Diogo O. Souza

Serum S100B levels in patients with lupus erythematosus: preliminary observation.

Quinolinic acid stimulates synaptosomal glutamate release and inhibits glutamate uptake into astrocytes.

Utilization of energy nutrients by cerebellar slices.

Intrahippocampal infusion of ebselen impairs retention of an inhibitory avoidance task in rats.

The adenosine antagonist theophylline impairs p50 auditory sensory gating in normal subjects.

Effect of undernutrition on GMP-PNP binding and adenylate cyclase activity from rat brain.

Methylmercury inhibits glutamate uptake by synaptic vesicles from rat brain.

Effects of undernutrition on glutamatergic parameters in rat brain.

Neuroprotective effect of ebselen on rat hippocampal slices submitted to oxygen-glucose deprivation: correlation with immunocontent of inducible nitric oxide synthase.

Ebselen protects against methylmercury-induced inhibition of glutamate uptake by cortical slices from adult mice.

Diphenyl diselenide protects rat hippocampal slices submitted to oxygen-glucose deprivation and diminishes inducible nitric oxide synthase immunocontent.

Effects of L-2-hydroxyglutaric acid on various parameters of the glutamatergic system in cerebral cortex of rats.

In vitro effects of D-2-hydroxyglutaric acid on glutamate binding, uptake and release in cerebral cortex of rats.

Increase in serum S100B protein level after a swimming race.

Caffeine as a neuroprotective adenosine receptor antagonist.

Effect of DHEA glutamate release from synaptosomes of rats at different ages.

Anticonvulsant effect of GMP depends on its conversion to guanosine.

Characterization of imido [8-(3)H] guanosine 5'-triphosphate binding sites to rat brain membranes.

Ontogenetic profile of glutamate uptake in brain structures slices from rats: sensitivity to guanosine.

High extracellular K+ levels stimulate acetate oxidation in brain slices from well and malnourished rats.

Glutaric acid stimulates glutamate binding and astrocytic uptake and inhibits vesicular glutamate uptake in forebrain from young rats.

Biochemical brain markers and purinergic parameters in rat CSF after seizure induced by pentylenetetrazol.

The effects of ebselen on [3H]glutamate uptake by synaptic vesicles from rat brain.

Increased locomotor response to amphetamine, but not other psychostimulants, in adult mice submitted to a low-protein diet.

Changes in S100B cerebrospinal fluid levels of rats subjected to predator stress.

Gestational and postnatal malnutrition affects sensitivity of young rats to picrotoxin and quinolinic acid and uptake of GABA by cortical and hippocampal slices.

The ischemic rat heart releases S100B.

Cinnarizine has an atypical antipsychotic profile in animal models of psychosis.

Effects of glutamate transporter and receptor ligands on neuronal glutamate uptake.

Serum S100B levels in patients with neural tube defects.

Exercise affects glutamate receptors in postsynaptic densities from cortical mice brain.

Acute and chronic electroconvulsive shock in rats: effects on peripheral markers of neuronal injury and glial activity.

Glutamate uptake is stimulated by extracellular S100B in hippocampal astrocytes.

A simple webcam-based approach for the measurement of rodent locomotion and other behavioural parameters.

Effect of 2-deoxy-D-glucose on aminoacids metabolism in rats' cerebral cortex slices.

The sesquiterpenes polygodial and drimanial in vitro affect glutamatergic transport in rat brain.

Beta-amyloid treatment sensitizes mice to amphetamine-induced locomotion but reduces response to caffeine.

Methylmercury induces oxidative injury, alterations in permeability and glutamine transport in cultured astrocytes.

Naturally occurring compounds affect glutamatergic neurotransmission in rat brain.

Age and brain structural related effects of glutaric and 3-hydroxyglutaric acids on glutamate binding to plasma membranes during rat brain development.

Proposal of a guanine-based purinergic system in the mammalian central nervous system.

Duration of environmental enrichment influences the magnitude and persistence of its behavioral effects on mice.

