Suzanne Scarlata

Determination of strength and specificity of membrane-bound G protein--phospholipase C association using fluorescence spectroscopy.

Regulation of the lateral association of phospholipase Cbeta2 and G protein subunits by lipid rafts.

Role of dynamic interactions in effective signal transfer for Gbeta stimulation of phospholipase C-beta 2.

Multiple roles of pleckstrin homology domains in phospholipase Cbeta function.

The Pleckstrin homology domains of phospholipases C-beta and -delta confer activation through a common site.

Role of myristylation in HIV-1 Gag assembly.

Role of HIV-1 Gag domains in viral assembly.

The pH dependence of HIV-1 capsid assembly and its interaction with cyclophilin A.

The use of green fluorescent proteins to view association between phospholipase C beta and G protein subunits in cells.

N-terminal myristoylation regulates calcium-induced conformational changes in neuronal calcium sensor-1.

Influence of membrane components in the binding of proteins to membrane surfaces.

Phospholipase Cbeta2 binds to and inhibits phospholipase Cdelta1.

The cysteine residues of HIV-1 capsid regulate oligomerization and cyclophilin A-induced changes.

Fluorescence studies suggest a role for alpha-synuclein in the phosphatidylinositol lipid signaling pathway.

Determination of the activation volume of PLCbeta by Gbeta gamma-subunits through the use of high hydrostatic pressure.

Dissection of the steps of phospholipase C beta 2 activity that are enhanced by G beta gamma subunits.

Cloning and characterization of a phospholipase C-beta isoform from the sea urchin Lytechinus pictus.

Galphaq binds to p110alpha/p85alpha phosphoinositide 3-kinase and displaces Ras.

The pleckstrin homology domain of phospholipase Cbeta transmits enzymatic activation through modulation of the membrane-domain orientation.

Stable association between G alpha(q) and phospholipase C beta 1 in living cells.

Real-time measurements of protein affinities on membrane surfaces by fluorescence spectroscopy.

Signaling through a G Protein-coupled receptor and its corresponding G protein follows a stoichiometrically limited model.

Stimulation of phospholipase Cbeta by membrane interactions, interdomain movement, and G protein binding--how many ways can you activate an enzyme?

A novel empirical free energy function that explains and predicts protein-protein binding affinities.

Caveolin-1 alters Ca(2+) signal duration through specific interaction with the G alpha q family of G proteins.

Galphaq binds two effectors separately in cells: evidence for predetermined signaling pathways.

Fluorescence approaches to quantifying biomolecular interactions.

Expression and function of phospholipase C in breast carcinoma.

A self-scaffolding model for G protein signaling.

Evidence for a second, high affinity Gbetagamma binding site on Galphai1(GDP) subunits.

Novel endogenous peptide agonists of cannabinoid receptors.

Evidence for convergent evolution in the signaling properties of a choanoflagellate tyrosine kinase.

The effect of membrane domains on the G protein-phospholipase Cbeta signaling pathway.

The differential affinity of the usher for chaperone-subunit complexes is required for assembly of complete pili.

The small G protein Rac1 activates phospholipase Cdelta1 through phospholipase Cbeta2.

Identification of a novel binding partner of phospholipase cβ1: translin-associated factor X.

Protein kinase C phosphorylation of PLCβ1 regulates its cellular localization.

Differential response to morphine of the oligomeric state of μ-opioid in the presence of δ-opioid receptors.

Modulation of Ca²+ activity in cardiomyocytes through caveolae-Gαq interactions.

A dynamic model of membrane-bound phospholipase Cβ2 activation by Gβγ subunits.

Evidence for a fence that impedes the diffusion of phosphatidylinositol 4,5-bisphosphate out of the forming phagosomes of macrophages.

The correlation between multidomain enzymes and multiple activation mechanisms--the case of phospholipase Cβ and its membrane interactions.

α-synuclein increases the cellular level of phospholipase Cβ1.