Leslie Dan Faculty of Pharmacy,
Department of Mechanical and Industrial Engineering
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Structural proteomics: toward high-throughput structural biology as a tool in functional genomics.
Accounts of chemical research Mar, 2003 | Pubmed ID: 12641475
P1 Trisaccharide (Galalpha1,4Galbeta1,4GlcNAc) synthesis by enzyme glycosylation reactions using recombinant Escherichia coli.
Applied and environmental microbiology Apr, 2003 | Pubmed ID: 12676690
Nuclear hormone receptors, metabolism, and aging: what goes around comes around. Transcription factors link lipid metabolism and aging-related processes.
Science of aging knowledge environment : SAGE KE Nov, 2004 | Pubmed ID: 15564562
The structural basis of gas-responsive transcription by the human nuclear hormone receptor REV-ERBbeta.
PLoS biology Feb, 2009 | Pubmed ID: 19243223
Nuclear receptors homo sapiens Rev-erbbeta and Drosophila melanogaster E75 are thiolate-ligated heme proteins which undergo redox-mediated ligand switching and bind CO and NO.
Biochemistry Jul, 2009 | Pubmed ID: 19405475
The Drosophila DHR96 nuclear receptor binds cholesterol and regulates cholesterol homeostasis.
Genes & development Dec, 2009 | Pubmed ID: 19952106
Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components.
Cell May, 2016 | Pubmed ID: 27160350
Portable, On-Demand Biomolecular Manufacturing.
Cell Sep, 2016 | Pubmed ID: 27662092
BioBits™ Explorer: A modular synthetic biology education kit.
Science advances Aug, 2018 | Pubmed ID: 30083608
BioBits™ Bright: A fluorescent synthetic biology education kit.
Science advances Aug, 2018 | Pubmed ID: 30083609
Perspective: Solidifying the impact of cell-free synthetic biology through lyophilization.
Biochemical engineering journal Oct, 2018 | Pubmed ID: 30740032
Synthetic Biology Goes Cell-Free.
BMC biology 08, 2019 | Pubmed ID: 31395057
A multiplexed, electrochemical interface for gene-circuit-based sensors.
Nature chemistry 01, 2020 | Pubmed ID: 31767994
Loop-Mediated Isothermal Amplification (LAMP) for the Diagnosis of Zika Virus: A Review.
Viruses 12, 2019 | Pubmed ID: 31877989
When robotics met fluidics.
Lab on a chip 02, 2020 | Pubmed ID: 31895394
Clinical and Laboratory Diagnosis of SARS-CoV-2, the Virus Causing COVID-19.
ACS infectious diseases 09, 2020 | Pubmed ID: 32786280
Adaptive, diverse and de-centralized diagnostics are key to the future of outbreak response.
BMC biology 10, 2020 | Pubmed ID: 33115440
A glucose meter interface for point-of-care gene circuit-based diagnostics.
Nature communications 02, 2021 | Pubmed ID: 33526784
Development and validation of a one-step reverse transcription loop-mediated isothermal amplification (RT-LAMP) for rapid detection of ZIKV in patient samples from Brazil.
Scientific reports 02, 2021 | Pubmed ID: 33602985
High-Efficiency Protection of Linear DNA in Cell-Free Extracts from and .
ACS synthetic biology 07, 2021 | Pubmed ID: 34161082
Decentralizing Cell-Free RNA Sensing With the Use of Low-Cost Cell Extracts.
Frontiers in bioengineering and biotechnology , 2021 | Pubmed ID: 34497801
Logic invades cell-free biosensing.
Nature chemical biology 04, 2022 | Pubmed ID: 35177838
Toward Mail-in-Sensors for SARS-CoV-2 Detection: Interfacing Gel Switch Resonators with Cell-Free Toehold Switches.
ACS sensors 03, 2022 | Pubmed ID: 35254055
Field validation of the performance of paper-based tests for the detection of the Zika and chikungunya viruses in serum samples.
Nature biomedical engineering 03, 2022 | Pubmed ID: 35256758
Portable sample processing for molecular assays: application to Zika virus diagnostics.
Lab on a chip 05, 2022 | Pubmed ID: 35357372
Multicenter international assessment of a SARS-CoV-2 RT-LAMP test for point of care clinical application.
PloS one , 2022 | Pubmed ID: 35544541
Recent insights into SARS-CoV-2 omicron variant.
Reviews in medical virology Jun, 2022 | Pubmed ID: 35662313
Katariina Jaenes*,1,
Severino Jefferson Ribeiro da Silva*,1,2,
Justin R. J. Vigar*,1,
Kaiyue Wu3,4,
Masoud Norouzi1,
Pouriya Bayat1,
Margot Karlikow1,
Seray Cicek1,
Yuxiu Guo1,
Alexander A. Green3,4,
Lindomar Pena2,
Keith Pardee1,5
1Leslie Dan Faculty of Pharmacy, University of Toronto,
2Laboratory of Virology and Experimental Therapy (LAVITE), Department of Virology, Aggeu Magalhães Institute (IAM), Oswaldo Cruz Foundation (Fiocruz),
3Department of Biomedical Engineering, Boston University,
4Molecular Biology, Cell Biology & Biochemistry Program, Graduate School of Arts and Sciences, Boston University,
5Department of Mechanical and Industrial Engineering, University of Toronto
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