Department of Experimental and Clinical Medicine,
Section of Internal Medicine,
Department of Experimental and Clinical Medicine, Section of Internal Medicine
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A HERG current sustains a cardiac-type action potential in neuroblastoma S cells.
Biochemical and biophysical research communications Feb, 2003 | Pubmed ID: 12593854
hERG1 channels in human esophagus: evidence for their aberrant expression in the malignant progression of Barrett's esophagus.
Journal of cellular physiology Nov, 2006 | Pubmed ID: 16883575
Identification of a posttranslational mechanism for the regulation of hERG1 K+ channel expression and hERG1 current density in tumor cells.
Molecular and cellular biology Aug, 2008 | Pubmed ID: 18559421
hLH/hCG-receptor expression correlates with in vitro invasiveness in human primary endometrial cancer.
Gynecologic oncology Dec, 2008 | Pubmed ID: 18829089
Integrin structure and functional relation with ion channels.
Advances in experimental medicine and biology , 2010 | Pubmed ID: 20549935
Optical methods in the study of protein-protein interactions.
Advances in experimental medicine and biology , 2010 | Pubmed ID: 20549938
Physical and functional interaction between integrins and hERG1 channels in cancer cells.
Advances in experimental medicine and biology , 2010 | Pubmed ID: 20549940
Irresponsiveness of two retinoblastoma cases to conservative therapy correlates with up- regulation of hERG1 channels and of the VEGF-A pathway.
BMC cancer , 2010 | Pubmed ID: 20860824
Deterministic and stochastic aspects of VEGF-A production and the cooperative behavior of tumoral cell colony.
Journal of theoretical biology Mar, 2011 | Pubmed ID: 21167179
hERG1 Channels and Glut-1 as Independent Prognostic Indicators of Worse Outcome in Stage I and II Colorectal Cancer: A Pilot Study.
Translational oncology Apr, 2012 | Pubmed ID: 22496927
Immunohistochemical biomarkers in gastric cancer research and management.
International journal of surgical oncology , 2012 | Pubmed ID: 22778942
High hERG1 expression in advanced melanoma.
Melanoma research Jun, 2013 | Pubmed ID: 23524483
Advances in lipid-based platforms for RNAi therapeutics.
Journal of medicinal chemistry Feb, 2014 | Pubmed ID: 24047101
An analytical method for the quantification of hERG1 channel gene expression in human colorectal cancer.
Diagnostic molecular pathology : the American journal of surgical pathology, part B Dec, 2013 | Pubmed ID: 24193004
hERG1 channels modulate integrin signaling to trigger angiogenesis and tumor progression in colorectal cancer.
Scientific reports Nov, 2013 | Pubmed ID: 24270902
Over-Expression of the LH Receptor Increases Distant Metastases in an Endometrial Cancer Mouse Model.
Frontiers in oncology , 2013 | Pubmed ID: 24312898
Development of novel anti-Kv 11.1 antibody-conjugated PEG-TiO nanoparticles for targeting pancreatic ductal adenocarcinoma cells.
Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology , 2013 | Pubmed ID: 24348091
Searching for protein binding sites from Molecular Dynamics simulations and paramagnetic fragment-based NMR studies.
Biochimica et biophysica acta Mar, 2014 | Pubmed ID: 24373878
Characterization of hERG1 channel role in mouse colorectal carcinogenesis.
Cancer medicine Oct, 2013 | Pubmed ID: 24403225
hERG1 channels regulate VEGF-A secretion in human gastric cancer: clinicopathological correlations and therapeutical implications.
Clinical cancer research : an official journal of the American Association for Cancer Research Mar, 2014 | Pubmed ID: 24449824
Interaction of tumour cells with their microenvironment: ion channels and cell adhesion molecules. A focus on pancreatic cancer.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences Mar, 2014 | Pubmed ID: 24493749
Time resolved SAXS to study the complexation of siRNA with cationic micelles of divalent surfactants.
Soft matter Apr, 2014 | Pubmed ID: 24651873
VEGF-A clinical significance in gastric cancers: immunohistochemical analysis of a wide Italian cohort.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology Oct, 2014 | Pubmed ID: 24784776
NAMI-A is highly cytotoxic toward leukaemia cell lines: evidence of inhibition of KCa 3.1 channels.
Dalton transactions (Cambridge, England : 2003) Aug, 2014 | Pubmed ID: 24975719
New pyrimido-indole compound CD-160130 preferentially inhibits the KV11.1B isoform and produces antileukemic effects without cardiotoxicity.
Molecular pharmacology Feb, 2015 | Pubmed ID: 25411366
Ion channel expression as promising cancer biomarker.
