Niels Fertig

Microstructured apertures in planar glass substrates for ion channel research.

Microchip technology for automated and parallel patch-clamp recording.

Automated ion channel screening: patch clamping made easy.

Rapid screening of membrane protein activity: electrophysiological analysis of OmpF reconstituted in proteoliposomes.

Planar patch clamp: advances in electrophysiology.

Port-a-patch and patchliner: high fidelity electrophysiology for secondary screening and safety pharmacology.

The M34A mutant of Connexin26 reveals active conductance states in pore-suspending membranes.

Automated patch clamp on mESC-derived cardiomyocytes for cardiotoxicity prediction.

State-of-the-Art Automated Patch Clamp Devices: Heat Activation, Action Potentials, and High Throughput in Ion Channel Screening.

Green fluorescent protein changes the conductance of connexin 43 (Cx43) hemichannels reconstituted in planar lipid bilayers.

Characterizing human ion channels in induced pluripotent stem cell-derived neurons.

Minimized cell usage for stem cell-derived and primary cells on an automated patch clamp system.

Membrane assembly of the functional KcsA potassium channel in a vesicle-based eukaryotic cell-free translation system.

Temperature-sensitive gating of hCx26: high-resolution Raman spectroscopy sheds light on conformational changes.

Bilayer-spanning DNA nanopores with voltage-switching between open and closed state.

New easy-to-use hybrid system for extracellular potential and impedance recordings.

Antibiotic translocation through porins studied in planar lipid bilayers using parallel platforms.

Novel screening techniques for ion channel targeting drugs.

Automated Patch Clamp Meets High-Throughput Screening: 384 Cells Recorded in Parallel on a Planar Patch Clamp Module.

A biomimetic DNA-based channel for the ligand-controlled transport of charged molecular cargo across a biological membrane.

Safety pharmacology studies using EFP and impedance.

Identification of Drug-Drug Interactions In Vitro: A Case Study Evaluating the Effects of Sofosbuvir and Amiodarone on hiPSC-Derived Cardiomyocytes.

An update on the advancing high-throughput screening techniques for patch clamp-based ion channel screens: implications for drug discovery.

A novel gain-of-function mutation of Piezo1 is functionally affirmed in red blood cells by high-throughput patch clamp.

Real-time monitoring β-lactam/β-lactamase inhibitor (BL/BLI) mixture towards the bacteria porin pathway at single molecule level.

Automated Dynamic Clamp for Simulation of I in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Real Time Using Patchliner Dynamite.

Reliable identification of cardiac liability in drug discovery using automated patch clamp: Benchmarking best practices and calibration standards for improved proarrhythmic assessment.

Integration of mechanical conditioning into a high throughput contractility assay for cardiac safety assessment.

Electrophysiology on Channel-Forming Proteins in Artificial Lipid Bilayers: Next-Generation Instrumentation for Multiple Recordings in Parallel.

A Scalable Approach Reveals Functional Responses of iPSC Cardiomyocyte 3D Spheroids.

Reliable identification of cardiac conduction abnormalities in drug discovery using automated patch clamp II: Best practices for Nav1.5 peak current in a high throughput screening environment.

The suitability of high throughput automated patch clamp for physiological applications.

SSM-based electrophysiology, a label-free real-time method reveals sugar binding & transport events in SGLT1.

There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments.

A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes.