph node disease. Further detailed predictive features would help physicians select patients with thin melanoma for SLN biopsy.

High Mitotic Rate Predicts Sentinel Lymph Node Involvement in Thin Melanomas.

Although volume-outcome literature supports regionalization for complex procedures, travel may be burdensome. We assessed the relationship between overall survival and travel distance for patients undergoing pancreatic resection for adenocarcinoma.

Travel distance and its interaction with patient and hospital factors in pancreas cancer care.

Our objective was to assess the relationship between overall survival (OS) and distance travelled to the treating facility for patients undergoing liver resection for hepatocellular carcinoma and to determine whether this relationship was dependent upon the structural factors of the treating facility.

Article	Year
Use of recombinant bone morphogenetic protein 2 in free flap reconstruction for osteonecrosis of the mandible. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons\| PubMed ID: 22177824
Enhanced Recovery After Surgery Protocols Are Valuable in Pancreas Surgery Patients. Journal of the American College of Surgeons\| PubMed ID: 26916130
Patient Selection for Total Pancreatectomy with Islet Autotransplantation in the Surgical Management of Chronic Pancreatitis. Journal of the American College of Surgeons\| PubMed ID: 29289751
High Mitotic Rate Predicts Sentinel Lymph Node Involvement in Thin Melanomas. The Journal of surgical research\| PubMed ID: 32711176
Travel distance and its interaction with patient and hospital factors in pancreas cancer care. American journal of surgery\| PubMed ID: 32891396
Travel distance and overall survival in hepatocellular cancer care. American journal of surgery\| PubMed ID: 33413878	2020

William P. Lancaster

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