Biochimica et biophysica acta Oct, 2015 | Pubmed ID: 25542783
Lymphatic endothelial progenitor cells and vascular endothelial growth factor-C in spondyloarthritis and Crohn's disease: two overlapping diseases?
Clinical and experimental rheumatology Mar-Apr, 2015 | Pubmed ID: 25664492
Design, synthesis and characterisation of new chimeric ruthenium(II)-gold(I) complexes as improved cytotoxic agents.
Dalton transactions (Cambridge, England : 2003) Jun, 2015 | Pubmed ID: 25996553
Novel perspectives in cancer therapy: Targeting ion channels.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy Jul-Aug, 2015 | Pubmed ID: 26183291
cis-Pt I2(NH3)2: a reappraisal.
Dalton transactions (Cambridge, England : 2003) Sep, 2015 | Pubmed ID: 26226326
hERG1 Potassium Channels: Novel Biomarkers in Human Solid Cancers.
BioMed research international , 2015 | Pubmed ID: 26339650
Tumor-selective peptide-carrier delivery of Paclitaxel increases in vivo activity of the drug.
Scientific reports Dec, 2015 | Pubmed ID: 26626158
Cisplatin and its dibromido analogue: a comparison of chemical and biological profiles.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 06, 2016 | Pubmed ID: 27086032
hERG1 behaves as biomarker of progression to adenocarcinoma in Barrett's esophagus and can be exploited for a novel endoscopic surveillance.
Oncotarget Sep, 2016 | Pubmed ID: 27517748
LH/hCG-Receptor Expression May Have a Negative Prognostic Value in Low-Risk Endometrial Cancer.
Frontiers in oncology , 2016 | Pubmed ID: 27610354
New Trends in Cancer Therapy: Targeting Ion Channels and Transporters.
Pharmaceuticals (Basel, Switzerland) Apr, 2010 | Pubmed ID: 27713296
hERG1 positivity and Glut-1 negativity identifies high-risk TNM stage I and II colorectal cancer patients, regardless of adjuvant chemotherapy.
OncoTargets and therapy , 2016 | Pubmed ID: 27789963
hERG Channels: From Antitargets to Novel Targets for Cancer Therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research Jan, 2017 | Pubmed ID: 27903676
The conformational state of hERG1 channels determines integrin association, downstream signaling, and cancer progression.
Science signaling Apr, 2017 | Pubmed ID: 28377405
A novel microfluidic 3D platform for culturing pancreatic ductal adenocarcinoma cells: comparison with in vitro cultures and in vivo xenografts.
Scientific reports 04, 2017 | Pubmed ID: 28465513
Auranofin, EtPAuCl, and EtPAuI Are Highly Cytotoxic on Colorectal Cancer Cells: A Chemical and Biological Study.
ACS medicinal chemistry letters Oct, 2017 | Pubmed ID: 29057040
Circulating Endothelial Progenitor Cells in Type 1 Diabetic Patients: Relation with Patients' Age and Disease Duration.
Frontiers in endocrinology , 2017 | Pubmed ID: 29109697
The combined activation of K3.1 and inhibition of K11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells.
British journal of cancer 01, 2018 | Pubmed ID: 29161243
Engineering l-asparaginase for spontaneous formation of calcium phosphate bioinspired microreactors.
Physical chemistry chemical physics : PCCP May, 2018 | Pubmed ID: 29697113
Postnatal Changes in K/Cl Cotransporter-2 Expression in the Forebrain of Mice Bearing a Mutant Nicotinic Subunit Linked to Sleep-Related Epilepsy.
Neuroscience 08, 2018 | Pubmed ID: 29949744
hERG1 channel expression associates with molecular subtypes and prognosis in breast cancer.
Cancer cell international , 2018 | Pubmed ID: 30002601
Peptides and small molecules blocking the CXCR4/CXCL12 axis overcome bone marrow‑induced chemoresistance in acute leukemias.
Oncology reports Jan, 2019 | Pubmed ID: 30365110
Generation and characterization of novel recombinant anti-hERG1 scFv antibodies for cancer molecular imaging.
Oncotarget Oct, 2018 | Pubmed ID: 30405887
Ion Channel Conformations Regulate Integrin-Dependent Signaling.
Trends in cell biology 04, 2019 | Pubmed ID: 30635161
The Activity of Kv 11.1 Potassium Channel Modulates F-Actin Organization During Cell Migration of Pancreatic Ductal Adenocarcinoma Cells.
Cancers Jan, 2019 | Pubmed ID: 30678127
Replacement of the Thiosugar of Auranofin with Iodide Enhances the Anticancer Potency in a Mouse Model of Ovarian Cancer.