Evidence that glutaric acid reduces glutamate uptake by cerebral cortex of infant rats.

Western style diet impairs entrance of blood-borne insulin-like growth factor-1 into the brain.

Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain.

Profile of glutamate uptake and cellular viability in hippocampal slices exposed to oxygen and glucose deprivation: developmental aspects and protection by guanosine.

Effects of undernutrition on glutamatergic parameters in the cerebral cortex of young rats.

Morphological changes in hippocampal astrocytes induced by environmental enrichment in mice.

Gestational and postnatal low protein diet alters insulin sensitivity in female rats.

Algorithms to predict cerebral malaria in murine models using the SHIRPA protocol.

Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity.

Structure-activity relationship of flavonoids derived from medicinal plants in preventing methylmercury-induced mitochondrial dysfunction.

Enriched environment effects on behavior, memory and BDNF in low and high exploratory mice.

Differences in spatio-temporal behavior of zebrafish in the open tank paradigm after a short-period confinement into dark and bright environments.

37 years of scientific activity in a Biochemistry Department in Brazil: patterns of growth and factors leading to increased productivity.

Motor impairment induced by oral exposure to methylmercury in adult mice.

Evidence that hyperprolinemia alters glutamatergic homeostasis in rat brain: neuroprotector effect of guanosine.

Ω3-Polyunsaturated fatty acids prevent lipoperoxidation, modulate antioxidant enzymes, and reduce lipid content but do not alter glycogen metabolism in the livers of diabetic rats fed on a high fat thermolyzed diet.

Behavioral effects of taurine pretreatment in zebrafish acutely exposed to ethanol.

AgRP neurons regulate development of dopamine neuronal plasticity and nonfood-associated behaviors.

Riluzole increases glutamate uptake by cultured C6 astroglial cells.

Topographical analysis of reactive zinc in the central nervous system of adult zebrafish (Danio rerio).

Evaluation of spontaneous recovery of behavioral and brain injury profiles in zebrafish after hypoxia.

Anxiolytic effects of diphenyl diselenide on adult zebrafish in a novelty paradigm.

Antioxidant effects of JM-20 on rat brain mitochondria and synaptosomes: mitoprotection against Ca²⁺-induced mitochondrial impairment.

The effects of JM-20 on the glutamatergic system in synaptic vesicles, synaptosomes and neural cells cultured from rat brain.

Original mechanisms of antipsychotic action by the indole alkaloid alstonine (Picralima nitida).

High phosphate serum levels correlate with the severity of experimental severe acute pancreatitis: insight into the purinergic system.

Long-term NMDAR antagonism correlates reduced astrocytic glutamate uptake with anxiety-like phenotype.

Ovotoxicants 4-vinylcyclohexene 1,2-monoepoxide and 4-vinylcyclohexene diepoxide disrupt redox status and modify different electrophile sensitive target enzymes and genes in Drosophila melanogaster.

Influence of diphenyl diselenide on chlorpyrifos-induced toxicity in Drosophila melanogaster.

Neuroprotection by JM-20 against oxygen-glucose deprivation in rat hippocampal slices: Involvement of the Akt/GSK-3β pathway.

Intranasal guanosine administration presents a wide therapeutic time window to reduce brain damage induced by permanent ischemia in rats.

Guanosine Anxiolytic-Like Effect Involves Adenosinergic and Glutamatergic Neurotransmitter Systems.

Brain zinc chelation by diethyldithiocarbamate increased the behavioral and mitochondrial damages in zebrafish subjected to hypoxia.

Neuroprotection of luteolin against methylmercury-induced toxicity in lobster cockroach Nauphoeta cinerea.

Guanosine Exerts Neuroprotective Effect in an Experimental Model of Acute Ammonia Intoxication.

Corrigendum: Long-term NMDAR antagonism correlates reduced astrocytic glutamate uptake with anxiety-like phenotype.

