Hextan Yuen Sheung Ngan

Department of Obstetrics and Gynecology, The University of Hong Kong

Affiliated withThe University of Hong Kong

Research Area

Medicine

Biography

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JoVE Journal Publications

Article Total : 2	Year
Publication title	2022
Publication title	2024

Other Publications

Article	Year
p73 expression is associated with the cellular radiosensitivity in cervical cancer after radiotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15161684	2004
Expression of deltaNp73 and TAp73alpha independently associated with radiosensitivities and prognoses in cervical squamous cell carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16818688	2006
Potential use of the adenosine triphosphate cell viability assay in endometrial cancer. Journal of the Society for Gynecologic Investigation\| PubMed ID: 16979354	2006
Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carcinogenesis. International journal of cancer\| PubMed ID: 18404674	2008
Promoter methylation of death-associated protein kinase and its role in irradiation response in cervical cancer. Oncology reports\| PubMed ID: 18425396	2008
Functional polymorphisms in the BRCA1 promoter influence transcription and are associated with decreased risk for breast cancer in Chinese women. Journal of medical genetics\| PubMed ID: 18782836	2009
P63 expression in gestational trophoblastic disease: correlation with proliferation and apoptotic dynamics. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists\| PubMed ID: 19188816	2009
Interaction of TAp73 and breast cancer-associated gene 3 enhances the sensitivity of cervical cancer cells in response to irradiation-induced apoptosis. Cancer research\| PubMed ID: 20647320	2010
Overexpression of the Parkinson disease protein DJ-1 and its regulator PTEN in gestational trophoblastic disease. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists\| PubMed ID: 20736773	2010
Prevalence and risk factors of Human Papillomavirus (HPV) infection in southern Chinese women - a population-based study. PloS one\| PubMed ID: 21559276	2011
LY294002 and metformin cooperatively enhance the inhibition of growth and the induction of apoptosis of ovarian cancer cells. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society\| PubMed ID: 22080879	2012
TAp73-mediated the activation of c-Jun N-terminal kinase enhances cellular chemosensitivity to cisplatin in ovarian cancer cells. PloS one\| PubMed ID: 22900074	2012
Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade. BMC cancer\| PubMed ID: 23819460	2013
Reduced expression of AMPK-β1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer. Molecular cancer\| PubMed ID: 24602453	2014
Perfusion and diffusion characteristics of cervical cancer based on intraxovel incoherent motion MR imaging-a pilot study. European radiology\| PubMed ID: 24744198	2014
Targeting estrogen receptor subtypes (ERα and ERβ) with selective ER modulators in ovarian cancer. The Journal of endocrinology\| PubMed ID: 24819599	2014
Asian Society of Gynecologic Oncology International Workshop 2014. Journal of gynecologic oncology\| PubMed ID: 25609163	2015
Cyclophosphamide, hydroxyurea, actinomycin D, methotrexate, and vincristine in the treatment of gestational trophoblastic neoplasia. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society\| PubMed ID: 25628108	2015
The role of laparoscopy in staging of different gynaecological cancers. Best practice & research. Clinical obstetrics & gynaecology\| PubMed ID: 25819676	2015
The Significance of Mismatch Repair Deficiency in Young Patients With Endometrial Cancer. International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists\| PubMed ID: 26262451	2015
Chemotherapy in pregnancy. Best practice & research. Clinical obstetrics & gynaecology\| PubMed ID: 26553395	2016
Robot-assisted gynaecological cancer surgery-complications and prevention. Best practice & research. Clinical obstetrics & gynaecology\| PubMed ID: 28528932	2017
Apoptosis and Anti-cancer Drug Discovery: The Power of Medicinal Fungi and Plants. Current medicinal chemistry\| PubMed ID: 28730971	2018