ACS medicinal chemistry letters Apr, 2019 | Pubmed ID: 30996813
The ion channels and transporters gene expression profile indicates a shift in excitability and metabolisms during malignant progression of Follicular Lymphoma.
Scientific reports 06, 2019 | Pubmed ID: 31197180
Data describing the effects of the Macrolide Antibiotic Clarithromycin on preclinical mouse models of Colorectal Cancer.
Data in brief Oct, 2019 | Pubmed ID: 31508470
Ion Channel Targeting with Antibodies and Antibody Fragments for Cancer Diagnosis.
Antibodies (Basel, Switzerland) May, 2019 | Pubmed ID: 31544839
hERG1 and CA IX expression are associated with disease recurrence in surgically resected clear cell renal carcinoma.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 01, 2020 | Pubmed ID: 31679954
The hERG1 Potassium Channel Behaves As Prognostic Factor In Gastric Dysplasia Endoscopic Samples.
OncoTargets and therapy , 2019 | Pubmed ID: 31807018
hERG1 and HIF-2α Behave as Biomarkers of Positive Response to Bevacizumab in Metastatic Colorectal Cancer Patients.
Translational oncology Mar, 2020 | Pubmed ID: 32105990
Clarithromycin inhibits autophagy in colorectal cancer by regulating the hERG1 potassium channel interaction with PI3K.
Cell death & disease 03, 2020 | Pubmed ID: 32123164
Proton Pump Inhibitors Reduce Pancreatic Adenocarcinoma Progression by Selectively Targeting H, K-ATPases in Pancreatic Cancer and Stellate Cells.
Cancers Mar, 2020 | Pubmed ID: 32164284
Correction: Clarithromycin inhibits autophagy in colorectal cancer by regulating the hERG1 potassium channel interaction with PI3K.
Cell death & disease Mar, 2020 | Pubmed ID: 32231201
K11.1 Potassium Channel and the Na/H Antiporter NHE1 Modulate Adhesion-Dependent Intracellular pH in Colorectal Cancer Cells.
Frontiers in pharmacology , 2020 | Pubmed ID: 32587517
Analysis of resorbable mesh implants in short-term human muscular fascia cultures: a pilot study.
Hernia : the journal of hernias and abdominal wall surgery 12, 2020 | Pubmed ID: 32725294
and mutation detection in circulating DNA from patients with metastatic colorectal cancer using BEAMing assay: Concordance with standard biopsy and clinical evaluation.
Oncology letters Jan, 2021 | Pubmed ID: 33240421
Data describing the effects of potassium channels modulators on outward currents measured in human lymphoma cell lines.
Data in brief Feb, 2021 | Pubmed ID: 33385031
Mitochondrial oxidative metabolism contributes to a cancer stem cell phenotype in cholangiocarcinoma.
Journal of hepatology 06, 2021 | Pubmed ID: 33484774
Expression and purification of a novel single-chain diabody (scDb-hERG1/β1) from Pichia pastoris transformants.
Protein expression and purification 08, 2021 | Pubmed ID: 33826963
Ion Channels Orchestrate Pancreatic Ductal Adenocarcinoma Progression and Therapy.
Frontiers in pharmacology , 2020 | Pubmed ID: 33841132
Transgenic mice overexpressing the LH receptor in the female reproductive system spontaneously develop endometrial tumour masses.
Scientific reports 04, 2021 | Pubmed ID: 33893331
Extracellular Signal-Regulated Kinase 5 Regulates the Malignant Phenotype of Cholangiocarcinoma Cells.
Hepatology (Baltimore, Md.) Oct, 2021 | Pubmed ID: 33959996
Harnessing the hERG1/β1 Integrin Complex via a Novel Bispecific Single-chain Antibody: An Effective Strategy against Solid Cancers.
Molecular cancer therapeutics 08, 2021 | Pubmed ID: 34045227
Neonatal Nav1.5 Protein Expression in Human Colorectal Cancer: Immunohistochemical Characterization and Clinical Evaluation.
Cancers Jul, 2021 | Pubmed ID: 34359733
A Transcriptomic Approach Reveals Selective Ribosomal Remodelling in the Tumour Versus the Stromal Compartment of Metastatic Colorectal Cancer.
Cancers Aug, 2021 | Pubmed ID: 34439343
Bioelectricity of Cancer.
Bioelectricity Sep, 2019 | Pubmed ID: 34471814
Circulating miRNome profiling data in Behçet's syndrome.
Data in brief Oct, 2021 | Pubmed ID: 34632024
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