Shannon McKinney-Freeman

Childrens Hospital,
Harvard Stem Cell Institute,
Childrens Hospital, Harvard Stem Cell Institute

Harvard Medical School

BIOGRAPHY

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PUBLICATIONS

Muscle-derived hematopoietic stem cells are hematopoietic in origin.

Proceedings of the National Academy of Sciences of the United States of America Feb, 2002 | Pubmed ID: 11830662

Altered phenotype and reduced function of muscle-derived hematopoietic stem cells.

Experimental hematology Sep, 2003 | Pubmed ID: 12962727

Circulating hematopoietic stem cells do not efficiently home to bone marrow during homeostasis.

Experimental hematology Sep, 2004 | Pubmed ID: 15345289

Isolation and characterization of side population cells.

Methods in molecular biology (Clifton, N.J.) , 2005 | Pubmed ID: 15361673

Phenotype and origin of human skeletal muscle-derived hematopoietic progenitors.

Leukemia research Apr, 2005 | Pubmed ID: 15725468

Differential mRNA processing in hematopoietic stem cells.

Stem cells (Dayton, Ohio) Mar, 2006 | Pubmed ID: 16373690

The cdx-hox pathway in hematopoietic stem cell formation from embryonic stem cells.

Annals of the New York Academy of Sciences Jun, 2007 | Pubmed ID: 17303828

Towards hematopoietic reconstitution from embryonic stem cells: a sanguine future.

Current opinion in hematology Jul, 2007 | Pubmed ID: 17534159

Modulation of murine embryonic stem cell-derived CD41+c-kit+ hematopoietic progenitors by ectopic expression of Cdx genes.

Blood May, 2008 | Pubmed ID: 18252864

BMP and Wnt specify hematopoietic fate by activation of the Cdx-Hox pathway.

Cell stem cell Jan, 2008 | Pubmed ID: 18371423

Cdx gene deficiency compromises embryonic hematopoiesis in the mouse.

Proceedings of the National Academy of Sciences of the United States of America Jun, 2008 | Pubmed ID: 18511567

Isolation of hematopoietic stem cells from mouse embryonic stem cells.

Current protocols in stem cell biology Feb, 2008 | Pubmed ID: 18770632

Surface antigen phenotypes of hematopoietic stem cells from embryos and murine embryonic stem cells.

Blood Jul, 2009 | Pubmed ID: 19420357

Biomechanical forces promote embryonic haematopoiesis.

Nature Jun, 2009 | Pubmed ID: 19440194

Cdx4 is dispensable for murine adult hematopoietic stem cells but promotes MLL-AF9-mediated leukemogenesis.

Haematologica Oct, 2010 | Pubmed ID: 20494928

The transcriptional landscape of hematopoietic stem cell ontogeny.

Cell stem cell Nov, 2012 | Pubmed ID: 23122293

The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity.

Experimental cell research Jul, 2013 | Pubmed ID: 23528453

Nfix is a novel regulator of murine hematopoietic stem and progenitor cell survival.

Blood Oct, 2013 | Pubmed ID: 24041575

Effect of developmental stage of HSC and recipient on transplant outcomes.

Developmental cell Jun, 2014 | Pubmed ID: 24914562

INSTITUTIONS

Harvard Medical School

JOVE ARTICLES

Derivation of Hematopoietic Stem Cells from Murine Embryonic Stem Cells

Shannon McKinney-Freeman¹,

George Daley¹

¹Childrens Hospital, Harvard Stem Cell Institute, Harvard Medical School

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Shannon McKinney-Freeman

.css-o250i3{font-size:18px;font-family:Open Sans,sans-serif;line-height:21.6px;}Childrens Hospital,Harvard Stem Cell Institute,Childrens Hospital, Harvard Stem Cell Institute

Harvard Medical School

Derivation of Hematopoietic Stem Cells from Murine Embryonic Stem Cells

Childrens Hospital,
Harvard Stem Cell Institute,
Childrens Hospital, Harvard Stem Cell Institute