Neurobehavioral and biochemical changes in Nauphoeta cinerea following dietary exposure to chlorpyrifos.

Antimicrobial Activity and Modulatory Effect of Essential Oil from the Leaf of Rhaphiodon echinus (Nees & Mart) Schauer on Some Antimicrobial Drugs.

Scientific Performance of Brazilian Researchers in Pharmacology with grants from CNPq: A comparative study within the Brazilian categories.

How does zebrafish support new strategies for neuroprotection and neuroregeneration in hypoxia-related diseases?

ZIKA Virus and Neuroscience: the Need for a Translational Collaboration.

Olfactory bulbectomy in mice triggers transient and long-lasting behavioral impairments and biochemical hippocampal disturbances.

Cortical Bilateral Adaptations in Rats Submitted to Focal Cerebral Ischemia: Emphasis on Glial Metabolism.

Mitochondrial involvement in memory impairment induced by scopolamine in rats.

Evaluation of zinc effect on cadmium action in lipid peroxidation and metallothionein levels in the brain.

Antioxidant and Neuroprotective Effects of KM-34, A Novel Synthetic Catechol, Against Oxidative Stress-Induced Neurotoxicity.

JM-20 Treatment After MCAO Reduced Astrocyte Reactivity and Neuronal Death on Peri-infarct Regions of the Rat Brain.

Multi-targeting effects of a new synthetic molecule (JM-20) in experimental models of cerebral ischemia.

Dietary co-exposure to methylmercury and monosodium glutamate disrupts cellular and behavioral responses in the lobster cockroach, Nauphoeta cinerea model.

Zika Virus Infection of Human Mesenchymal Stem Cells Promotes Differential Expression of Proteins Linked to Several Neurological Diseases.

Memantine mediates astrocytic activity in response to excitotoxicity induced by PP2A inhibition.

Behavioral, Neurochemical and Brain Oscillation Abnormalities in an Experimental Model of Acute Liver Failure.

Caffeine and cannabinoid receptors modulate impulsive behavior in an animal model of attentional deficit and hyperactivity disorder.

The astrocyte biochemistry.

ZIKAVID-Zika virus infection database: a new platform to analyze the molecular impact of Zika virus infection.

Association between Zika virus and future neurological diseases.

Acute Liver Failure Induces Glial Reactivity, Oxidative Stress and Impairs Brain Energy Metabolism in Rats.

Modified expression of antioxidant genes in lobster cockroach, Nauphoeta cinerea exposed to methylmercury and monosodium glutamate.

Amyloid-β oligomers in cellular models of Alzheimer's disease.

Guanosine fast onset antidepressant-like effects in the olfactory bulbectomy mice model.

S100B protein and neuron-specific enolase as predictors of postoperative cognitive dysfunction in aged dogs: a case-control study.

Guanosine enhances glutamate uptake and oxidation, preventing oxidative stress in mouse hippocampal slices submitted to high glutamate levels.

Dietary omega-3 fatty acids prevent neonatal seizure-induced early alterations in the hippocampal glutamatergic system and memory deficits in adulthood.

PET Imaging as a Tool for Assessing COVID-19 Brain Changes.

Novel arylidene malonate derivative, KM-34, showed neuroprotective effects on in vitro and in vivo models of ischemia/reperfusion.

About the source and consequences of F-FDG brain PET hypometabolism in short and long COVID-19.

Effects of intranasal guanosine administration on brain function in a rat model of ischemic stroke.

Allopurinol for fibromyalgia pain in adults: A randomized controlled trial.

Zika Virus Infection Associated with Autism Spectrum Disorder: A Case Report.

Allopurinol attenuates postoperative pain and modulates the purinergic system in patients undergoing abdominal hysterectomy: a randomized controlled trial.

Antidepressant-Like Effects of Chronic Guanosine in the Olfactory Bulbectomy Mouse Model.

JM-20 treatment prevents neuronal damage and memory impairment induced by aluminum chloride in rats.