Human papillomavirus E6 protein enriches the CD55(+) population in cervical cancer cells, promoting radioresistance and cancer aggressiveness. The Journal of pathology\| PubMed ID: 28944962	2018
ERBB2 mutation: A promising target in non-squamous cervical cancer. Gynecologic oncology\| PubMed ID: 29279289	2018
Methylation-associated silencing of promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways. Theranostics\| PubMed ID: 29290818	2018
Combined electroacupuncture and auricular acupuncture for postoperative pain after abdominal surgery for gynecological diseases: study protocol for a randomized controlled trial. Trials\| PubMed ID: 29301556	2018
GRO-α and IL-8 enhance ovarian cancer metastatic potential via the CXCR2-mediated TAK1/NFκB signaling cascade. Theranostics\| PubMed ID: 29507619	2018
Identification of nonsynonymous TP53 mutations in hydatidiform moles. Mutation research\| PubMed ID: 29655027	2018
A Case Series of Five Patients With Pure or Mixed Gestational Epithelioid Trophoblastic Tumors and a Literature Review on Mixed Tumors. American journal of clinical pathology\| PubMed ID: 29897391	2018
Hexokinase 2 Regulates Ovarian Cancer Cell Migration, Invasion and Stemness via FAK/ERK1/2/MMP9/NANOG/SOX9 Signaling Cascades. Cancers\| PubMed ID: 31212816	2019
CD71 Population Enriched by HPV-E6 Protein Promotes Cancer Aggressiveness and Radioresistance in Cervical Cancer Cells. Molecular cancer research : MCR\| PubMed ID: 31235657	2019
Ascites-derived ALDH+CD44+ tumour cell subsets endow stemness, metastasis and metabolic switch via PDK4-mediated STAT3/AKT/NF-κB/IL-8 signalling in ovarian cancer. British journal of cancer\| PubMed ID: 32390009	2020
Infiltration of T cells promotes the metastasis of ovarian cancer cells via the modulation of metastasis-related genes and PD-L1 expression. Cancer immunology, immunotherapy : CII\| PubMed ID: 32504248	2020
CD109 mediates tumorigenicity and cancer aggressiveness via regulation of EGFR and STAT3 signalling in cervical squamous cell carcinoma. British journal of cancer\| PubMed ID: 32507856	2020
MAP30 protein from Momordica charantia is therapeutic and has synergic activity with cisplatin against ovarian cancer in vivo by altering metabolism and inducing ferroptosis. Pharmacological research\| PubMed ID: 32814169	2020
Association between MRI histogram features and treatment response in locally advanced cervical cancer treated by chemoradiotherapy. European radiology\| PubMed ID: 32885298	2021
HPV-induced Nurr1 promotes cancer aggressiveness, self-renewal, and radioresistance via ERK and AKT signaling in cervical cancer. Cancer letters\| PubMed ID: 33010383	2021
Role of Nurr1 in Carcinogenesis and Tumor Immunology: A State of the Art Review. Cancers\| PubMed ID: 33086676	2020
Surgery including fertility-sparing treatment of GTD. Best practice & research. Clinical obstetrics & gynaecology\| PubMed ID: 33127305	2021
Development of a Multi-Institutional Prediction Model for Three-Year Survival Status in Patients with Uterine Leiomyosarcoma (AGOG11-022/QCGC1302 Study). Cancers\| PubMed ID: 34069227	2021
Genome-wide DNA methylome analysis identifies methylation signatures associated with survival and drug resistance of ovarian cancers. Clinical epigenetics\| PubMed ID: 34294135	2021
Correction to: Genome-wide DNA methylome analysis identifies methylation signatures associated with survival and drug resistance of ovarian cancers. Clinical epigenetics\| PubMed ID: 34344477	2021
COVID-19 related fear and depression of pregnant women and new mothers. Public health nursing (Boston, Mass.)\| PubMed ID: 34902184	2022
Adjuvant and post-surgical treatment in gynaecological cancers. Best practice & research. Clinical obstetrics & gynaecology\| PubMed ID: 35033279	2022
Germline mutations in Chinese ovarian cancer with or without breast cancer. Molecular genetics & genomic medicine\| PubMed ID: 35608067	2022
A combination of electroacupuncture and auricular acupuncture for postoperative pain after abdominal surgery for gynaecological diseases: A randomized controlled trial. Phytomedicine : international journal of phytotherapy and phytopharmacology\| PubMed ID: 35797863	2022